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  1. 2241
    “…We show here that soluble CD137 (sCD137), the alternately spliced gene product of Tnfsfr9, effectively treats acute type 1 diabetes (T1D) in nonobese diabetic (NOD) mice. sCD137 significantly delayed development of end-stage disease, preserved insulin+ islet beta cells, and prevented progression to end-stage T1D in some mice. …”
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    Soluble CD137 Ameliorates Acute Type 1 Diabetes by Inducing T Cell Anergy
  2. 2242
    por Kim, S-W, Li, W, Angel, R, Plumstead, P W
    Publicado 2019
    “…Work was done to modify a limestone solubility assay to improve predictions of in vivo apparent ileal digestibility of Ca (AID Ca) in broilers and impacts on AID P. …”
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    Modification of a limestone solubility method and potential to correlate with in vivo limestone calcium digestibility
  3. 2243
    “…Although the function of its predominant membrane-bound form is well established, the source and biological activity of soluble PD-L1 (sPD-L1) remain incompletely understood. …”
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    Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
  4. 2244
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    Water-soluble pristine C(60) fullerene attenuates acetaminophen-induced liver injury
  5. 2245
    “…The highest solubility of paprika extract was achieved at the temperature of 333.15 K and under the pressure of 50 MPa. …”
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    Experimental Data and Modelling of the Solubility of High-Carotenoid Paprika Extract in Supercritical Carbon Dioxide
  6. 2246
    “…We aimed to explore triggering receptor expressed on myeloid cells-1 (TREM-1) activation in familial Mediterranean fever (FMF), the most frequent monogenic auto-inflammatory disease, through the measurement of its serum soluble form, named sTREM-1. Blood samples from patients with FMF according to Livneh criteria followed in the French FMF national center and carrying two pathogenic MEFV mutations were collected. …”
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    In familial Mediterranean fever, soluble TREM-1 plasma level is higher in case of amyloidosis
  7. 2247
    “…The bioactive and anti-inflammatory role of human milk components has been recognized; active milk components include soluble forms of Toll-like receptors (TLRs). Preterm babies are more susceptible to infections and may succumb to necrotizing enterocolitis (NEC), a gastrointestinal disease which is exacerbated by an excessive inflammatory response after TLR activation. …”
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    Analysis of Toll-Like Receptors in Human Milk: Detection of Membrane-Bound and Soluble Forms
  8. 2248
    “…Water-miscible organic solvents, termed co-solvents, can be used to enhance the solubility of poorly soluble substances. Typically, drugs with poor aqueous solubility and Log P > 3 are not amenable to delivery across the skin. …”
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    Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules
  9. 2249
    “…By coupling a cellulase to this soluble outer membrane cytochrome, the export efficiency was measured by means of relative cellulase activity. …”
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    Soluble versions of outer membrane cytochromes function as exporters for heterologously produced cargo proteins
  10. 2250
    “…The results demonstrated that the water solubility of TSPCs was significantly greater than that of TPI (p <0.05). …”
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    Correlation Between the Water Solubility and Secondary Structure of Tilapia-Soybean Protein Co-Precipitates
  11. 2251
    “…Among them, the function of slt, which encodes soluble lytic transglycosylase (SLT) was investigated in detail. …”
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    Soluble lytic transglycosylase SLT of Francisella novicida is involved in intracellular growth and immune suppression
  12. 2252
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    A Soluble Humic Substance for the Simultaneous Removal of Cadmium and Arsenic from Contaminated Soils
  13. 2253
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    Soluble Sugar and Lipid Readjustments in the Yarrowia lipolytica Yeast at Various Temperatures and pH
  14. 2254
    “…The experimental solubility of PPD in mole fraction in neat DMSO was much higher than its ideal solubility, indicating the potential of DMSO for solubility enhancement of PPD. …”
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    Experimental and Computational Approaches for Solubility Measurement of Pyridazinone Derivative in Binary (DMSO + Water) Systems
  15. 2255
    “…We attribute this to enhanced product solubility in the aqueous or solvent fraction of the bioreactor liquid phase (depending on the derivative and medium used), with consequent enhanced product removal. …”
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    Bioderivatization as a concept for renewable production of chemicals that are toxic or poorly soluble in the liquid phase
  16. 2256
    “…The administration of recombinant human soluble thrombomodulin (rhsTM) significantly improves liver inflammation and increases the survival rate of patients with acute liver failure (ALF). …”
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    Enhanced effect of recombinant human soluble thrombomodulin by ultrasound irradiation in acute liver failure
  17. 2257
    “…Formation of SGs occurs at the trans-Golgi network (TGN) where their soluble cargo aggregates to form a dense core, but the mechanisms controlling the sorting of regulated secretory cargoes (soluble and transmembrane) away from constitutively secreted proteins remain unclear. …”
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    Differential sorting behavior for soluble and transmembrane cargoes at the trans-Golgi network in endocrine cells
  18. 2258
    “…The nuclear farnesoid X receptor (FXR) and the enzyme soluble epoxide hydrolase (sEH) are validated molecular targets to treat metabolic disorders such as non‐alcoholic steatohepatitis (NASH). …”
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    Dual Farnesoid X Receptor/Soluble Epoxide Hydrolase Modulators Derived from Zafirlukast
  19. 2259
    “…The sensors exhibit high sensitivity to water-soluble gases (e.g., lower limit of detection for NH(3) < 200 parts-per-billion) with a fast and reversible response. …”
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    Cellulose Fibers Enable Near-Zero-Cost Electrical Sensing of Water-Soluble Gases
  20. 2260
    “…Their highly soluble nature in various solvents enabled us to study the solvent effects of these molecules. …”
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    Facile synthesis of fluorescent hetero[8]circulene analogues with tunable solubilities and optical properties
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