TUXEDO: a phase I/II trial of cetuximab with chemoradiotherapy in muscle‐invasive bladder cancer

por James, Nicholas D., Liu, Wenyu, Pirrie, Sarah, Kaur, Baljit, Hendron, Carey, Ford, Daniel, Zarkar, Anjali, Viney, Richard, Southgate, Elizabeth, Desai, Amisha, Hussain, Syed A., Barber, Jim, Syndikus, Isabel, Malik, Zafar, Eswar, Chinnamani, Mangar, Stephen, Money‐Kyrle, Julian, Lydon, Anna, Van Der Voet, Johannes, James, Nicholas, Zarkar, Anjali, Ford, Dan
Publicado 2022

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein

por Dewari, Pooran Singh, Southgate, Benjamin, Mccarten, Katrina, Monogarov, German, O'Duibhir, Eoghan, Quinn, Niall, Tyrer, Ashley, Leitner, Marie-Christin, Plumb, Colin, Kalantzaki, Maria, Blin, Carla, Finch, Rebecca, Bressan, Raul Bardini, Morrison, Gillian, Jacobi, Ashley M, Behlke, Mark A, von Kriegsheim, Alex, Tomlinson, Simon, Krijgsveld, Jeroen, Pollard, Steven M
Publicado 2018

Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension

por Ulrich, Anna, Wharton, John, Thayer, Timothy E., Swietlik, Emilia M., Assad, Tufik R., Desai, Ankit A., Gräf, Stefan, Harbaum, Lars, Humbert, Marc, Morrell, Nicholas W., Nichols, William C., Soubrier, Florent, Southgate, Laura, Trégouët, David-Alexandre, Trembath, Richard C., Brittain, Evan L., Wilkins, Martin R., Prokopenko, Inga, Rhodes, Christopher J.
Publicado 2020

Can UK healthcare workers remotely support medical education in the developing world?: Focus group evaluation

por Bowen, JST, Southgate, RJ, Ali, AM, Little, SJ, Liakos, A, Greaves, F, Strachan, JM, Baraco, AFH, Adem, G, Abdillahi, M, Handuleh, J, Reed, K, Walker, F, Zeron, J, Strachan, M, Bowen, S, Hellyer, T, Hersheson, J, Whitwell, S, Fyfe, M, Phillips, JC, Trim, C, Johnson, O, Leather, AJM, Al-Hadithy, N, Finlayson, AET
Publicado 2012

Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

por Darlow, John M., Darlay, Rebecca, Dobson, Mark G., Stewart, Aisling, Charoen, Pimphen, Southgate, Jennifer, Baker, Simon C., Xu, Yaobo, Hunziker, Manuela, Lambert, Heather J., Green, Andrew J., Santibanez-Koref, Mauro, Sayer, John A., Goodship, Timothy H. J., Puri, Prem, Woolf, Adrian S., Kenda, Rajko B., Barton, David E., Cordell, Heather J.
Publicado 2017

Publisher Correction: Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

por Darlow, John M., Darlay, Rebecca, Dobson, Mark G., Stewart, Aisling, Charoen, Pimphen, Southgate, Jennifer, Baker, Simon C., Xu, Yaobo, Hunziker, Manuela, Lambert, Heather J., Green, Andrew J., Santibanez-Koref, Mauro, Sayer, John A., Goodship, Timothy H. J., Puri, Prem, Woolf, Adrian S., Kenda, Rajko B., Barton, David E., Cordell, Heather J.
Publicado 2018

Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper

por Illuzzi, Giuditta, Staniszewska, Anna D., Gill, Sonja J., Pike, Andy, McWilliams, Lisa, Critchlow, Susan E., Cronin, Anna, Fawell, Stephen, Hawthorne, Glen, Jamal, Kunzah, Johannes, Jeffrey, Leonard, Emilyanne, Macdonald, Ruth, Maglennon, Gareth, Nikkilä, Jenni, O'Connor, Mark J., Smith, Aaron, Southgate, Harriet, Wilson, Joanne, Yates, James, Cosulich, Sabina, Leo, Elisabetta
Publicado 2022

CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

por Nicholls, Samuel M., Poplawski, Radoslaw, Bull, Matthew J., Underwood, Anthony, Chapman, Michael, Abu-Dahab, Khalil, Taylor, Ben, Colquhoun, Rachel M., Rowe, Will P. M., Jackson, Ben, Hill, Verity, O’Toole, Áine, Rey, Sara, Southgate, Joel, Amato, Roberto, Livett, Rich, Gonçalves, Sónia, Harrison, Ewan M., Peacock, Sharon J., Aanensen, David M., Rambaut, Andrew, Connor, Thomas R., Loman, Nicholas J.
Publicado 2021

Biallelic variants of ATP13A3 cause dose-dependent childhood-onset pulmonary arterial hypertension characterised by extreme morbidity and mortality

por Machado, Rajiv D, Welch, Carrie L, Haimel, Matthias, Bleda, Marta, Colglazier, Elizabeth, Coulson, John D, Debeljak, Marusa, Ekstein, Josef, Fineman, Jeffrey R, Golden, William Christopher, Griffin, Emily L, Hadinnapola, Charaka, Harris, Michael A, Hirsch, Yoel, Hoover-Fong, Julie Elizabeth, Nogee, Lawrence, Romer, Lewis H, Vesel, Samo, Gräf, Stefan, Morrell, Nicholas W, Southgate, Laura, Chung, Wendy K
Publicado 2022

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

por Gangoso, Ester, Southgate, Benjamin, Bradley, Leanne, Rus, Stefanie, Galvez-Cancino, Felipe, McGivern, Niamh, Güç, Esra, Kapourani, Chantriolnt-Andreas, Byron, Adam, Ferguson, Kirsty M., Alfazema, Neza, Morrison, Gillian, Grant, Vivien, Blin, Carla, Sou, IengFong, Marques-Torrejon, Maria Angeles, Conde, Lucia, Parrinello, Simona, Herrero, Javier, Beck, Stephan, Brandner, Sebastian, Brennan, Paul M., Bertone, Paul, Pollard, Jeffrey W., Quezada, Sergio A., Sproul, Duncan, Frame, Margaret C., Serrels, Alan, Pollard, Steven M.
Publicado 2021

The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK

por Hill, Verity, Du Plessis, Louis, Peacock, Thomas P, Aggarwal, Dinesh, Colquhoun, Rachel, Carabelli, Alesandro M, Ellaby, Nicholas, Gallagher, Eileen, Groves, Natalie, Jackson, Ben, McCrone, J T, O’Toole, Áine, Price, Anna, Sanderson, Theo, Scher, Emily, Southgate, Joel, Volz, Erik, Barclay, Wendy S, Barrett, Jeffrey C, Chand, Meera, Connor, Thomas, Goodfellow, Ian, Gupta, Ravindra K, Harrison, Ewan M, Loman, Nicholas, Myers, Richard, Robertson, David L, Pybus, Oliver G, Rambaut, Andrew
Publicado 2022

Correction: A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome

por Cuvertino, Sara, Hartill, Verity, Colyer, Alice, Garner, Terence, Nair, Nisha, Al-Gazali, Lihadh, Canham, Natalie, Faundes, Victor, Flinter, Frances, Hertecant, Jozef, Holder-Espinasse, Muriel, Jackson, Brian, Lynch, Sally Ann, Nadat, Fatima, Narasimhan, Vagheesh M., Peckham, Michelle, Sellers, Robert, Seri, Marco, Montanari, Francesca, Southgate, Laura, Squeo, Gabriella Maria, Trembath, Richard, van Heel, David, Venuto, Santina, Weisberg, Daniel, Stals, Karen, Ellard, Sian, Barton, Anne, Kimber, Susan J., Sheridan, Eamonn, Merla, Giuseppe, Stevens, Adam, Johnson, Colin A., Banka, Siddharth
Publicado 2020

A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome

por Cuvertino, Sara, Hartill, Verity, Colyer, Alice, Garner, Terence, Nair, Nisha, Al-Gazali, Lihadh, Canham, Natalie, Faundes, Victor, Flinter, Frances, Hertecant, Jozef, Holder-Espinasse, Muriel, Jackson, Brian, Lynch, Sally Ann, Nadat, Fatima, Narasimhan, Vagheesh M., Peckham, Michelle, Sellers, Robert, Seri, Marco, Montanari, Francesca, Southgate, Laura, Squeo, Gabriella Maria, Trembath, Richard, van Heel, David, Venuto, Santina, Weisberg, Daniel, Stals, Karen, Ellard, Sian, Barton, Anne, Kimber, Susan J., Sheridan, Eamonn, Merla, Giuseppe, Stevens, Adam, Johnson, Colin A., Banka, Siddharth
Publicado 2020

Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome

por Rhodes, Christopher J., Otero-Núñez, Pablo, Wharton, John, Swietlik, Emilia M., Kariotis, Sokratis, Harbaum, Lars, Dunning, Mark J., Elinoff, Jason M., Errington, Niamh, Thompson, A. A. Roger, Iremonger, James, Coghlan, J. Gerry, Corris, Paul A., Howard, Luke S., Kiely, David G., Church, Colin, Pepke-Zaba, Joanna, Toshner, Mark, Wort, Stephen J., Desai, Ankit A., Humbert, Marc, Nichols, William C., Southgate, Laura, Trégouët, David-Alexandre, Trembath, Richard C., Prokopenko, Inga, Gräf, Stefan, Morrell, Nicholas W., Wang, Dennis, Lawrie, Allan
Publicado 2020

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

por Volz, Erik, Hill, Verity, McCrone, John T., Price, Anna, Jorgensen, David, O’Toole, Áine, Southgate, Joel, Johnson, Robert, Jackson, Ben, Nascimento, Fabricia F., Rey, Sara M., Nicholls, Samuel M., Colquhoun, Rachel M., da Silva Filipe, Ana, Shepherd, James, Pascall, David J., Shah, Rajiv, Jesudason, Natasha, Li, Kathy, Jarrett, Ruth, Pacchiarini, Nicole, Bull, Matthew, Geidelberg, Lily, Siveroni, Igor, Goodfellow, Ian, Loman, Nicholas J., Pybus, Oliver G., Robertson, David L., Thomson, Emma C., Rambaut, Andrew, Connor, Thomas R.
Publicado 2021

Elucidating the genetic architecture of Adams–Oliver syndrome in a large European cohort

por Meester, Josephina A.N., Sukalo, Maja, Schröder, Kim C., Schanze, Denny, Baynam, Gareth, Borck, Guntram, Bramswig, Nuria C., Duman, Duygu, Gilbert‐Dussardier, Brigitte, Holder‐Espinasse, Muriel, Itin, Peter, Johnson, Diana S., Joss, Shelagh, Koillinen, Hannele, McKenzie, Fiona, Morton, Jenny, Nelle, Heike, Reardon, Willie, Roll, Claudia, Salih, Mustafa A., Savarirayan, Ravi, Scurr, Ingrid, Splitt, Miranda, Thompson, Elizabeth, Titheradge, Hannah, Travers, Colm P., Van Maldergem, Lionel, Whiteford, Margo, Wieczorek, Dagmar, Vandeweyer, Geert, Trembath, Richard, Van Laer, Lut, Loeys, Bart L., Zenker, Martin, Southgate, Laura, Wuyts, Wim
Publicado 2018

Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension

por Swietlik, Emilia M., Greene, Daniel, Zhu, Na, Megy, Karyn, Cogliano, Marcella, Rajaram, Smitha, Pandya, Divya, Tilly, Tobias, Lutz, Katie A., Welch, Carrie C.L., Pauciulo, Michael W., Southgate, Laura, Martin, Jennifer M., Treacy, Carmen M., Penkett, Christopher J., Stephens, Jonathan C., Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Coleman, Anna W., Condliffe, Robin, Eichstaedt, Christina A., Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Girerd, Barbara, Grünig, Ekkehard, Holden, Simon, Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, Lordan, Jim, Machado, Rajiv D., MacKenzie Ross, Robert V., McCabe, Colm, Moledina, Shahin, Montani, David, Olschewski, Horst, Pepke-Zaba, Joanna, Price, Laura, Rhodes, Christopher J., Seeger, Werner, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark R., Vonk Noordegraaf, Anton, Wharton, John, Wild, James M., Wort, Stephen John, Lawrie, Allan, Wilkins, Martin R., Trembath, Richard C., Shen, Yufeng, Chung, Wendy K., Swift, Andrew J., Nichols, William C., Morrell, Nicholas W., Gräf, Stefan
Publicado 2020

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

por Gräf, Stefan, Haimel, Matthias, Bleda, Marta, Hadinnapola, Charaka, Southgate, Laura, Li, Wei, Hodgson, Joshua, Liu, Bin, Salmon, Richard M., Southwood, Mark, Machado, Rajiv D., Martin, Jennifer M., Treacy, Carmen M., Yates, Katherine, Daugherty, Louise C., Shamardina, Olga, Whitehorn, Deborah, Holden, Simon, Aldred, Micheala, Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A., Danesino, Cesare, Eyries, Mélanie, Gall, Henning, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J. Simon R., Girerd, Barbara, Houweling, Arjan C., Howard, Luke, Humbert, Marc, Kiely, David G., Kovacs, Gabor, MacKenzie Ross, Robert V., Moledina, Shahin, Montani, David, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Peacock, Andrew J., Pepke-Zaba, Joanna, Prokopenko, Inga, Rhodes, Christopher J., Scelsi, Laura, Seeger, Werner, Soubrier, Florent, Stein, Dan F., Suntharalingam, Jay, Swietlik, Emilia M., Toshner, Mark R., van Heel, David A., Vonk Noordegraaf, Anton, Waisfisz, Quinten, Wharton, John, Wort, Stephen J., Ouwehand, Willem H., Soranzo, Nicole, Lawrie, Allan, Upton, Paul D., Wilkins, Martin R., Trembath, Richard C., Morrell, Nicholas W.
Publicado 2018

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

por Rhodes, Christopher J, Batai, Ken, Bleda, Marta, Haimel, Matthias, Southgate, Laura, Germain, Marine, Pauciulo, Michael W, Hadinnapola, Charaka, Aman, Jurjan, Girerd, Barbara, Arora, Amit, Knight, Jo, Hanscombe, Ken B, Karnes, Jason H, Kaakinen, Marika, Gall, Henning, Ulrich, Anna, Harbaum, Lars, Cebola, Inês, Ferrer, Jorge, Lutz, Katie, Swietlik, Emilia M, Ahmad, Ferhaan, Amouyel, Philippe, Archer, Stephen L, Argula, Rahul, Austin, Eric D, Badesch, David, Bakshi, Sahil, Barnett, Christopher, Benza, Raymond, Bhatt, Nitin, Bogaard, Harm J, Burger, Charles D, Chakinala, Murali, Church, Colin, Coghlan, John G, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Debette, Stéphanie, Elliott, C Gregory, Elwing, Jean, Eyries, Melanie, Fortin, Terry, Franke, Andre, Frantz, Robert P, Frost, Adaani, Garcia, Joe G N, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Harley, John, He, Hua, Hill, Nicholas S, Hirsch, Russel, Houweling, Arjan C, Howard, Luke S, Ivy, Dunbar, Kiely, David G, Klinger, James, Kovacs, Gabor, Lahm, Tim, Laudes, Matthias, Machado, Rajiv D, MacKenzie Ross, Robert V, Marsolo, Keith, Martin, Lisa J, Moledina, Shahin, Montani, David, Nathan, Steven D, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Oudiz, Ronald J, Ouwehand, Willem H, Peacock, Andrew J, Pepke-Zaba, Joanna, Rehman, Zia, Robbins, Ivan, Roden, Dan M, Rosenzweig, Erika B, Saydain, Ghulam, Scelsi, Laura, Schilz, Robert, Seeger, Werner, Shaffer, Christian M, Simms, Robert W, Simon, Marc, Sitbon, Olivier, Suntharalingam, Jay, Tang, Haiyang, Tchourbanov, Alexander Y, Thenappan, Thenappan, Torres, Fernando, Toshner, Mark R, Treacy, Carmen M, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Walsworth, Anna K, Walter, Robert E, Wharton, John, White, R James, Wilt, Jeffrey, Wort, Stephen J, Yung, Delphine, Lawrie, Allan, Humbert, Marc, Soubrier, Florent, Trégouët, David-Alexandre, Prokopenko, Inga, Kittles, Richard, Gräf, Stefan, Nichols, William C, Trembath, Richard C, Desai, Ankit A, Morrell, Nicholas W, Wilkins, Martin R
Publicado 2019

Expert range maps of global mammal distributions harmonised to three taxonomic authorities

por Marsh, Charles J., Sica, Yanina V., Burgin, Connor J., Dorman, Wendy A., Anderson, Robert C., del Toro Mijares, Isabel, Vigneron, Jessica G., Barve, Vijay, Dombrowik, Victoria L., Duong, Michelle, Guralnick, Robert, Hart, Julie A., Maypole, J. Krish, McCall, Kira, Ranipeta, Ajay, Schuerkmann, Anna, Torselli, Michael A., Lacher, Thomas, Mittermeier, Russell A., Rylands, Anthony B., Sechrest, Wes, Wilson, Don E., Abba, Agustín M., Aguirre, Luis F., Arroyo‐Cabrales, Joaquín, Astúa, Diego, Baker, Andrew M., Braulik, Gill, Braun, Janet K., Brito, Jorge, Busher, Peter E., Burneo, Santiago F., Camacho, M. Alejandra, Cavallini, Paolo, de Almeida Chiquito, Elisandra, Cook, Joseph A., Cserkész, Tamás, Csorba, Gábor, Cuéllar Soto, Erika, da Cunha Tavares, Valeria, Davenport, Tim R. B., Deméré, Thomas, Denys, Christiane, Dickman, Christopher R., Eldridge, Mark D. B., Fernandez‐Duque, Eduardo, Francis, Charles M., Frankham, Greta, Franklin, William L., Freitas, Thales, Friend, J. Anthony, Gadsby, Elizabeth L., Garbino, Guilherme S. T., Gaubert, Philippe, Giannini, Norberto, Giarla, Thomas, Gilchrist, Jason S., Gongora, Jaime, Goodman, Steven M., Gursky‐Doyen, Sharon, Hackländer, Klaus, Hafner, Mark S., Hawkins, Melissa, Helgen, Kristofer M., Heritage, Steven, Hinckley, Arlo, Hintsche, Stefan, Holden, Mary, Holekamp, Kay E., Honeycutt, Rodney L., Huffman, Brent A., Humle, Tatyana, Hutterer, Rainer, Ibáñez Ulargui, Carlos, Jackson, Stephen M., Janecka, Jan, Janecka, Mary, Jenkins, Paula, Juškaitis, Rimvydas, Juste, Javier, Kays, Roland, Kilpatrick, C. William, Kingston, Tigga, Koprowski, John L., Kryštufek, Boris, Lavery, Tyrone, Lee, Thomas E., Leite, Yuri L. R., Novaes, Roberto Leonan M., Lim, Burton K., Lissovsky, Andrey, López‐Antoñanzas, Raquel, López‐Baucells, Adrià, MacLeod, Colin D., Maisels, Fiona G., Mares, Michael A., Marsh, Helene, Mattioli, Stefano, Meijaard, Erik, Monadjem, Ara, Morton, F. Blake, Musser, Grace, Nadler, Tilo, Norris, Ryan W., Ojeda, Agustina, Ordóñez‐Garza, Nicté, Pardiñas, Ulyses F. J., Patterson, Bruce D., Pavan, Ana, Pennay, Michael, Pereira, Calebe, Prado, Joyce, Queiroz, Helder L., Richardson, Matthew, Riley, Erin P., Rossiter, Stephen J., Rubenstein, Daniel I., Ruelas, Dennisse, Salazar‐Bravo, Jorge, Schai‐Braun, Stéphanie, Schank, Cody J., Schwitzer, Christoph, Sheeran, Lori K., Shekelle, Myron, Shenbrot, Georgy, Soisook, Pipat, Solari, Sergio, Southgate, Richard, Superina, Mariella, Taber, Andrew B., Talebi, Maurício, Taylor, Peter, Vu Dinh, Thong, Ting, Nelson, Tirira, Diego G., Tsang, Susan, Turvey, Samuel T., Valdez, Raul, Van Cakenberghe, Victor, Veron, Geraldine, Wallis, Janette, Wells, Rod, Whittaker, Danielle, Williamson, Elizabeth A., Wittemyer, George, Woinarski, John, Zinner, Dietmar, Upham, Nathan S., Jetz, Walter
Publicado 2022