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  1. 19521
    “…In total, 2142 participants aged 16 to 22 years, with no current or past history of major depression, bipolar disorder or psychosis will be recruited across UK, Germany, Spain, and Belgium. Assessments take place at baseline (pre-randomisation), 1, 3 and 12 months post-randomisation. …”
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    Promotion of mental health in young adults via mobile phone app: study protocol of the ECoWeB (emotional competence for well-being in Young adults) cohort multiple randomised trials
  2. 19522
    “…The aim of this study was to examine the incremental burden of migraine in terms of health-related quality of life (HRQoL), impairments to work and daily activities, and healthcare resource utilization (HRU) in five European countries (France, Germany, Italy, Spain, and the UK (EU5]), by comparing migraineurs with ≥ 4 MHDs and migraineurs with 1–3 MHDs. …”
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    The Humanistic and Economic Burden of Migraine in Europe: A Cross-Sectional Survey in Five Countries
  3. 19523
    “…METHODS: We performed a multicentre retrospective cohort study in 18 tertiary hospitals in Spain from March to April 2020. Consecutive patients admitted with severe COVID-19 treated with tocilizumab were compared to patients not treated with tocilizumab, adjusting by inverse probability of the treatment weights (IPTW). …”
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    Combination of Tocilizumab and Steroids to Improve Mortality in Patients with Severe COVID-19 Infection: A Spanish, Multicenter, Cohort Study
  4. 19524
    “…METHODS: De-identified patient data were extracted from a clinical database (EuCliD®) for adult hemodialysis patients from France, Italy, Portugal, Russia and Spain who were newly prescribed SFOH for up to 1 year as part of routine clinical care. …”
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    The real-world effectiveness of sucroferric oxyhydroxide in European hemodialysis patients: a 1-year retrospective database analysis
  5. 19525
    “…METHODS: Herd-level annual data from 2007 to 2016 for 91 herds in Spain were abstracted from a sow database compiled by a veterinary consultancy firm that asked client producers to mail data files on a regular basis. …”
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    A 10-year trend in piglet pre-weaning mortality in breeding herds associated with sow herd size and number of piglets born alive
  6. 19526
    “…METHODS: A randomized controlled trial will be undertaken at primary care centers from one healthcare area in Málaga (Andalusia, Spain). Study population: patients participating in an oral anticoagulant therapy program of vitamin K antagonists. …”
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    Efficacy of a joint didactic intervention using the Junta De Andalucía School for Patients method to control prothrombin time in patients taking anticoagulants: protocol for a randomized controlled trial
  7. 19527
    “…METHODS: A retrospective observational study was conducted from the 1st of March until May 29th, 2020 in a University tertiary hospital in Barcelona, Spain. Patients with an underlying AI/IMID and symptomatic SARS-CoV-2 infection were identified in our local SARS-CoV-2 infection database. …”
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    A multidisciplinary registry of patients with autoimmune and immune-mediated diseases with symptomatic COVID-19 from a single center
  8. 19528
    “…METHODS: This was a secondary analysis of a prospective cohort study of singleton pregnancies undergoing routine first‐trimester screening conducted at Vall d'Hebron University Hospital, Barcelona, Spain, between October 2015 and September 2017. Demographic characteristics, obstetric history, maternal history and biophysical markers (mean uterine artery pulsatility index and mean arterial blood pressure (MAP)) were recorded at the first‐trimester scan (at 11 + 0 to 13 + 6 weeks' gestation). …”
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    Diagnostic accuracy of first‐trimester combined screening for early‐onset and preterm pre‐eclampsia at 8–10 compared with 11–13 weeks' gestation
  9. 19529
    “…We conducted a noninterventional, cross-sectional, web-based survey of patients with a self-reported diagnosis of HAE type 1/2 in Australia, Austria, Canada, France, Germany, Spain, Switzerland, and the United Kingdom to gain a comprehensive real-world understanding of the characteristics of HAE and its burden from the perspective of the patient. …”
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    Clinical characteristics and burden of illness in patients with hereditary angioedema: findings from a multinational patient survey
  10. 19530
    por Estella, Á., Garcia Garmendia, J.L., de la Fuente, C., Machado Casas, J.F., Yuste, M.E., Amaya Villar, R., Estecha, M.A., Yaguez Mateos, L., Cantón Bulnes, M.L., Loza, A., Mora, J., Fernández Ruiz, L., Díez del Corral Fernández, B., Rojas Amezcua, M., Rodriguez Higueras, M.I., Díaz Torres, I., Recuerda Núñez, M., Zaheri Beryanaki, M., Rivera Espinar, F., Matallana Zapata, D.F., Moreno Cano, S.G., Gimenez Beltrán, B., Muñoz, N., Sainz de Baranda Piñero, A., Bustelo Bueno, P., Moreno Barriga, E., Rios Toro, J.J., Pérez Ruiz, M., Gómez González, C., Breval Flores, A., de San José Bermejo Gómez, A., Ruiz Cabello Jimenez, M.A., Guerrero Marín, M., Ortega Ordiales, A., Tejero-Aranguren, J., Rodriguez Mejías, C., Gomez de Oña, J., de la Hoz, C., Ocaña Fernández, D., Ibañez Cuadros, S., Garnacho Montero, J.
    Publicado 2022
    “…SETTING: 26 Intensive care units (ICU) from Andalusian region in Spain. PATIENTS OR PARTICIPANTS: Consecutive critically ill patients with confirmed SARS-CoV-2 infection were included from March 8 to May 30. …”
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    Predictive factors of six-week mortality in critically ill patients with SARS-CoV-2: A multicenter prospective study
  11. 19531
    “…METHODS: This analysis draws on two data sources: (1) open-ended questions embedded in a structured online survey of 329 health care providers participating in the ATLAS-2 M trial across 13 countries; and (2) in-depth interviews with 14 providers participating in FLAIR/ ATLAS/ATLAS-2 M trials in the United States and Spain. Both assessments explored provider views and clinic dynamics related to the introduction of LA ART and were analyzed using thematic content analysis. …”
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    Multi-level considerations for optimal implementation of long-acting injectable antiretroviral therapy to treat people living with HIV: perspectives of health care providers participating in phase 3 trials
  12. 19532
    “…We describe a nested RT-PCR assay (~1500 bps) to detect multiple nucleotide changes resulting in key spike protein mutations distinctive of the major known circulating SARS-CoV-2 variants, including the three Variants of Concern (VOCs) 20I/501Y.V1 (United Kingdom), 20H/501Y.V2 (South Africa), and 20 J/501Y.V3 (Brazil), as well as the 20E.EU1 variant (Spain), the CAL.20C recently identified in California, and the mink-associated variant (GR, lineage B.1.1.298). …”
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    Rapid screening for SARS-CoV-2 variants of concern in clinical and environmental samples using nested RT-PCR assays targeting key mutations of the spike protein
  13. 19533
    “…Trial recruitment will occur in up to 40 sites in six countries (Australia, Singapore, Italy, Spain, Saudi Arabia and Lebanon). The sample size is determined by a predefined quantity of ceftolozane-tazobactam to be supplied by Merck, Sharpe and Dohme (MSD). …”
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    Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to extended-spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacterales (“MERINO-3”): study protocol for a multicentre, open-label randomised non-inferiority trial
  14. 19534
    “…BACKGROUND: To analyze incidence, use of therapeutic procedures, and in-hospital outcomes in patients with ST elevation myocardial infarction (STEMI) and non-ST elevation myocardial infarction (NSTEMI) according to the presence of type 2 diabetes (T2DM) in Spain (2016–2018) and to investigate sex differences. …”
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    Are there sex differences in the effect of type 2 diabetes in the incidence and outcomes of myocardial infarction? A matched-pair analysis using hospital discharge data
  15. 19535
    “…The majority (n = 159) of respondents were from the UK and Spain. Commonly MSUS has been used in practice for (i) diagnosing pathology, (ii) supporting rehabilitation, (iii) supporting interventions or (iv) research purposes. …”
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    Exploring the use of musculoskeletal ultrasound imaging by podiatrists: an international survey
  16. 19536
    “…METHODS: Adult patients with a PCR-confirmed diagnosis of COVID-19 requiring admission during March 2020 were consecutively selected from 7 hospitals in Madrid, Spain. Among them, we identified outpatient users of ACEIs/ARBs and divided them in two cohorts depending on treatment discontinuation/continuation at admission. …”
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    Impact of in-hospital discontinuation with angiotensin receptor blockers or converting enzyme inhibitors on mortality of COVID-19 patients: a retrospective cohort study
  17. 19537
    “…METHODS: Retrospective observational 6-month follow-up study conducted in four hospitals of Spain. A cohort of all 969 patients who were hospitalized with PCR-confirmed SARS-CoV-2 from March 1 to April 15, 2020, was included. …”
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    Sequelae, persistent symptomatology and outcomes after COVID-19 hospitalization: the ANCOHVID multicentre 6-month follow-up study
  18. 19538
    “…Included territories were the United Kingdom, France, Germany, Italy, Spain, Poland, US, Canada, Australia, Japan and China. …”
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    Burden of Clostridioides difficile infection (CDI) - a systematic review of the epidemiology of primary and recurrent CDI
  19. 19539
    por Milne, Richard, Morley, Katherine I., Almarri, Mohamed A., Anwer, Shamim, Atutornu, Jerome, Baranova, Elena E., Bevan, Paul, Cerezo, Maria, Cong, Yali, Costa, Alessia, Critchley, Christine, Fernow, Josepine, Goodhand, Peter, Hasan, Qurratulain, Hibino, Aiko, Houeland, Gry, Howard, Heidi C., Hussain, S. Zakir, Malmgren, Charlotta Ingvoldstad, Izhevskaya, Vera L., Jędrzejak, Aleksandra, Jinhong, Cao, Kimura, Megumi, Kleiderman, Erika, Leach, Brandi, Liu, Keying, Mascalzoni, Deborah, Mendes, Álvaro, Minari, Jusaku, Nicol, Dianne, Niemiec, Emilia, Patch, Christine, Pollard, Jack, Prainsack, Barbara, Rivière, Marie, Robarts, Lauren, Roberts, Jonathan, Romano, Virginia, Sheerah, Haytham A., Smith, James, Soulier, Alexandra, Steed, Claire, Stefànsdóttir, Vigdis, Tandre, Cornelia, Thorogood, Adrian, Voigt, Torsten H., Wang, Nan, West, Anne V., Yoshizawa, Go, Middleton, Anna
    Publicado 2021
    “…A clustering analysis suggests alignment between some countries in the assessment of specific measures, such as the UK and Canada, Spain and Mexico and Portugal and Brazil. China and Russia are less closely aligned with other countries in terms of the value of the measures presented. …”
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    Demonstrating trustworthiness when collecting and sharing genomic data: public views across 22 countries
  20. 19540
    “…We considered three European Region case studies, from Luxembourg, Russia and Spain to include a range of health-care systems, comparing current (suboptimal) care versus target care (structured services implemented, with provider-training and consumer-education). …”
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    Structured headache services as the solution to the ill-health burden of headache. 3. Modelling effectiveness and cost-effectiveness of implementation in Europe: findings and conclusions
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