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121
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122por Rombolá-Caldentey, Belén, Andrés, Zaida, Waadt, Rainer, Quintero, Francisco J., Schumacher, Karin, Pardo, José M.“…These pHcyt changes were substantially reduced in mutant roots lacking a functional SOS3/CBL4 protein, suggesting that the operation of the SOS pathway mediated the dynamics of pHcyt in response to salinity.…”
Publicado 2023
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123
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124“…The salt overly sensitive 1 (SOS1) gene encodes the plasma membrane Na(+)/H(+) antiporter, SOS1, that is mainly responsible for extruding Na(+) from the cytoplasm and reducing the Na(+) content in plants under salt stress and is considered a vital determinant in conferring salt tolerance to the plant. …”
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126por Wang, Yuhang, Pan, Chengcai, Chen, Qihao, Xie, Qing, Gao, Yiwei, He, Lingli, Li, Yue, Dong, Yanli, Jiang, Xingyu, Zhao, Yan“…Here, we report the structures of SOS1. SOS1 forms a homodimer, with each monomer composed of transmembrane and intracellular domains. …”
Publicado 2023
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127por Lin, Tongtong, Pan, Jiao, Gregory, Colin, Wang, Yaohai, Tincher, Clayton, Rivera, Caitlyn, Lynch, Michael, Long, Hongan, Zhang, Yu“…Such antibiotics increase the genome-wide mutation rate by introducing replication errors from the SOS response pathway or decreasing the efficiency of the DNA repair systems. …”
Publicado 2023
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128por Ruijs, Kees DM, Onwuteaka-Philipsen, Bregje D, van der Wal, Gerrit, Kerkhof, Ad JFM“…The sum scores of (sub)scales were correlated strongly to overall measures on suffering. CONCLUSION: The SOS-V is an instrument for measuring the unbearability of suffering in end-stage cancer patients with good content validity and psychometric properties, which is feasible to be used in practice. …”
Publicado 2009
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129“…Heterogenous expression is established primarily by stochastic factors and the binding affinity of LexA to SOS boxes.…”
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130Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS responsepor Butala, Matej, Klose, Daniel, Hodnik, Vesna, Rems, Ana, Podlesek, Zdravko, Klare, Johann P., Anderluh, Gregor, Busby, Stephen J. W., Steinhoff, Heinz-Jürgen, Žgur-Bertok, Darja“…Our aim was to understand how RecA filament formation at any chromosomal location can induce the SOS system, which could explain the mechanism for precise timing of induction of SOS genes. …”
Publicado 2011
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132por Hocquet, Didier, Llanes, Catherine, Thouverez, Michelle, Kulasekara, Hemantha D., Bertrand, Xavier, Plésiat, Patrick, Mazel, Didier, Miller, Samuel I.“…It has been previously established that integrase expression can be activated by the SOS response in vitro, leading to speculation that this is an important clinical mechanism of acquiring resistance. …”
Publicado 2012
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133por Bernier, Steve P., Lebeaux, David, DeFrancesco, Alicia S., Valomon, Amandine, Soubigou, Guillaume, Coppée, Jean-Yves, Ghigo, Jean-Marc, Beloin, Christophe“…We further demonstrated that ofloxacin tolerance was induced as a function of biofilm age, which was dependent on the SOS response. Our results therefore show that the SOS stress response induced in heterogeneous and nutrient-deprived biofilm microenvironments is a molecular mechanism leading to biofilm-specific high tolerance to the fluoroquinolone ofloxacin.…”
Publicado 2013
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134“…This activation is mediated by oncogenic K-Ras-dependent allosteric stimulation of Sos and confers a growth advantage to oncogenic K-Ras harboring cancer cells. …”
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135por Qu, Yingying, Chen, Qin, Lai, Xueping, Zhu, Changhong, Chen, Cheng, Zhao, Xian, Deng, Rong, Xu, Ming, Yuan, Haihua, Wang, Yanli, Yu, Jianxiu, Huang, Jian“…BACKGROUND: Grb2 (Growth factor receptor-bound protein 2) is a key adaptor protein in maintaining the ERK activity via linking Sos1 (Son of sevenless homolog 1) or other proteins to activated RTKs, such as EGFR. …”
Publicado 2014
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136“…Activation of the SOS response is regulated by a key repressor-protease, LexA, which undergoes autoproteolysis in the setting of stress, resulting in derepression of SOS genes. …”
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137“…The Escherichia coli (E. coli) SOS response is the largest, most complex, and best characterized bacterial network induced by DNA damage. …”
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138“…Using short-term competition experiments, we demonstrate that the SOS pathway increases competitive fitness in the presence of ciprofloxacin. …”
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139por Ishikawa, Satoru, Hayashi, Shimpei, Abe, Tadashi, Igura, Masato, Kuramata, Masato, Tanikawa, Hachidai, Iino, Manaka, Saito, Takashi, Ono, Yuji, Ishikawa, Tetsuya, Fujimura, Shigeto, Goto, Akitoshi, Takagi, Hiroki“…Genetic analyses revealed that a mutation in OsSOS2, which encodes a serine/threonine-protein kinase required for the salt overly sensitive (SOS) pathway in plants, is responsible for the decreased cesium (Cs) concentrations in lcs1. …”
Publicado 2017
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140por Jové, Thomas, Da Re, Sandra, Tabesse, Aurore, Gassama-Sow, Amy, Ploy, Marie-Cécile“…The regulation of intI and of Pc promoters has been extensively studied in class 1 integrons and the regulatory role of the SOS response on intI expression has been shown. …”
Publicado 2017
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