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  1. 1861
    “…Variants in genes encoding the soluble guanylyl cyclase (sGC) in platelets are associated with coronary artery disease (CAD) risk. …”
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    Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation
  2. 1862
    “…A novel pathway to bolster NO activity is to upregulate soluble guanylate cyclase (sGC), an enzyme responsible for mediating the protective actions of NO. …”
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    Ameliorating diabetes-associated atherosclerosis and diabetic nephropathy through modulation of soluble guanylate cyclase
  3. 1863
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    Decreased Levels of Soluble Developmental Endothelial Locus-1 Are Associated with Thrombotic Microangiopathy in Pregnancy
  4. 1864
    “…Although display methods such as phage display offer high-throughput, affinities of individual antibodies need to be accurately measured in soluble format. We have developed a screening platform capable of providing genotyped functional data from a total of 9216 soluble, individual antigen binding fragment (Fab) clones by employing next-generation sequencing (NGS) with hierarchical indexing. …”
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    Genotyped functional screening of soluble Fab clones enables in-depth analysis of mutation effects
  5. 1865
    “…We here aim to decipher whether plasma concentration of the soluble form of TREM-1 (sTREM-1) could predict the outcome of hospitalized COVID-19 patients. …”
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    Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients
  6. 1866
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    SOBA (soluble oligomer binding assay): A breakthrough or the early diagnosis of Alzheimer's disease
  7. 1867
    “…Here, we present a systematic study that quantifies solvent–supramolecular polymer compatibility using the Hansen solubility parameters (δ(D), δ(H), and δ(P)). We first studied the solubility space of the supramolecular building block triazine-1,3,5-tribenzenecarboxamide S-T. …”
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    Solvent-Induced Pathway Complexity of Supramolecular Polymerization Unveiled Using the Hansen Solubility Parameters
  8. 1868
    “…We used a pathogenic soluble tau peptide (T-peptide) model of tau aggregation and mice with genetically encoded endothelial Ca(2+) sensors to measure cerebrovascular endothelial responses to tau exposure. …”
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    Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature
  9. 1869
    por Gomez-Blanco, Nina, Prato, Maurizio
    Publicado 2023
    “…Using metal coordination to assemble carbon nanodots (CND) into clusters can enhance their photophysical properties for applications in sensing and biomedicine. Water-soluble clusters of CNDs are prepared by one-step microwave synthesis starting from ethylenediaminetetraacetic acid, ethylenediamine and MnCl(2)·4H(2)O as precursors. …”
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    Microwave-assisted one-step synthesis of water-soluble manganese-carbon nanodot clusters
  10. 1870
    “…Importantly, blockade of the PD-1/PD-L1 axis has been shown to reverse NK cell exhaustion and increase their cytotoxicity. Recently, soluble counterparts of checkpoint receptors, such as soluble PD-1 (sPD-1), are rising high interest due to their biological activity and ability to modulate immune responses. …”
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    Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells
  11. 1871
    “…The aim of this study was to investigate the relationship between LCN2, soluble transferrin receptor (sTfR), erythropoietin (EPO), reticulocyte production, and the prevalence of anemia in MRD. …”
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    Lipocalin-2, Soluble Transferrin Receptor, and Erythropoietin in Anemia During Mild Renal Dysfunction
  12. 1872
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    Nanostructured Lipid Carriers to Enhance the Bioavailability and Solubility of Ranolazine: Statistical Optimization and Pharmacological Evaluations
  13. 1873
    “…Elevated levels of soluble NKG2D ligands occurred potentially due to complex mechanisms of oxidative stress, with insufficient metabolism and excretion in a uremic milieu, but they might mask the significance of elevations in serum levels of soluble NKG2DLs in patients with a cancer history.…”
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    Levels of Soluble NKG2D Ligands and Cancer History in Patients Starting Hemodialysis
  14. 1874
    “…Chitosan (CS) is only soluble in weak acid medium, thereby limiting its wide utilisation in the field of biomedicine, food, and agriculture. …”
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    Preparation of water-soluble chitosan oligosaccharides by oxidative hydrolysis of chitosan powder with hydrogen peroxide
  15. 1875
    “…Therefore, we conducted a population-based cohort study to investigate the relationship between soluble α-klotho and all-cause mortality in a nationally representative sample of middle-aged and older adults in the United States (U.S.). …”
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    Association between soluble α-klotho and mortality risk in middle-aged and older adults
  16. 1876
    “…Human soluble epoxide hydrolase (sEH), a dual-functioning homodimeric enzyme with hydrolase and phosphatase activities, is known for its pivotal role in the hydrolysis of epoxyeicosatrienoic acids. …”
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    In Silico Modeling and Structural Analysis of Soluble Epoxide Hydrolase Inhibitors for Enhanced Therapeutic Design
  17. 1877
    “…However, the aqueous solubility of this drug is limited, as is its permeability. …”
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    Intermolecular Interactions as a Measure of Dapsone Solubility in Neat Solvents and Binary Solvent Mixtures
  18. 1878
    “…BCS class II drugs exhibit low aqueous solubility and high permeability. Such drugs often have an incomplete or erratic absorption profile. …”
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    Effect of hydrophilic polymers on the solubility and dissolution enhancement of rivaroxaban/beta-cyclodextrin inclusion complexes
  19. 1879
    “…The physical properties of the water-soluble glycopolymer bearing porphyrin moieties were examined in aqueous media, and the results also indicated the incorporation of TPP moieties in the polymer. …”
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    Preparation of a Water-Soluble Glycopolymer Bearing Porphyrin Skeletons and Its Biological Properties
  20. 1880
    “…In this paper, an oil-soluble catalyst was synthesized to catalyze the pyrolysis reaction of heavy oil in collaboration with reservoir minerals, so as to achieve efficient viscosity reduction of heavy oil and reduce production costs. …”
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    Oil-Soluble Exogenous Catalysts and Reservoir Minerals Synergistically Catalyze the Aquathermolysis of Heavy Oil
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