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15921por Schaaf, Hendrik Simon, Willemse, Marianne, Cilliers, Karien, Labadarios, Demetre, Maritz, Johannes Stephanus, Hussey, Gregory D, McIlleron, Helen, Smith, Peter, Donald, Peter Roderick“…METHODS: Fifty-four children, 21 human immunodeficiency virus-infected and 33 human immunodeficiency virus-uninfected, mean ages 3.73 and 4.05 years (P = 0.68), respectively, admitted to a tuberculosis hospital in Cape Town, South Africa with severe forms of tuberculosis were studied approximately 1 month and 4 months after commencing antituberculosis treatment. …”
Publicado 2009
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15922por Jewkes, Rachel, Christofides, Nicola, Vetten, Lisa, Jina, Ruxana, Sigsworth, Romi, Loots, Lizle“…Our findings raise important questions about the value of evidence that requires the use of forensic laboratories at a population level in countries like South Africa that have substantial inefficiencies in their police services. …”
Publicado 2009
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15923por le Roux, Stanzi M, Cotton, Mark F, Golub, Jonathan E, le Roux, David M, Workman, Lesley, Zar, Heather J“…The study was conducted at two tertiary paediatric care centres in Cape Town, South Africa. Over a 5 year period, we followed 324 HIV-infected children aged ≥ 8 weeks. …”
Publicado 2009
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15924“…The current HIV/AIDS scenario in India is quite grim with an estimated 2.4 million people living with HIV/AIDS (PLHA) in 2008, just behind South Africa and Nigeria. The anti-retroviral drugs (ARVs) remain the main stay of global HIV/AIDS treatment. …”
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15925por Dahab, Mison, Charalambous, Salome, Karstaedt, Alan S, Fielding, Katherine L, Hamilton, Robin, La Grange, Lettie, Churchyard, Gavin J, Grant, Alison D“…To help address this evidence gap, this observational cohort study examined baseline factors potentially predictive of poor treatment outcomes in two ART programmes in South Africa, with a particular focus on determinants of adherence. …”
Publicado 2010
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15926por Churchyard, Gavin J., Morgan, Cecilia, Adams, Elizabeth, Hural, John, Graham, Barney S., Moodie, Zoe, Grove, Doug, Gray, Glenda, Bekker, Linda-Gail, McElrath, M. Juliana, Tomaras, Georgia D., Goepfert, Paul, Kalams, Spyros, Baden, Lindsey R., Lally, Michelle, Dolin, Raphael, Blattner, William, Kalichman, Artur, Figueroa, J. Peter, Pape, Jean, Schechter, Mauro, Defawe, Olivier, De Rosa, Stephen C., Montefiori, David C., Nabel, Gary J., Corey, Lawrence, Keefer, Michael C.“…BACKGROUND: The safety and immunogenicity of a vaccine regimen consisting of a 6-plasmid HIV-1 DNA prime (envA, envB, envC, gagB, polB, nefB) boosted by a recombinant adenovirus serotype-5 (rAd5) HIV-1 with matching inserts was evaluated in HIV-seronegative participants from South Africa, United States, Latin America and the Caribbean. …”
Publicado 2011
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15927por Burn, John, Gerdes, Anne-Marie, Macrae, Finlay, Mecklin, Jukka-Pekka, Moeslein, Gabriela, Olschwang, Sylviane, Eccles, Diane, Evans, D Gareth, Maher, Eamonn R, Bertario, Lucio, Bisgaard, Marie-Luise, Dunlop, Malcolm G, Ho, Judy WC, Hodgson, Shirley V, Lindblom, Annika, Lubinski, Jan, Morrison, Patrick J, Murday, Victoria, Ramesar, Raj, Side, Lucy, Scott, Rodney J, Thomas, Huw JW, Vasen, Hans F, Barker, Gail, Crawford, Gillian, Elliott, Faye, Movahedi, Mohammad, Pylvanainen, Kirsi, Wijnen, Juul T, Fodde, Riccardo, Lynch, Henry T, Mathers, John C, Bishop, D Timothy“…FUNDING: European Union; Cancer Research UK; Bayer Corporation; National Starch and Chemical Co; UK Medical Research Council; Newcastle Hospitals trustees; Cancer Council of Victoria Australia; THRIPP South Africa; The Finnish Cancer Foundation; SIAK Switzerland; Bayer Pharma.…”
Publicado 2011
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15928por Ledwaba, Lotty, Tavel, Jorge A., Khabo, Paul, Maja, Patrick, Qin, Jing, Sangweni, Phumele, Liu, Xiao, Follmann, Dean, Metcalf, Julia A., Orsega, Susan, Baseler, Beth, Neaton, James D., Lane, H. Clifford“…METHODS: Pre-ART plasma from patients with advanced HIV in South Africa was used to measure hsCRP, IL-6 and D-dimer. …”
Publicado 2012
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15929por Lockman, Shahin, Hughes, Michael, Sawe, Fred, Zheng, Yu, McIntyre, James, Chipato, Tsungai, Asmelash, Aida, Rassool, Mohammed, Kimaiyo, Sylvester, Shaffer, Douglas, Hosseinipour, Mina, Mohapi, Lerato, Ssali, Francis, Chibowa, Margret, Amod, Farida, Halvas, Elias, Hogg, Evelyn, Alston-Smith, Beverly, Smith, Laura, Schooley, Robert, Mellors, John, Currier, Judith“…METHODS AND FINDINGS: In seven African countries (Botswana, Kenya, Malawi, South Africa, Uganda, Zambia, and Zimbabwe), 500 antiretroviral-naïve HIV-infected women with CD4<200 cells/mm(3) were enrolled into a two-arm randomized trial to initiate open-label ART with tenofovir (TDF)/emtricitabine (FTC) once/day plus either NVP (n = 249) or LPV/r (n = 251) twice/day, and followed for ≥48 weeks. …”
Publicado 2012
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15930por Steele, Andrew Duncan, Neuzil, Kathleen M, Cunliffe, Nigel A, Madhi, Shabir A, Bos, Pieter, Ngwira, Bagrey, Witte, Desiree, Todd, Stacy, Louw, Cheryl, Kirsten, Mari, Aspinall, Sanet, Van Doorn, Leen Jan, Bouckenooghe, Alain, Suryakiran, Pemmaraju V, Han, Htay Htay“…The human, G1P[8] rotavirus vaccine Rotarix™ significantly reduced severe rotavirus gastroenteritis episodes in a Phase III clinical trial conducted in infants in South Africa and Malawi. This paper examines rotavirus vaccine efficacy in preventing severe rotavirus gastroenteritis, during infancy, caused by the various G and P rotavirus types encountered during the first rotavirus-season. …”
Publicado 2012
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15931por Zachary, Dalila, Mwenge, Lawrence, Muyoyeta, Monde, Shanaube, Kwame, Schaap, Albertus, Bond, Virginia, Kosloff, Barry, de Haas, Petra, Ayles, Helen“…METHODS: This was a operational retrospective research of HIV testing and questionnaire data collected in 2010 as part of the ZAMSTAR (Zambia South Africa TB and AIDS reduction) study. Randomly sampled individuals in twelve communities were tested consecutively with OraQuick® test using oral fluid versus two blood-based rapid HIV tests, Determine® and Uni-Gold(TM). …”
Publicado 2012
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15932por Menzies, Nicolas A., Cohen, Ted, Lin, Hsien-Ho, Murray, Megan, Salomon, Joshua A.“…METHODS AND FINDINGS: We evaluated potential health and economic consequences of implementing Xpert in five southern African countries—Botswana, Lesotho, Namibia, South Africa, and Swaziland—where drug resistance and TB-HIV coinfection are prevalent. …”
Publicado 2012
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15933por Spiegel, Jerry M, Lockhart, Karen, Dyck, Carmen, Wilson, Andrea, O’Hara, Lyndsay, Yassi, Annalee“…Implementation in South Africa highlighted the special care needed to address power dynamics regarding both worker-employer relations (relevant to all occupational health settings) and North–south imbalances (common to all international interactions). …”
Publicado 2012
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15934por Phaswana-Mafuya, Nancy, Peltzer, Karl, Chirinda, Witness, Kose, Zamakayise, Hoosain, Ebrahim, Ramlagan, Shandir, Tabane, Cily, Davids, Adlai“…DESIGN: A national population-based cross-sectional survey, with a sample of 3,840 individuals aged 50 years and older, was completed in South Africa in 2008. Self-reported ratings of overall health and functioning were measured using a single self-reported health state covering nine health domains (used to generate the Study on Global Ageing and Adult Health (SAGE) composite health state score). …”
Publicado 2013
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15935por Biritwum, Richard B., Mensah, George, Minicuci, Nadia, Yawson, Alfred E., Naidoo, Nirmala, Chatterji, Somnath, Kowal, Paul“…METHODS: The World Health Organization's Study on global AGEing and adult health (SAGE) Wave 1 was conducted in China, Ghana, India, Russian Federation, Mexico, and South Africa between 2007 and 2010. SAGE Ghana Wave 1 was implemented in 2007/08 using face-to-face interviews in a nationally representative sample of persons aged 50-plus, along with a smaller cohort aged 18–49 years for comparison purposes. …”
Publicado 2013
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15936por Kaforou, Myrsini, Wright, Victoria J., Oni, Tolu, French, Neil, Anderson, Suzanne T., Bangani, Nonzwakazi, Banwell, Claire M., Brent, Andrew J., Crampin, Amelia C., Dockrell, Hazel M., Eley, Brian, Heyderman, Robert S., Hibberd, Martin L., Kern, Florian, Langford, Paul R., Ling, Ling, Mendelson, Marc, Ottenhoff, Tom H., Zgambo, Femia, Wilkinson, Robert J., Coin, Lachlan J., Levin, Michael“…METHODS AND FINDINGS: Adult case-control cohorts were established in South Africa and Malawi of HIV-infected or -uninfected individuals consisting of 584 patients with either TB (confirmed by culture of Mycobacterium tuberculosis [M.TB] from sputum or tissue sample in a patient under investigation for TB), OD (i.e., TB was considered in the differential diagnosis but then excluded), or healthy individuals with latent TB infection (LTBI). …”
Publicado 2013
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15937por Mnyani, Coceka N, Simango, Adonia, Murphy, Joshua, Chersich, Matthew, McIntyre, James A“…This study thus identified key patient factors for MTCT in a high HIV prevalence setting in Johannesburg, South Africa. Between November 2010 and May 2012, we conducted a case–control study among HIV-infected women with HIV-infected (cases) and uninfected (controls) infants diagnosed around six weeks of age as part of routine, early infant diagnosis. …”
Publicado 2014
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15938por Whitworth, Kristina W., Bornman, Riana M.S., Archer, Janet I., Kudumu, Mwenda O., Travlos, Gregory S., Wilson, Ralph E., Longnecker, Matthew P.“…Methods: The present analysis included 381 women enrolled in the Study of Women and Babies (SOWB) during 2010–2011, from eight South African villages in the Limpopo Province, South Africa. Indoor residual spraying (IRS) occurred in half of the villages. …”
Publicado 2014
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15939por Ettinger, Adrienne S, Bovet, Pascal, Plange-Rhule, Jacob, Forrester, Terrence E, Lambert, Estelle V, Lupoli, Nicola, Shine, James, Dugas, Lara R, Shoham, David, Durazo-Arvizu, Ramon A, Cooper, Richard S, Luke, Amy“…METHODS: Young adults (25–45 years) of African descent were enrolled (N = 500 from each site) in: Ghana, South Africa, Seychelles, Jamaica and the U.S.A. We randomly selected 150 blood samples (N = 30 from each site) to determine concentrations of selected metals (arsenic, cadmium, lead, mercury) in a subset of participants at baseline and to examine associations with cardiometabolic risk factors. …”
Publicado 2014
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15940“…Videos were uploaded from 13 countries around the globe (ie, Australia, Barbados, Belgium, Canada, Colombia, Kenya, New Zealand, Russia, South Africa, Spain, Ukraine, United Kingdom, United States). …”
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