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16201por Liang, Kang-Hao, Chiang, Pao-Yin, Ko, Shih-Han, Chou, Yu-Chi, Lu, Ruei-Min, Lin, Hsiu-Ting, Chen, Wan-Yu, Lin, Yi-Ling, Tao, Mi-Hua, Jan, Jia-Tsrong, Wu, Han-Chung“…Notably, several cocktails of our antibodies showed low IC(50) values (3.35–27.06 ng/ml) against the SARS-CoV-2 variant pseudoviruses including United Kingdom variant B.1.1.7 (Alpha), South Africa variant B.1.351 (Beta), Brazil variant P1 (Gamma), California variant B.1.429 (Epsilon), New York variant B.1.526 (Iota), and India variants, B.1.617.1 (Kappa) and B.1.617.2 (Delta). …”
Publicado 2021
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16202por Ebonwu, Joy, Lassaunière, Ria, Paximadis, Maria, Goosen, Mark, Strehlau, Renate, Gray, Glenda E., Kuhn, Louise, Tiemessen, Caroline T.“…A follow-on trial, HVTN702, of a similar vaccine candidate found no efficacy in South Africa, where the predominant population is polymorphic for only a single variant in the haplotype, c.134-96C>T (rs114945036). …”
Publicado 2021
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16203por Allali, Imane, Abotsi, Regina E., Tow, Lemese Ah., Thabane, Lehana, Zar, Heather J., Mulder, Nicola M., Nicol, Mark P.“…The country where most studies were conducted was South Africa (27/168), followed by Kenya (23/168) and Uganda (18/168). 26.8% (45/168) focused on diseases of significant public health concern in Africa. …”
Publicado 2021
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16204por Somefun, Oluwaseyi Dolapo, Casale, Marisa, Haupt Ronnie, Genevieve, Desmond, Chris, Cluver, Lucie, Sherr, Lorraine“…Most studies were conducted in Southern Africa, of which 32 jointly in South Africa and Uganda. The majority of interventions assessed for acceptability could be classified as HIV or HPV vaccine interventions (10), E-health (10), HIV testing interventions (8), support group interventions (7) and contraceptive interventions (6). …”
Publicado 2021
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16205“…Methods: We aimed to identify the prevalence and the correlation between serum hyponatremia (mild, moderate and severe) and/or hypoglycorrhachia in relation to clinical TBM features such as stage of disease, seizures and stroke in children diagnosed with definite and probable TBM, between 1985 and 2015, at Tygerberg Hospital, Cape town, South Africa. Results: The prevalence of hyponatremia was 344 out of 481 (71.5%) patients; 169 (49.1%) had mild hyponatremia, 146 (42.4%) moderate hyponatremia and 29 (8.4%) severe hyponatremia. …”
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16206“…PubMed, CINAHL, EMBASE, EBSCO, Ovid maternity and infant care databases, Cochrane Database of Systematic Reviews, Web of Science and SCOPUS were searched, using the keywords ‘anaemia’, ’haemoglobin’, ‘pregnancy’, ‘South Africa’. Risk of bias was conducted using the Hoy tool and the Doi plot and LFK ratio. …”
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16207“…However, the emerging variants of SARS-CoV-2, i.e., Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2) variants which evolved in late 2020 and the Omicron variant (B.1.1.529) which emerged in November 2021 along with its subvariant BA.2 which was first identified in India and South Africa in late December 2021, have raised the doubt about the efficiency of the currently used vaccines especially in terms of the consistent potential to produce neutralizing antibodies targeting the viral spike (S) protein. …”
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16208por Dunning, Lorna, Gandhi, Aditya R, Penazzato, Martina, Soeteman, Djøra I, Revill, Paul, Frank, Simone, Phillips, Andrew, Dugdale, Caitlin, Abrams, Elaine, Weinstein, Milton C, Newell, Marie‐Louise, Collins, Intira J, Doherty, Meg, Vojnov, Lara, Fassinou Ekouévi, Patricia, Myer, Landon, Mushavi, Angela, Freedberg, Kenneth A, Ciaranello, Andrea L“…METHODS: Using the CEPAC‐Pediatric model, we compared two strategies for infants born in 2017 in Côte d’Ivoire (CI), South Africa (SA), and Zimbabwe: (1) existing EID programmes offering six‐week nucleic acid testing (NAT) for infants with known HIV exposure (EID), and (2) EID plus universal maternal HIV screening at six‐week infant immunization visits, leading to referral for infant NAT and maternal ART initiation (screen‐and‐test). …”
Publicado 2021
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16209“…METHODS: Data were taken from the Mental Health Million open-access database (N=179,238) and included responses from English-speaking adults (aged≥18 years) from the United States, Canada, the United Kingdom, Ireland, Australia, New Zealand, South Africa, Singapore, India, and Nigeria collected during 2021. …”
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16210por van der Hoven, Jani, Allen, Elizabeth, Cois, Annibale, de Waal, Renee, Maartens, Gary, Myer, Landon, Malaba, Thokozile, Madlala, Hlengiwe, Nyemba, Dorothy, Phelanyane, Florence, Boulle, Andrew, Mehta, Ushma, Kalk, Emma“…We compared three methods to determine antenatal medicine use (self-report, clinician records and electronic pharmacy dispensing records [EDR]) in women attending antenatal care at a primary care facility in Cape Town, South Africa in a setting with high HIV prevalence. METHODS: Structured, interview-administered questionnaires recorded self-reported medicine use. …”
Publicado 2022
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16211“…METHODS: Five hundred and fifty children and adolescents, aged 8–15-years, with acute and chronic health conditions and a general population sample were recruited from schools and hospitals in Cape Town South Africa. All respondents self-completed the Y-5L, PedsQL, Self-Rated Health Question and Y-3L. …”
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16212por Matefo, Litabe, Cloete, van Vuuren, Armand, Bester Philip, Dominique, Goedhals, Samantha, Potgieter, John, Frater, Craig, Thompson, Daniel, Wright, Theresa, Lambe, Sunetra, Gupta, Maréza, Brink, Danelle, van Jaarsveldt, Jane, Burt Felicity“…The tests were compared with commercially available and South Africa Health Products Regulatory Authority (SAPHRA) approved assays. …”
Publicado 2022
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16213por Fernández-Luis, Sheila, Lain, Maria Grazia, Serna-Pascual, Miquel, Domínguez-Rodríguez, Sara, Kuhn, Louise, Liberty, Afaaf, Barnabas, Shaun, Lopez-Varela, Elisa, Otwombe, Kennedy, Danaviah, Siva, Nastouli, Eleni, Palma, Paolo, Cotugno, Nicola, Spyer, Moira, Giannuzzi, Viviana, Giaquinto, Carlo, Violari, Avy, Cotton, Mark F., Nhampossa, Tacilta, Klein, Nigel, Ramsagar, Nastassja, van Rensburg, Anita Janse, Behuhuma, Osee, Vaz, Paula, Maiga, Almoustapha Issiaka, Oletto, Andrea, Naniche, Denise, Rossi, Paolo, Rojo, Pablo, Tagarro, Alfredo“…METHODS: We used data from infants with perinatal HIV infection and their mothers enrolled from May-2018 to May-2020 in Mozambique, South Africa, and Mali. We retrospectively compared the performance of the WHO-algorithm with a modified algorithm which included mothers’ adherence as an additional factor. …”
Publicado 2022
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16214por Khan, Khadija, Karim, Farina, Cele, Sandile, Reedoy, Kajal, San, James Emmanuel, Lustig, Gila, Tegally, Houriiyah, Rosenberg, Yuval, Bernstein, Mallory, Jule, Zesuliwe, Ganga, Yashica, Ngcobo, Nokuthula, Mazibuko, Matilda, Mthabela, Ntombifuthi, Mhlane, Zoey, Mbatha, Nikiwe, Miya, Yoliswa, Giandhari, Jennifer, Ramphal, Yajna, Naidoo, Taryn, Sivro, Aida, Samsunder, Natasha, Kharsany, Ayesha B. M., Amoako, Daniel, Bhiman, Jinal N., Manickchund, Nithendra, Abdool Karim, Quarraisha, Magula, Nombulelo, Abdool Karim, Salim S., Gray, Glenda, Hanekom, Willem, von Gottberg, Anne, Milo, Ron, Gosnell, Bernadett I., Lessells, Richard J., Moore, Penny L., de Oliveira, Tulio, Moosa, Mahomed-Yunus S., Sigal, Alex“…Here we measured the neutralization capacity against variants of severe acute respiratory syndrome coronavirus 2 in 39 individuals in South Africa infected with the Omicron sublineage BA.1 starting at a median of 6 (interquartile range 3–9) days post symptom onset and continuing until last follow-up sample available, a median of 23 (interquartile range 19–27) days post symptoms to allow BA.1-elicited neutralizing immunity time to develop. …”
Publicado 2022
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16215por Ebonwu, Joy, Lassaunière, Ria, Paximadis, Maria, Strehlau, Renate, Gray, Glenda E., Kuhn, Louise, Tiemessen, Caroline T.“…METHODS: This nested case-control study combines FCGR genotypic data from three perinatal cohorts at two hospitals in Johannesburg, South Africa. Children with perinatally-acquired HIV-1 (cases, n = 395) were compared to HIV-1-exposed uninfected children (controls, n = 312). …”
Publicado 2022
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16216por Kolkenbeck-Ruh, Andrea, Soepnel, Larske M., Crouch, Simone H., Naidoo, Sanushka, Smith, Wayne, Norris, Shane A., Davies, Justine, Ware, Lisa J.“…METHODS: Black female adults (n = 123; age: 29–68 years) and their children (n = 64; age: 4–10; 55% female) were recruited from the Birth to Twenty Plus Cohort in Soweto, South Africa. Tobacco and alcohol use, physical activity, presence of diabetes mellitus, heart disease, and medication were self-reported. …”
Publicado 2022
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16217por Poester, Vanice, Munhoz, Lívia, Melo, Aryse, Benelli, Jéssica, Al-Hatmi, Abdullah, Larwood, David, Martinez, Marife, Stevens, David, Xavier, Melissa“…METHODS: A total of 11 isolates of C. auris were included in this in vitro study, 10 from South Asian clade I and 1 from South Africa clade III. In vitro tests (dilution and interaction assays) were performed according to the CLSI M27-Ed4 protocol. …”
Publicado 2022
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16218por Asiimwe, Innocent G., Blockman, Marc, Cohen, Karen, Cupido, Clint, Hutchinson, Claire, Jacobson, Barry, Lamorde, Mohammed, Morgan, Jennie, Mouton, Johannes P., Nakagaayi, Doreen, Okello, Emmy, Schapkaitz, Elise, Sekaggya-Wiltshire, Christine, Semakula, Jerome R., Waitt, Catriona, Zhang, Eunice J., Jorgensen, Andrea L., Pirmohamed, Munir“…Participants recruited at 12 outpatient sites in Uganda and South Africa on stable warfarin dose were genotyped using the Illumina Infinium H3Africa Consortium Array v2. …”
Publicado 2022
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16219“…The Omicron variant was first reported to the World Health Organization (WHO) from South Africa on November 24, 2021; this variant is spreading rapidly worldwide. …”
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16220por Steventon Roberts, Kathryn J., Smith, Colette, Cluver, Lucie, Toska, Elona, Jochim, Janina, Wittesaele, Camille, Marlow, Marguerite, Sherr, Lorraine“…METHODS: Cross-sectional data utilised within the analyses was drawn from a large cohort of adolescent mothers and their children residing in South Africa. Detailed study questionnaires were completed by adolescent mothers relating to their self and their child and, standardised cognitive assessments were completed by trained researchers for all children using in the Mullen Scales of Early Learning. …”
Publicado 2022
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