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16281por Bohren, Meghan A., Lorencatto, Fabiana, Coomarasamy, Arri, Althabe, Fernando, Devall, Adam J., Evans, Cherrie, Oladapo, Olufemi T., Lissauer, David, Akter, Shahinoor, Forbes, Gillian, Thomas, Eleanor, Galadanci, Hadiza, Qureshi, Zahida, Fawcus, Sue, Hofmeyr, G. Justus, Al-beity, Fadhlun Alwy, Kasturiratne, Anuradhani, Kumarendran, Balachandran, Mammoliti, Kristie-Marie, Vogel, Joshua P., Gallos, Ioannis, Miller, Suellen“…METHODS: We will use behavior change and implementation science frameworks [e.g. capability, opportunity, motivation and behavior (COM-B) and theoretical domains framework (TDF)] to guide data collection and analysis, in Kenya, Nigeria, South Africa, Sri Lanka, and Tanzania. There are four methodological components: qualitative interviews; surveys; systematic reviews; and design workshops. …”
Publicado 2021
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16282por Amusa, Lateef, Zewotir, Temesgen, North, Delia, Kharsany, Ayesha B. M., Lewis, Lara“…We investigated the associations between MMC and these STI outcomes, using cross-sectional data from the HIV Incidence Provincial Surveillance System (HIPSS) study in KwaZulu-Natal, South Africa. HIV antibodies were tested from the blood samples collected in the study. …”
Publicado 2021
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16283por Riou, Julien, Dupont, Carole, Bertagnolio, Silvia, Gupta, Ravindra K., Kouyos, Roger D., Egger, Matthias, L. Althaus, Christian“…The fragility index was low in Botswana (0.01; 0.0–0.11) but high in Namibia (0.48; 0.16–10.17), Eswatini (0.64; 0.23–11.8) and South Africa (1.21; 0.83–9.84). The combination of high fragility of ART programmes and high ART coverage levels was associated with a sharp increase in pretreatment NNRTI resistance. …”
Publicado 2021
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16284por Dheda, K, Charalambous, S, Karat, A S, von Delft, A, Lalloo, U G, van Zyl Smit, R, Perumal, R, Allwood, B W, Esmail, A, Wong, M L, Duse, A G, Richards, G, Feldman, C, Mer, M, Nyamande, K, Lalla, U, Koegelenberg, C F N, Venter, F, Dawood, H, Adams, S, Ntusi, N A B, van der Westhuizen, H-M, Moosa, M-Y S, Martinson, N A, Moultrie, H, Nel, J, Hausler, H, Preiser, W, Lasersohn, L, Zar, H J, Churchyard, G J“…N95 masks) are more effective than surgical masks against bio-aerosols, many international organisations now recommend that health workers (HWs) wear a respirator when caring for individuals who may have COVID-19. In South Africa (SA), however, surgical masks are still recommended for the routine care of individuals with possible or confirmed COVID-19, with respirators reserved for so-called aerosol-generating procedures. …”
Publicado 2021
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16285“…In addition, five controls comprised of synthetic RNA B.1.1.7_601443, B.1.351_678597, P.1_792683, B.1.617.1_1662307 and MN908947.3-Wuhan-hu-1 from Twist bioscience and B.1.1.7 (England/204820464/2020) and B.1.351 (South Africa/KRISP-K005325/2020) from Zeptometrix, NY, USA were used for validation. …”
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16286por Lamb, Karen E., Crawford, David, Thornton, Lukar E., Shariful Islam, Sheikh M., Maddison, Ralph, Ball, Kylie“…METHODS: Cross-sectional data for 31,780 participants from China, Ghana, India, Mexico, Russia, and South Africa from the World Health Organization Study on Global AGEing and adult health (SAGE) study were used. …”
Publicado 2021
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16287por Acharya, Arpan, Pandey, Kabita, Thurman, Michellie, Klug, Elizabeth, Trivedi, Jay, Sharma, Kalicharan, Lorson, Christian L., Singh, Kamal, Byrareddy, Siddappa N.“…Out of the five, two compounds (MU-UNMC-1 and MU-UNMC-2) have antiviral activity against ancestral SARS-CoV-2 and emerging variants from South Africa and Scotland. Furthermore, MU-UNMC-2 acts synergistically with remdesivir (RDV), suggesting that RDV and MU-UNMC-2 can be developed as a combination therapy to treat COVID-19 patients.…”
Publicado 2021
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16288por Donenberg, Geri, Merrill, Katherine G., Atujuna, Millicent, Emerson, Erin, Bray, Bethany, Bekker, Linda Gail“…This study presents findings from a pilot test of an empirically supported culturally adapted family-based HIV-prevention program, Informed Motivated Aware and Responsible Adolescents and Adults- South Africa (IMARA-SA), on AGYW anxiety, depression, and trauma. …”
Publicado 2021
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16289por Vasileiou, Spyridoula, Kuvalekar, Manik, Workineh, Aster, Watanabe, Ayumi, Velazquez, Yovana, Lulla, Suhasini, Heslop, Helen Elisabeth, Mooney, Kimberly, Grimes, Kevin, Carrum, George, Hill, LaQuisa, Lulla, Premal, Leen, Ann Marie“…Finally, though initially generated against the reference strain NC_045512.2 (Wuhan), these VSTs were able to recognize other clinically important variants including B1.1.7 (UK), B1.351 (South Africa) and P1 (Brazil). This demonstrates the cross-reactive potential of these polyclonal and diverse VSTs, which were developed to provide potent antiviral effects and minimize the risk of immune escape due to sequence variation. …”
Publicado 2021
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16290por Rochat, Tamsen J., Dube, Samukelisiwe, Herbst, Kobus, Hoegfeldt, Cecilia A., Redinger, Stephanie, Khoza, Thandeka, Bland, Ruth Margret, Richter, Linda, Linsell, Louise, Desmond, Chris, Yousafzai, Aisha K., Craske, Michelle, Juszczak, Ed, Abas, Melanie, Edwards, Taygen, Ekers, David, Stein, Alan“…A total of 528 pregnant HIV-positive women aged ≥ 16 years who meet the criteria for depression on the Edinburgh Postnatal Depression Scale (EPDS, score ≥ 9)) are recruited from antenatal clinics in rural KwaZulu-Natal, South Africa. The geospatial clusters are randomised on an allocation ratio of 1:1 to either the intervention or Enhanced Standard of Care (ESoC). …”
Publicado 2021
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16291por Dunkle, Lisa M., Kotloff, Karen L., Gay, Cynthia L., Áñez, Germán, Adelglass, Jeffrey M., Barrat Hernández, Alejandro Q., Harper, Wayne L., Duncanson, Daniel M., McArthur, Monica A., Florescu, Diana F., McClelland, R. Scott, Garcia-Fragoso, Veronica, Riesenberg, Robert A., Musante, David B., Fried, David L., Safirstein, Beth E., McKenzie, Mark, Jeanfreau, Robert J., Kingsley, Jeffrey K., Henderson, Jeffrey A., Lane, Dakotah C., Ruíz-Palacios, Guillermo M., Corey, Lawrence, Neuzil, Kathleen M., Coombs, Robert W., Greninger, Alex L., Hutter, Julia, Ake, Julie A., Smith, Katherine, Woo, Wayne, Cho, Iksung, Glenn, Gregory M., Dubovsky, Filip“…BACKGROUND: NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle vaccine that was shown to have clinical efficacy for the prevention of coronavirus disease 2019 (Covid-19) in phase 2b–3 trials in the United Kingdom and South Africa, but its efficacy had not yet been tested in North America. …”
Publicado 2021
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16292por Eksteen, Susan, Eikelboom, Robert H., Kuper, Hannah, Launer, Stefan, Swanepoel, De Wet“…Follow-up assessments were conducted using smartphones that host point-of-care validated and calibrated hearing and vision testing applications (hearTest app, hearX Group, South Africa and PeekAcuity app, Peek Vision, United Kingdom). …”
Publicado 2022
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16293por Mwansa-Kambafwile, Judith R. M., Chasela, Charles, Levin, Jonathan, Ismail, Nazir, Menezes, Colin“…BACKGROUND: In South Africa, tuberculosis (TB) is a public health problem with treatment initiation failure rates varying between 14.9 and 25%. …”
Publicado 2022
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16294“…In addition, five controls comprised of synthetic RNA B.1.1.7_601443, B.1.351_678597, B.1.351_678597, P.1_792683, B.1.617.1_1662307 and MN908947.3-Wuhan-hu-1 from Twist bioscience and B.1.1.7 (England/204820464/2020) and B.1.351 (South Africa/KRISP-K005325/2020) from (Zeptometrix, NY, USA) were used for validation. …”
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16295por Chasimpha, Steady, McCormack, Valerie, Cubasch, Herbert, Joffe, Maureen, Zietsman, Annelle, Galukande, Moses, Parham, Groesbeck, Pinder, Leeya F, Anele, Angelica, Adisa, Charles A, Offiah, Awa Ukonye, Anderson, Benjamin O, Boucheron, Pauline, Foerster, Milena, Schüz, Joachim, dos-Santos-Silva, Isabel“…METHODS: The African Breast Cancer–Disparities in Outcomes (ABC-DO) study is a prospective cohort of women (aged ≥18 years) with incident breast cancer recruited consecutively at diagnosis (2014–17) from hospitals in Namibia, Nigeria, South Africa, Uganda, and Zambia. Detailed clinical and epidemiological data, including self-reported or tested HIV status, were collected at baseline. …”
Publicado 2022
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16296por Rao, Aditi, Chen, Victoria H., Hill, Sarah, Reynolds, Steven J., Redd, Andrew D., Stead, David, Hoffmann, Christopher, Quinn, Thomas C., Hansoti, Bhakti“…METHODS: This is a pre-and-post study design measuring the effect of a new ED-based HCT intervention, conducted by lay counsellors, on provider attitudes in Eastern Cape, South Africa. A validated, anonymized, 7-item survey was self-completed by routine care providers (physicians, nurses, and case managers). …”
Publicado 2022
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16297por Berry, Catherine, du Cros, Philipp, Fielding, Katherine, Gajewski, Suzanne, Kazounis, Emil, McHugh, Timothy D., Merle, Corinne, Motta, Ilaria, Moore, David A. J., Nyang’wa, Bern-Thomas“…Conducted in Uzbekistan, South Africa and Belarus, patients aged 15 and above with rifampicin-resistant pulmonary tuberculosis and requiring a new course of therapy were eligible for inclusion irrespective of HIV status. …”
Publicado 2022
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16298por Teng, Ai-Ying, Che, Tian-Le, Zhang, An-Ran, Zhang, Yuan-Yuan, Xu, Qiang, Wang, Tao, Sun, Yan-Qun, Jiang, Bao-Gui, Lv, Chen-Long, Chen, Jin-Jin, Wang, Li-Ping, Hay, Simon I., Liu, Wei, Fang, Li-Qun“…We further identified three cities including Guangzhou, Beijing and Shanghai, with the highest imported risk of RVFV potentially from Egypt, South Africa, Saudi Arabia and Kenya. CONCLUSIONS: A variety of Bunyavirales viruses are widely distributed in China, and the two major neglected Bunyavirales viruses including CCHFV and RVFV, both have the potential for outbreaks in local areas of China. …”
Publicado 2022
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16299por Belay, Daniel Gashaneh, Aragaw, Fantu Mamo, Teklu, Rediet Eristu, Fetene, Samrawit Mihret, Negash, Wubshet Debebe, Asmamaw, Desale Bihonegn, Fentie, Elsa Awoke, Alemu, Tewodros Getaneh, Eshetu, Habitu Birhan, Shewarega, Ever Siyoum“…RESULTS: The pooled magnitude of inadequate MDD intake among children aged 6–23 months in SSA was 76.53% (95% CI: 73.37, 79.70), ranging from 50.5% in South Africa to 94.40% in Burkina Faso. Individual-level factors such as women having secondary and above education (AOR = 0.66; 95% CI; 0.62, 0.70), being employed (AOR = 0.76; 95% CI; 0.72, 0.79), having household media exposure (AOR = 0.69; 95% CI; 0.66, 0.72), richest wealth (AOR = 0.46; 95% CI; 0.43, 0.50), having health institution delivery (AOR = 0.87;95% CI; 0.83, 0.91), and community-level factor such as living in upper middle-income country (AOR = 0.42; 95% CI; 0.38, 0.46) had a significant protective association, whereas rural residence (AOR = 1.29; 95% CI; 1.23, 1.36) has a significant positive association with inadequate MDD intake among children aged 6–23 months. …”
Publicado 2022
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16300por Closson, Kalysha, Zharima, Campion, Kuchena, Michelle, Dietrich, Janan J., Gadermann, Anne, Ogilvie, Gina, Beksinska, Mags, Kaida, Angela“…RESULTS: Overall, 21 women and 17 men aged 21–30 participated in CIs in Durban and Soweto, South Africa. Cognitive Coding revealed 1. Comprehension issues, and 2. …”
Publicado 2022
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