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  1. 661
    “…Proliposomes were used to improve the solubility and oral bioavailability of nifedipine. Nifedipine proliposomes were prepared by methanol injection-spray drying method. …”
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    A Liposomal Formulation for Improving Solubility and Oral Bioavailability of Nifedipine
  2. 662
    “…Hence, we first investigated the solubility of (S)-ZPF, screened solubilizers and performed the pharmacokinetic study of (S)-ZPF in the presence of the solubilizers. …”
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    A thorough analysis of the effect of surfactant/s on the solubility and pharmacokinetics of (S)-zaltoprofen
  3. 663
    “…Solubility is an important, albeit not well understood, feature determining protein behavior. …”
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    SODA: prediction of protein solubility from disorder and aggregation propensity
  4. 664
    “…We have synthesized water-soluble complexes between the antiviral drug arbidol and polymer compounds with molecular masses of 19–31 kDa representing copolymers of acrylamide (AA) and 2-acrylamido-2-methylpropanesulfonic acid (AAMPS). …”
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    Synthesis and biological activity of water-soluble polymer complexes of arbidol
  5. 665
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    Differences in the chitinolytic activity of mammalian chitinases on soluble and insoluble substrates
  6. 666
    “…Introduction of solubilizing long alkyl chains into an indigo molecule via formation of arylimino moieties at its carbonyl sites and amidation at its amino groups greatly enhances the solubility in diesel and several common organic solvents. …”
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    Highly Soluble Indigo Derivatives as Practical Diesel Absorption Markers
  7. 667
    “…Secreted E2 was found to contain both O-linked and N-linked complex glycans, whereas secreted E1 retained virus neutralization and hemagglutination epitopes, suggesting the possibility of using soluble RV antigens as subunit vaccines and for serodiagnostic purposes. …”
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    Expression of soluble forms of rubella virus glycoproteins in mammalian cells
  8. 668
    “…BACKGROUND: Soluble Klotho has multiple systemic salutary effects. …”
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    Performance of soluble Klotho assays in clinical samples of kidney disease
  9. 669
    por Seneci, Pierfausto
    Publicado 2015
    “…They are designed to restore its impaired capacity to dispose of soluble, dysfunctional protein copies, and to fight its pathological impairment in proteinopathies in general and in tauopathies in particular. …”
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    Targeting Proteasomal Degradation of Soluble, Misfolded Proteins: Ubi Major…
  10. 670
    “…OBJECTIVE: To systematically analyze soluble interleukin-2 receptor (sIL-2R) in CSF as a diagnostic and disease activity biomarker in patients with sarcoidosis involving the CNS (neurosarcoidosis). …”
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    Analysis of soluble interleukin-2 receptor as CSF biomarker for neurosarcoidosis
  11. 671
    “…The ectodomain of TREM2 is processed by a disintegrin and metalloprotease, resulting in the release of a soluble form of TREM2 (sTREM2). Recent studies have demonstrated that sTREM2 is a bioactive molecule capable of binding ligands, activating microglia, and regulating immune responses during the AD continuum. …”
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    TREM2 ectodomain and its soluble form in Alzheimer’s disease
  12. 672
    “…BACKGROUND: In this study, we aimed to design a novel oral insulin delivery system, named “oil-soluble” reversed lipid nanoparticles (ORLN), in which a hydrophilic insulin molecule is encapsulated by a phospholipid (PC) shell and dissolved in oil to prevent the enzymatic degradation of insulin. …”
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    “Oil-soluble” reversed lipid nanoparticles for oral insulin delivery
  13. 673
    “…This paper present the synthesis of bismuth (III) oxofumarate (BiO)(2)C(4)H(2)O(4) by solution-solid reaction due to the interaction of basic bismuth nitrates [Bi(6)O(5)(OH)(3)](NO(3))(5)·3H(2)O and [Bi(6)O(4)(OH)(4)](NO(3))(6)·H(2)O with aqueous solutions of fumaric acid C(4)H(4)O(4). Solubility of (BiO)(2)C(4)H(2)O(4) in various organic solvents has been investigated. …”
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    Synthesis of bismuth (III) oxofumarate and its solubility in organic solvents
  14. 674
    “…We recently showed that soluble CALR inhibited the phagocytosis of cancer cells by dendritic cells, thus dampening anticancer immune responses. …”
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    Surface-exposed and soluble calreticulin: conflicting biomarkers for cancer prognosis
  15. 675
    por Tran, Thao T. D., Tran, Phuong H. L.
    Publicado 2020
    “…Typically, the detection of molecular interactions will assist in the explanation of different drug performances (e.g., dissolution, solubility, stability) in solid dispersions. Various prominent reviews on solid dispersions have been reported recently. …”
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    Molecular Interactions in Solid Dispersions of Poorly Water-Soluble Drugs
  16. 676
    “…However, it is poorly soluble in water, and its bioavailability is limited. …”
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    Cyclodextrin Complexation Improves the Solubility and Caco-2 Permeability of Chrysin
  17. 677
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    Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF
  18. 678
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    Human recombinant soluble ACE2 in severe COVID-19
  19. 679
    “…In this paper, we review how soluble mediators of the inflammatory niche (cytokines and alarmins) influence the regenerative and immunomodulatory capacity of MSCs, highlighting the major advantages and concerns regarding the therapeutic potential of these inflammatory primed MSCs. …”
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    Inflammatory niche: Mesenchymal stromal cell priming by soluble mediators
  20. 680
    “…As the solubility of nisin is controlled by the residues of the hinge region, we have performed molecular dynamics simulations of various mutants and studied their effects on nisin’s solubility. …”
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    Altering the Solubility of the Antibiotic Candidate Nisin—A Computational Study
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