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  1. 2141
    “…Expression analysis of stress-responsive genes in GbRLK Arabidopsis revealed that there was increased expression of genes involved in the ABA-dependent signaling pathway (AtRD20, AtRD22 and AtRD26) and antioxidant genes (AtCAT1, AtCCS, AtCSD2 and AtCSD1) but not ion transporter genes (AtNHX1, AtSOS1). CONCLUSIONS: GbRLK is involved in the drought and high salinity stresses pathway by activating or participating in the ABA signaling pathway. …”
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    A receptor-like kinase gene (GbRLK) from Gossypium barbadense enhances salinity and drought-stress tolerance in Arabidopsis
  2. 2142
    “…Very recently, we have reported about an unconventional mode of elicitation of Mitomycin C (MMC) specific resistance in lexA3 (SOS repair deficient) mutants due to a combination of Rif-Nal mutations (rpoB87-gyrA87). …”
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    Selective Alleviation of Mitomycin C Sensitivity in lexA3 Strains of Escherichia coli Demands Allele Specificity of rif-nal Mutations: A Pivotal Role for rpoB87-gyrA87 Mutations
  3. 2143
    “…Targeted NGS has been successfully applied over 92% of the regions of interest, including exons for the following genes: PTPN11, SOS1, RAF1, BRAF, HRAS, KRAS, NRAS, SHOC, MAP2K1, MAP2K2, CBL. …”
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    Diagnosis of Noonan syndrome and related disorders using target next generation sequencing
  4. 2144
    “…Importantly, the treatment of U0126 significantly inhibited MEK/ERK signaling pathway molecules and severely impaired virus replication., Additionally, EV71 infection promoted the expression of son of sevenless (SOS1) and increased the secretion of IL-1α, IL-2, IL-6, IL-12, TNF-α,IFN-β and IFN-γ. …”
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    MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells
  5. 2145
    “…KHG is poorly characterized in plants but is broken down to pyruvate and glyoxylate after the E. coli SOS response to facilitate the resumption of respiration. …”
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    Tobacco drought stress responses reveal new targets for Solanaceae crop improvement
  6. 2146
    “…METHODS: We tested for an association between subsequent shock delivery in EMS resuscitation and clinical outcomes in patients with initially non-shockable rhythms (n = 11,481) through a survey of patients after out-of-hospital cardiac arrest in the Kanto region (SOS-KANTO) 2012 study cohort, Japan. The primary investigated outcome was 1-month survival with favorable neurological functions. …”
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    Subsequent shock deliveries are associated with increased favorable neurological outcomes in cardiac arrest patients who had initially non-shockable rhythms
  7. 2147
    “…METHODS: We studied adult OHCA patients in the Survey of Survivors after Out-of-Hospital Cardiac Arrest in the Kanto Region (SOS-KANTO) 2012 study from January 2012 to March 2013 in Japan. …”
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    Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study
  8. 2148
    “…In Escherichia coli, repair of DNA double-strand breaks is switched to a mutagenic mode, using error-prone DNA polymerases, via the SOS DNA damage and general (σ(S)) stress responses. …”
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    The Small RNA GcvB Promotes Mutagenic Break Repair by Opposing the Membrane Stress Response
  9. 2149
    “…The transcription levels of several general stress marker genes (BnRD29A, BnERD15, and BnLEA1) were higher in the transgenic plants than the wild-type plants, whereas salt-responsive genes (BnSOS1, BnNHX1, and BnHKT) were not significantly different or even reduced compared with the wild-type plants, which indicated that BnSIP1-1 specifically exerted different regulatory mechanisms on the osmotic- and salt-response pathways in seedling period. …”
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    BnSIP1-1, a Trihelix Family Gene, Mediates Abiotic Stress Tolerance and ABA Signaling in Brassica napus
  10. 2150
    “…(v) lac-amplified cells are not SOS-induced, as was proposed to explain elevated mutation in a sequential model. …”
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    Adaptive Amplification and Point Mutation Are Independent Mechanisms: Evidence for Various Stress-Inducible Mutation Mechanisms
  11. 2151
    “…After exclusion of 4 patients with suspected type 1 diabetes, and 11 patients with unknown glucose status at baseline, 4032 of the 4047 participants in the SOS study were included in the current analysis. …”
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    Long-term Incidence of Microvascular Disease after Bariatric Surgery or Usual Care in Patients with Obesity Stratified by Baseline Glucose Status
  12. 2152
    “…There were significant negative correlations between FSH and Speed of Sound (SOS) (r=−0.16; p<0.01), and between osteoporosis with age (r=−0.30, p<0.05) and number of childbirths (r=−0.14 p<0.05). …”
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    Correlation between Reproductive Hormonal Level and Osteoporosis among Women in Mongolia
  13. 2153
    “…Probes in genes SNED1(IRE-BP1), KLHL6, WDR51A(POC1A), CYTH4-ELFN2, CFLAR, PRDM14, SOS1, ZNF643(ZFP69B), ST6GAL1, C3orf70, CILP2, MLLT4 and ncRNA LOC101929268 remained significantly associated after Bonferroni-correction of P-values. …”
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    DNA-Methylation and Body Composition in Preschool Children: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study
  14. 2154
    “…Forced expression of miR-23b cluster or miR-125a-5p enhanced drug sensitivity and suppressed invasiveness of NSCLC cells by silencing several genes involved in oncogenic KRAS and NF-kB pathways, including SOS1, GRB2, IQGAP1, RALA, RAF-1, IKKβ, AKT2, ERK2 and KRAS itself. …”
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    PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways
  15. 2155
    “…Intriguingly, miR-193a-3p not only modulated GRB7 but also ERBB4, SOS2 and KRAS in the MAPK/ERK signaling pathway to enhance the oncogenic properties of ovarian cancer cells in vitro and in vivo. …”
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    Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways
  16. 2156
    “…Fifty-three voluntary telecommunicators working at SOS Alarm were recruited nationally. Each telecommunicator handled 26 emergency medical calls, simulated by experienced standard patients. …”
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    A comparison of two emergency medical dispatch protocols with respect to accuracy
  17. 2157
    “…At the transcriptome level, the over-expression of OsHAK1 stimulated a number of stress-responsive genes as well as four genes known to be involved in Na(+) homeostasis and the salinity response (OsHKT1;5, OsSOS1, OsLti6a and OsLti6b). When the stress was applied at booting through to maturity, the OsHAK1 over-expressors out-yielded wild type by 25%, and no negative pleiotropic effects were expressed in plants gown under non-saline conditions. …”
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    Variation in the Abundance of OsHAK1 Transcript Underlies the Differential Salinity Tolerance of an indica and a japonica Rice Cultivar
  18. 2158
    “…Gene expression profiling of sodium transporters, Sodium proton exchanger (NHX3), Vacuolar ATPase (vATPase) and Salt overly sensitive1 (SOS1) showed up regulation under salt stress after 6–24 hr of NaCl treatment. …”
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    Temporal and spatial changes in ion homeostasis, antioxidant defense and accumulation of flavonoids and glycolipid in a halophyte Sesuvium portulacastrum (L.) L.
  19. 2159
    “…Meanwhile, Streptomyces strain 3BQP-1 produces bioactive compound inducing SOS-response due to DNA damage. In conclusion, this study proved mangrove plants harbored a high diversity of cultivable endophytic actinobacteria, which can be a promising source for discovery of novel species and bioactive compounds.…”
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    Diversity, Novelty, and Antimicrobial Activity of Endophytic Actinobacteria From Mangrove Plants in Beilun Estuary National Nature Reserve of Guangxi, China
  20. 2160
    “…The decreased leaf Na(+) content of pumpkin-grafted plants was achieved by higher Na(+) exclusion in roots, which was driven by the Na(+)/H(+) antiporter energized by the plasma membrane H(+)-ATPase, as evidenced by the higher plasma membrane H(+)-ATPase activity and higher transcript levels for PMA and SOS1. In addition, early stomatal closure was also observed in the pumpkin-grafted cucumber plants, reducing water loss and maintaining the plant’s hydration status. …”
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    Root respiratory burst oxidase homologue-dependent H(2)O(2) production confers salt tolerance on a grafted cucumber by controlling Na(+) exclusion and stomatal closure
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