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  1. 2261
    “…Ten of these variants were in PTPN11, SOS1, KRAS, BRAF, and NF1, all predicted to constitutively activate Ras/Raf/mitogen-activated protein kinase (MAPK) signaling. …”
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    Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy
  2. 2262
    “…METHODS: In 2008, the Public Private Partnership, Stamp Out Sleeping Sickness (SOS) administered a single dose of trypanocide to 31 486 head of cattle in 29 parishes in Dokolo and Kaberamaido districts. …”
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    Evaluating the impact of targeting livestock for the prevention of human and animal trypanosomiasis, at village level, in districts newly affected with T. b. rhodesiense in Uganda
  3. 2263
    “…We found that CDPKs (calmodulin-like domain protein kinases), SOS3 (salt overly sensitive3), MAPKs (mitogen-activated protein kinase cascades), RLKs (receptor like kinase), and LRR-RLKs (repeat leucine-rich receptor kinase) were firstly involved in response to drought stress in drought tolerant A. wellbyi. …”
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    Key factors for differential drought tolerance in two contrasting wild materials of Artemisia wellbyi identified using comparative transcriptomics
  4. 2264
    “…Additionally, a set of more than 15 candidate transcripts are proposed to be potential components of the salt overly sensitive (SOS) pathway in chickpea. Newly identified transcript isoforms are potential targets for breeding novel cultivars with high salinity tolerance. …”
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    The salt-responsive transcriptome of chickpea roots and nodules via deepSuperSAGE
  5. 2265
    “…Whereas no significant increase of mesophyll cell vacuolar Na(+) intensity was observed in PNC treated plants than the NNP control under salinity stress, suggesting that the enhanced leaf K(+) retention and leaf Na(+) exclusion, but not leaf vacuolar Na(+) sequestration are the main mechanisms behind PNC improved cotton salt tolerance. qPCR results showed that under salinity stress, the modulation of HKT1 but not SOS1 refers more to the PNC improved cotton leaf Na(+) exclusion than the NNP control. …”
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    Cerium oxide nanoparticles improve cotton salt tolerance by enabling better ability to maintain cytosolic K(+)/Na(+) ratio
  6. 2266
    “…SUMMARY ANSWER: Eleven genes (AKT1, ARHGEF7, BCL2L1, CCND1, E2F1, HRAS, KCNH2, PIK3C2A, SHC1, SOS1 and SPP1) in the PI3K/AKT pathway were significantly down-regulated in CCs from oocytes that went on to produce a pregnancy compared to CCs associated with a negative outcome. …”
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    Cumulus cells surrounding oocytes with high developmental competence exhibit down-regulation of phosphoinositol 1,3 kinase/protein kinase B (PI3K/AKT) signalling genes involved in proliferation and survival
  7. 2267
    “…BACKGROUND: Pediatric athletes commonly sustain inversion-type ankle fractures.(1,2) Approximately 1% will form post-traumatic subfibular ossicles (SO), especially after tip avulsion fractures.(3,4) Athletes with SOs can have pain and recurrent sprains.(5,6,7) Here we show the utility of magnetic resonance imaging (MRI) in clinical decision-making for athletes with ankle symptoms and the presence of a SO. …”
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    THE UTILITY OF MRI IN CLINICAL DECISION-MAKING FOR PEDIATRIC ATHLETES WITH SYMPTOMATIC SUBFIBULAR OSSICLES
  8. 2268
    “…METHODS: Patients who underwent arthroscopic anterior labral repairs were selected from the Surgical Outcomes System (SOS) registry between January 2011 and July 2020. …”
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    Poster 171: Does the addition of remplissage to arthroscopic labral repair result in decreased patients’ perception of their shoulder function and clinical outcome?
  9. 2269
    “…METHODS: Data came from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network during the 2011/12, 2012/13, and 2013/14 influenza seasons; all patients were aged 65+. …”
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    Frailty Hinders Recovery From Acute Respiratory Illness in Older Adults
  10. 2270
    Libro
    Folletos de la Colección Juan de la Cabada : volúmenes 351-400.
  11. 2271
    “…The pathways associated with any endometriosis were Grb2-Sos provides linkage to MAPK signaling for integrins pathway (P = 2.8 × 10(−5), FDR-P = 3.0 × 10(−3)), Wnt signaling (P = 0.026, FDR-P = 0.026) and p130Cas linkage to MAPK signaling for integrins pathway (P = 6.0 × 10(−4), FDR-P = 0.029); with Stage A endometriosis: extracellular signal-regulated kinase (ERK)1 ERK2 MAPK (P = 5.0 × 10(−4), FDR-P = 5.0 × 10(−4)) and with Stage B endometriosis: two overlapping pathways that related to extracellular matrix biology—Core matrisome (P = 1.4 × 10(−3), FDR-P = 0.013) and ECM glycoproteins (P = 1.8 × 10(−3), FDR-P = 7.1 × 10(−3)). …”
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    Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis
  12. 2272
    “…DF is approved for the treatment of severe veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) complicating stem cell transplantation and has demonstrated efficacy and safety in critically ill patients with multi-organ failure, underpinned by vasculopathy, endotheliitis, immune activation and hemorrhagic risk (Richardson et al,Blood2016). …”
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    Defibrotide for the Treatment of Endotheliitis Complicating Sars-Cov-2 Infection: Rationale and Ongoing Studies As Part of the International Defacovid Study Group
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