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  1. 56661
    “…COS-1 cells were transfected with the above plasmids and co-cultured with untransfected MSCs, the intercellular transportations of the constructed proteins were studied by immunofluorescence. The solubility of VP22-hBcl-xL and hBcl-xL-VP22 was analyzed by Western blot. …”
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    The Study of the Intercellular Trafficking of the Fusion Proteins of Herpes Simplex Virus Protein VP22
  2. 56662
    “…Maize samples were analysed for starch, protein, crude fibre, fat, protein solubility index (PSI) and vitreousness using near infra red reflectance spectroscopy (NIR). …”
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    Effect of Xylanase on Performance and Apparent Metabolisable Energy in Starter Broilers Fed Diets Containing One Maize Variety Harvested in Different Regions of China
  3. 56663
    “…METHODS: A total of 55 feed ingredients, including 14 corn, 13 wheat bran, 11 soybean meal and 17 dried distillers grains with solubles (DDGS) as well as 76 complete swine feeds including 7 creep feeds, 14 starter feeds, 14 grower feeds, 18 grower-finisher feeds, 10 gestating sow feeds, and 13 lactating sow feeds were randomly collected from 15 swine farms located in the Beijing region of China from July to August 2011. …”
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    Occurrence of mycotoxins in feed ingredients and complete feeds obtained from the Beijing region of China
  4. 56664
    por Ahn, J. Y., Kil, D. Y., Kong, C., Kim, B. G.
    Publicado 2014
    “…In Exp. 1, the weight loss on drying (LOD) of corn, soybean meal (SBM), distillers dried grains with solubles (DDGS), whey permeate, whey powder, spray-dried porcine plasma (SDPP), fish meal, and a mixed diet of these 7 ingredients were measured by oven drying at 135°C for 2 h. …”
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    Comparison of Oven-drying Methods for Determination of Moisture Content in Feed Ingredients
  5. 56665
    “…In this study, we successfully synthesized two macromolecular prodrugs of SN38 with different conjugate positions (chitosan-(C(10)-OH)SN38 and chitosan-(C(20)-OH)SN38) to improve the water solubility and antitumor activity of SN38. These prodrugs can self-assemble into micelles in aqueous medium. …”
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    Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity
  6. 56666
    “…However, salinomycin displayed poor aqueous solubility that hinders its clinical application. The objective of this study was to develop salinomycin-loaded nanoparticles to eliminate CD133(+) osteosarcoma CSCs. …”
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    Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133(+) osteosarcoma cancer stem cells
  7. 56667
    “…Physicochemical properties such as solubility, fermentability, viscosity, and gel-forming ability differ among fiber types and are known to affect metabolism. …”
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    Resistant starch diet induces change in the swine microbiome and a predominance of beneficial bacterial populations
  8. 56668
    “…However, the poor aqueous solubility of ABZ limits its potential for cancer therapy. …”
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    Albumin nanoparticles increase the anticancer efficacy of albendazole in ovarian cancer xenograft model
  9. 56669
    “…Flow, thickness, and radiopacity tests were conducted in accordance with ISO 6876. Sorption and solubility (SL) tests were conducted in accordance with ISO 4049, pH was measured with a pH meter, and degree of conversion (DC) was evaluated with Fourier transform infrared spectroscopy (FTIR). …”
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    Physical-mechanical properties of Bis-EMA based root canal sealer with different fillers addition
  10. 56670
    “…We recommend to fill sterile-filtered water into serum bottles and to add (15−15)N(2) gas to the water in amounts exceeding the standard N(2) solubility, followed by vigorous agitation (vortex mixing ≥ 5 min). …”
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    Simple approach for the preparation of (15−15)N(2)-enriched water for nitrogen fixation assessments: evaluation, application and recommendations
  11. 56671
    “…However there were some clinical development drawbacks such as poor in vivo solubility, depreciation of biological activity upon exposure to an aqueous environment and non-specific targeting of tumour cells. …”
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    Recombinant human alpha fetoprotein synergistically potentiates the anti-cancer effects of 1′-S-1′-acetoxychavicol acetate when used as a complex against human tumours harbouring AFP-receptors
  12. 56672
    “…HLCs are similar to nHz and sHz in terms of solubility, macroscopic and microscopic appearance although PXRD, FTIR and RS confirm that the haem aggregates of HLCs are structurally different. …”
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    Characterization and optimization of the haemozoin-like crystal (HLC) assay to determine Hz inhibiting effects of anti-malarial compounds
  13. 56673
    “…RBG has strong antitumor effects, but its poor aqueous solubility and its cardiotoxicity have limited its clinical use. …”
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    Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy
  14. 56674
    “…The free mCRP subunit undergoes a non-proteolytic conformational change that has unique solubility, antigenicity, and bioactivity compared to the subunits that remain associated in the native, pentameric CRP molecule (i.e., pCRP). …”
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    Solubilization and purification of recombinant modified C-reactive protein from inclusion bodies using reversible anhydride modification
  15. 56675
    por Baker, Siân, Götz, Jürgen
    Publicado 2016
    “…The data demonstrates that a local OA insult can rapidly initiate changes in protein phosphorylation, solubility and aggregation at anatomically distant sites. …”
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    A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions
  16. 56676
    “…BACKGROUND: Curcumin (Ccm) has shown immense potential as an antimalarial agent; however its low solubility and less bioavailability attenuate the in vivo efficacy of this potent compound. …”
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    Short peptide based nanotubes capable of effective curcumin delivery for treating drug resistant malaria
  17. 56677
    “…Its clinical development has been hampered by its poor solubility. To address this problem, methoxy poly(ethylene glycol)-2000 (mPEG(2K))–SN38 and mPEG(2K)–poly(lactide) (PLA(1.5K))–SN38 conjugates were prepared and then dispersed into an aqueous medium to form micelles. …”
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    Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
  18. 56678
    “…PURPOSE: The Hedgehog pathway inhibitor vismodegib exhibits pH-dependent solubility, and in vitro studies have shown that vismodegib is a substrate of P-glycoprotein (P-gp) and is metabolized by cytochrome P450 (CYP) 2C9 and 3A4. …”
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    A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib
  19. 56679
    “…BACKGROUND: Levan and levan-type fructo-oligosaccharides (LFOs) have various potential applications in pharmaceutical and food industries due to their beneficial properties such as their low intrinsic viscosity and high water solubility. Previous studies showed that they exhibited prebiotic effects, anti-inflammatory and anti-tumor activities against Sarcoma-180 tumor cells of human. …”
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    Replica exchange molecular dynamics simulations reveal the structural and molecular properties of levan-type fructo-oligosaccharides of various chain lengths
  20. 56680
    “…CONCLUSIONS: Results with flowthrough pretreatment show that about 65–70% of the lignin is solubilized and removed before it can react further to form low solubility lignin rich fragments that deposit on the biomass surface in batch operations and hinder enzyme action. …”
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    Flowthrough pretreatment with very dilute acid provides insights into high lignin contribution to biomass recalcitrance
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