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  1. 17721
    “…METHODS: The Prospective Epidemiological Research on Functioning Outcomes Related to Major depressive disorder (PERFORM) study was a longitudinal cohort study conducted in 1,159 outpatients aged 18–65 years with MDD in France, Germany, Spain, Sweden, and the UK. The patients were either initiating antidepressant monotherapy or undergoing their first switch of antidepressant. …”
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    Long-term follow-up on health-related quality of life in major depressive disorder: a 2-year European cohort study
  2. 17722
    “…SETTING: Primary care in Spain. PARTICIPANTS: A non-randomised sample of 2201 providers (general practitioners, paediatricians and nurses) was recruited during the survey. …”
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    Drivers and strategies for avoiding overuse. A cross-sectional study to explore the experience of Spanish primary care providers handling uncertainty and patients’ requests
  3. 17723
    por Pérez-Rodríguez, Almudena, Batlle, Javier, Corrales, Irene, Borràs, Nina, Rodríguez-Trillo, Ángela, Lourés, Esther, Cid, Ana Rosa, Bonanad, Santiago, Cabrera, Noelia, Moret, Andrés, Parra, Rafael, Mingot-Castellano, María Eva, Navarro, Nira, Altisent, Carmen, Pérez-Montes, Rocío, Marcellini, Shally, Moreto, Ana, Herrero, Sonia, Soto, Inmaculada, Fernández Mosteirín, Nuria, Jiménez-Yuste, Víctor, Alonso, Nieves, de Andrés Jacob, Aurora, Fontanes, Emilia, Campos, Rosa, Paloma, María José, Bermejo, Nuria, Berrueco, Rubén, Mateo, José, Arribalzaga, Karmele, Marco, Pascual, Palomo, Ángeles, Castro Quismondo, Nerea, Iñigo, Belén, Nieto, María del Mar, Vidal, Rosa, Martínez, María Paz, Aguinaco, Reyes, Tenorio, Maria, Ferreiro, María, García-Frade, Javier, Rodríguez-Huerta, Ana María, Cuesta, Jorge, Rodríguez-González, Ramón, García-Candel, Faustino, Dobón, Manuela, Aguilar, Carlos, Batlle, Fernando, Vidal, Francisco, López-Fernández, María Fernanda
    Publicado 2018
    “…The centralised study ‘Molecular and Clinical Profile of von Willebrand Disease in Spain (PCM-EVW-ES)’ has been carried out by including the phenotypic assessment and the genetic analysis by next generation sequencing (NGS) of the VWF gene (VWF). …”
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    Role of multimeric analysis of von Willebrand factor (VWF) in von Willebrand disease (VWD) diagnosis: Lessons from the PCM-EVW-ES Spanish project
  4. 17724
    “…METHODS: We prospectively studied all consecutive patients with sepsis/septic shock admitted to 72 intensive care units (ICUs) throughout Spain in two 4-month periods (before and immediately after the 3-month intervention). …”
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    Improved empirical antibiotic treatment of sepsis after an educational intervention: the ABISS-Edusepsis study
  5. 17725
    “…Among disinfection technologies available for growers, chlorine dioxide (ClO(2)) represents, after sodium hypochlorite, an alternative disinfection treatment, which is commercially applied by growers in the USA and Spain. However, in most of the cases, the suitability of this treatment has been tested against pathogenic bacteria and low attention have been given to the impact of chemical residues on the bacterial community of the vegetable tissue. …”
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    Impact of chlorine dioxide disinfection of irrigation water on the epiphytic bacterial community of baby spinach and underlying soil
  6. 17726
    “…Objective: The aim of this study was to examine the independent and combined associations of physical activity (PA) and sitting time (ST) with long-term mortality attributed to inflammatory causes other than cardiovascular disease (CVD) and cancer in a national cohort of older adults in Spain. Design: Prospective study. Setting and Participants: A cohort of 3,677 individuals (1,626 men) aged ≥60 years was followed-up during 14.3 years. …”
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    Physical Activity, Sitting Time, and Mortality From Inflammatory Diseases in Older Adults
  7. 17727
    “…A total of 1241 participants from 28 primary care centres in Spain were assessed with the following instruments: the Patient Health Questionnaire (PHQ)-9 to evaluate depression; the Generalized Anxiety Disorder Scale (GAD)-7 for anxiety; PHQ-15 for somatization; and the World Health Organization Quality of Life Instrument-Short Form (WHOQOL-Bref) to assess four broad QoL domains: physical health, psychological health, social relationships, and environment. …”
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    The association between different domains of quality of life and symptoms in primary care patients with emotional disorders
  8. 17728
    “…CONCLUSION: The three most frequent pathogenic variants in our study (34.8% of the alleles) were also the most common in other Brazilian states, Portugal, and Spain (p.V388M, p.R261Q, IVS10‐11G>A), corroborating that the Iberian Peninsula is the major source of PAH mutations in Rio de Janeiro. …”
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    Mutation analysis of the PAH gene in phenylketonuria patients from Rio de Janeiro, Southeast Brazil
  9. 17729
    “…METHODS: Data were extracted from The Health Improvement Network (UK), Health Search Database (Italy), Information System for Research in Primary Care (Spain) and Integrated Primary Care Information (Netherlands). …”
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    Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease
  10. 17730
    “…RESULTS: Forty-nine valid responses were retrieved from DCRs/SIFs in all countries where they were established at the time of the survey (Australia, Canada, Denmark, France, Germany, Luxembourg, Netherlands, Norway, Spain and Switzerland). Internationally, the operational capacities of DCRs/SIFs varied in terms of funding, location, size and staffing, but their clients all shared common features of vulnerability and marginalisation. …”
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    Drug consumption rooms (DCRs) as a setting to address hepatitis C – findings from an international online survey
  11. 17731
    “…RESULTS: Five medical oncologists from the United States, Spain, Taiwan, Korea, and Hong Kong with 14 to 30 years of experience, and 17 patients with HCC and Child-Pugh class A or B cirrhosis status completed interviews. …”
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    Integrating the patient voice with clinician reports to identify a hepatocellular carcinoma-specific subset of treatment-related symptomatic adverse events
  12. 17732
    “…SETTING: Five hospitals in Eastern Andalusia, Spain. PARTICIPANTS: 518 pairs of pregnant Spanish women. …”
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    Maternal seafood intake and the risk of small for gestational age newborns: a case–control study in Spanish women
  13. 17733
    “…METHODS: Prospective study of subjects with diabetes mellitus using electronic health records from the universal public health system in the Valencian Community, Spain 2008–2012. We included 19,140 men and women aged 30 years or older with diabetes who underwent routine health examinations in primary care. …”
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    Mortality and cardiovascular disease burden of uncontrolled diabetes in a registry-based cohort: the ESCARVAL-risk study
  14. 17734
    “…The objective of this analysis is to estimate the economic impact of these results when applied to Spain. MATERIALS AND METHODS: An Excel-based cost–consequence model with a one-year time horizon was populated with SLS COPD results, adopting the Spanish National Health System (NHS) perspective. …”
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    Cost–consequence analysis of fluticasone furoate/vilanterol 92/22 mcg for the management of COPD in the Spanish NHS
  15. 17735
    “…Surveys were conducted in Croatia, Czech Republic, France, Hungary, Israel, Italy, Spain and the UK. A total of 175 Diaporthe strains were isolated from asymptomatic and symptomatic shoots, branches and trunks. …”
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    Diaporthe diversity and pathogenicity revealed from a broad survey of grapevine diseases in Europe
  16. 17736
    “…The Dupont’s lark Chersophilus duponti is an endangered steppe-bird species whose European distribution is restricted to Spain. This scarce passerine bird could be considered an ‘umbrella species’, since its population trends may reveal the conservation status of shrub-steppes. …”
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    European population trends and current conservation status of an endangered steppe-bird species: the Dupont’s lark Chersophilus duponti
  17. 17737
    “…Countries with higher number of biosimilar prices are Spain and France. Differences in manufacturers’ prices of reference biological products in selected countries in comparison with the lowest manufacturer price are higher with 22 to 69% while the retail prices between 62 and 95%. …”
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    Comparative Price Analysis of Biological Products for Treatment of Rheumatoid Arthritis
  18. 17738
    “…In order to evaluate its discrimination capacity and utility in diversity studies, this set of markers was used in a representative number of accessions from 20 different olive growing countries and maintained at the World Olive Germplasm Collection of IFAPA Centre ‘Alameda del Obispo’ (Córdoba, Spain), one of the world’s largest olive germplasm bank. …”
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    Usefulness of a New Large Set of High Throughput EST-SNP Markers as a Tool for Olive Germplasm Collection Management
  19. 17739
    “…Trucks coming mainly from France (71.3%), Spain (14.0%), and Ireland (7.4%) went mainly to Greece (95.4%), which was also the most common nationality of the transport companies (44.6%). …”
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    Road Transport of Farm Animals: Mortality, Morbidity, Species and Country of Origin at a Southern Italian Control Post
  20. 17740
    “…BACKGROUND: The Franciscan Hospital for Children Oral Health-Related Quality of Life questionnaire (FHC-OHRQOL-Q) is an instrument designed specifically for parents and caregivers of patients with special needs that has not yet been applied in Spain. The aim of this study was to adapt it to Spanish and evaluate its reliability and validity in patients with intellectual disability (ID) treated under general anesthesia. …”
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    Validation of the Spanish version of the Franciscan Hospital for Children Oral Health-Related Quality of Life questionnaire
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