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  1. 19741
    “…Series 1 and 2 were recruited in Barcelona, Spain and included 112 fresh frozen (FF, median age 69, 44% women) and 163 formalin-fixed paraffin-embedded (FFPE, median age 67, 39% women) samples, respectively. …”
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    Lymphocytic infiltration in stage II microsatellite stable colorectal tumors: A retrospective prognosis biomarker analysis
  2. 19742
    por Rodríguez-Leor, Oriol, Cid-Álvarez, Belén, Pérez de Prado, Armando, Rossello, Xavier, Ojeda, Soledad, Serrador, Ana, López-Palop, Ramón, Martín-Moreiras, Javier, Rumoroso, José Ramón, Cequier, Ángel, Ibáñez, Borja, Cruz-González, Ignacio, Romaguera, Rafael, Moreno, Raúl, Villa, Manuel, Ruíz-Salmerón, Rafael, Molano, Francisco, Sánchez, Carlos, Muñoz-García, Erika, Íñigo, Luís, Herrador, Juan, Gómez-Menchero, Antonio, Gómez-Menchero, Antonio, Caballero, Juan, Ojeda, Soledad, Cárdenas, Mérida, Gheorghe, Livia, Oneto, Jesús, Morales, Francisco, Valencia, Félix, Ruíz, José Ramón, Diarte, José Antonio, Avanzas, Pablo, Rondán, Juan, Peral, Vicente, Pernasetti, Lucía Vera, Hernández, Julio, Bosa, Francisco, Lorenzo, Pedro Luís Martín, Jiménez, Francisco, Hernández, José M. de la Torre, Jiménez-Mazuecos, Jesús, Lozano, Fernando, Moreu, José, Novo, Enrique, Robles, Javier, Moreiras, Javier Martín, Fernández-Vázquez, Felipe, Amat-Santos, Ignacio J., Gómez-Hospital, Joan Antoni, García-Picart, Joan, Blanco, Bruno García del, Regueiro, Ander, Carrillo-Suárez, Xavier, Tizón, Helena, Mohandes, Mohsen, Casanova, Juan, Agudelo-Montañez, Víctor, Muñoz, Juan Francisco, Franco, Juan, del Castillo, Roberto, Salinas, Pablo, Elizaga, Jaime, Sarnago, Fernando, Jiménez-Valero, Santiago, Rivero, Fernando, Oteo, Juan Francisco, Alegría-Barrero, Eduardo, Sánchez-Recalde, Ángel, Ruíz, Valeriano, Pinar, Eduardo, Pinar, Eduardo, Planas, Ana, Ledesma, Bernabé López, Berenguer, Alberto, Fernández-Cisnal, Agustín, Aguar, Pablo, Pomar, Francisco, Jerez, Miguel, Torres, Francisco, García, Ricardo, Frutos, Araceli, Nodar, Juan Miguel Ruíz, García, Koldobika, Sáez, Roberto, Torres, Alfonso, Tellería, Miren, Sadaba, Mario, Mínguez, José Ramón López, Merchán, Juan Carlos Rama, Portales, Javier, Trillo, Ramiro, Aldama, Guillermo, Fernández, Saleta, Santás, Melisa, Pérez, María Pilar Portero
    Publicado 2020
    “…METHODS: Using a multicenter, nationwide, retrospective, observational registry of consecutive patients who were managed in 75 specific STEMI care centers in Spain, we compared patient and procedural characteristics and in-hospital outcomes in 2 different cohorts with 30-day follow-up according to whether the patients had been treated before or after COVID-19. …”
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    Impacto de la COVID-19 en el tratamiento del infarto agudo de miocardio con elevación del segmento ST. La experiencia española
  3. 19743
    “…By 2050, 151 countries were forecasted to have a TFR lower than the replacement level (TFR <2·1), and 183 were forecasted to have a TFR lower than replacement by 2100. 23 countries in the reference scenario, including Japan, Thailand, and Spain, were forecasted to have population declines greater than 50% from 2017 to 2100; China's population was forecasted to decline by 48·0% (−6·1 to 68·4). …”
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    Fertility, mortality, migration, and population scenarios for 195 countries and territories from 2017 to 2100: a forecasting analysis for the Global Burden of Disease Study
  4. 19744
    “…METHODS: This study was a 48-week, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial (rituximab vs tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis; R4RA) done in 19 centres across five European countries (the UK, Belgium, Italy, Portugal, and Spain). Patients aged 18 years or older who fulfilled the 2010 American College of Rheumatology and European League Against Rheumatism classification criteria for rheumatoid arthritis and were eligible for treatment with rituximab therapy according to UK National Institute for Health and Care Excellence guidelines were eligible for inclusion in the trial. …”
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    Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
  5. 19745
    por Rodríguez-Leor, Oriol, Cid-Álvarez, Belén, Pérez de Prado, Armando, Rossello, Xavier, Ojeda, Soledad, Serrador, Ana, López-Palop, Ramón, Martín-Moreiras, Javier, Rumoroso, José Ramón, Cequier, Ángel, Ibáñez, Borja, Cruz-González, Ignacio, Romaguera, Rafael, Moreno, Raúl, Villa, Manuel, Ruíz-Salmerón, Rafael, Molano, Francisco, Sánchez, Carlos, Muñoz-García, Erika, Íñigo, Luís, Herrador, Juan, Gómez-Menchero, Antonio, Gómez-Menchero, Antonio, Caballero, Juan, Ojeda, Soledad, Cárdenas, Mérida, Gheorghe, Livia, Oneto, Jesús, Morales, Francisco, Valencia, Félix, Ruíz, José Ramón, Diarte, José Antonio, Avanzas, Pablo, Rondán, Juan, Peral, Vicente, Pernasetti, Lucía Vera, Hernández, Julio, Bosa, Francisco, Lorenzo, Pedro Luís Martín, Jiménez, Francisco, Hernández, José M de la Torre, Jiménez-Mazuecos, Jesús, Lozano, Fernando, Moreu, José, Novo, Enrique, Robles, Javier, Moreiras, Javier Martín, Fernández-Vázquez, Felipe, Amat-Santos, Ignacio J., Gómez-Hospital, Joan Antoni, García-Picart, Joan, Blanco, Bruno García del, Regueiro, Ander, Carrillo-Suárez, Xavier, Tizón, Helena, Mohandes, Mohsen, Casanova, Juan, Agudelo-Montañez, Víctor, Muñoz, Juan Francisco, Franco, Juan, del Castillo, Roberto, Salinas, Pablo, Elizaga, Jaime, Sarnago, Fernando, Jiménez-Valero, Santiago, Rivero, Fernando, Oteo, Juan Francisco, Alegría-Barrero, Eduardo, Sánchez-Recalde, Ángel, Ruíz, Valeriano, Pinar, Eduardo, Pinar, Eduardo, Planas, Ana, Ledesma, Bernabé López, Berenguer, Alberto, Fernández-Cisnal, Agustín, Aguar, Pablo, Pomar, Francisco, Jerez, Miguel, Torres, Francisco, García, Ricardo, Frutos, Araceli, Nodar, Juan Miguel Ruíz, García, Koldobika, Sáez, Roberto, Torres, Alfonso, Tellería, Miren, Sadaba, Mario, Mínguez, José Ramón López, Merchán, Juan Carlos Rama, Portales, Javier, Trillo, Ramiro, Aldama, Guillermo, Fernández, Saleta, Santás, Melisa, Pérez, María Pilar Portero
    Publicado 2020
    “…METHODS: Using a multicenter, nationwide, retrospective, observational registry of consecutive patients who were managed in 75 specific STEMI care centers in Spain, we compared patient and procedural characteristics and in-hospital outcomes in 2 different cohorts with 30-day follow-up according to whether the patients had been treated before or after COVID-19. …”
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    Impact of COVID-19 on ST-segment elevation myocardial infarction care. The Spanish experience
  6. 19746
    “…METHODS: In this international, open science, cohort analysis, we used electronic health records from Spain (Information Systems for Research in Primary Care [SIDIAP]) and the USA (Columbia University Irving Medical Center data warehouse [CUIMC] and Department of Veterans Affairs Observational Medical Outcomes Partnership [VA-OMOP]) to identify patients aged 18 years or older with at least one prescription for ACEIs and ARBs (target cohort) or calcium channel blockers (CCBs) and thiazide or thiazide-like diuretics (THZs; comparator cohort) between Nov 1, 2019, and Jan 31, 2020. …”
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    Renin–angiotensin system blockers and susceptibility to COVID-19: an international, open science, cohort analysis
  7. 19747
    por Martinez-Perez, Oscar, Prats Rodriguez, Pilar, Muner Hernandez, Marta, Encinas Pardilla, Maria Begoña, Perez Perez, Noelia, Vila Hernandez, Maria Rosa, Villalba Yarza, Ana, Nieto Velasco, Olga, Del Barrio Fernandez, Pablo Guillermo, Forcen Acebal, Laura, Orizales Lago, Carmen Maria, Martinez Varea, Alicia, Muñoz Abellana, Begoña, Suarez Arana, Maria, Fuentes Ricoy, Laura, Martinez Diago, Clara, Janeiro Freire, Maria Jesus, Alférez Alvarez-Mallo, Macarena, Casanova Pedraz, Cristina, Alomar Mateu, Onofre, Lesmes Heredia, Cristina, Wizner de Alva, Juan Carlos, Bernardo Vega, Rut, Macia Badia, Montserrat, Alvarez Colomo, Cristina, Sanchez Muñoz, Antonio, Pratcorona Alicart, Laia, Alonso Saiz, Ruben, Lopez Rodriguez, Monica, del Carmen Barbancho Lopez, Maria, Meca Casbas, Marta Ruth, Vaquerizo Ruiz, Oscar, Moran Antolin, Eva, Nuñez Valera, Maria Jose, Fernandez Fernandez, Camino, Tubau Navarra, Albert, Cano Garcia, Alejandra Maria, Baena Luque, Carmen, Soldevilla Perez, Susana, Gastaca Abasolo, Irene, Adanez Garcia, Jose, Teulon Gonzalez, Maria, Puertas Prieto, Alberto, Ostos Serna, Rosa, del Pilar Guadix Martin, Maria, Catalina Coello, Monica, Ferriols Perez, Elena, Caño Aguilar, Africa, De la Cruz Conty, Maria Luisa, Sainz Bueno, Jose Antonio
    Publicado 2021
    “…METHODS: We conducted a multicentre prospective study in pregnancy based on a universal antenatal screening program for SARS-CoV-2 infection. Throughout Spain 45 hospitals tested all women at admission on delivery ward using polymerase-chain-reaction (PCR) for COVID-19 since late March 2020. …”
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    The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis
  8. 19748
    “…CONCLUSIONS: Our results show that the discriminative performance of the C-19 index model is low for influenza cohorts and even worse among patients with COVID-19 in the United States, Spain, and South Korea. These results suggest that C-19 should not be used to aid decision-making during the COVID-19 pandemic. …”
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    Implementation of the COVID-19 Vulnerability Index Across an International Network of Health Care Data Sets: Collaborative External Validation Study
  9. 19749
    “…METHODS: A total of 21 university centers for radiation oncology from five different European countries (Germany, Switzerland, Spain, Belgium, and Austria) participated in the study which evaluated n = 347 patients with confirmed (biopsy) inoperable NSCLC in UICC stage III A/B who received radical curative-intent RCT between 2010 and 2013. …”
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    Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer—results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group
  10. 19750
    “…METHODS: We did a 60-day, randomised, double-blind, placebo-controlled, multinational phase 3 trial at 45 hospitals in Argentina, Brazil, Canada, Chile, France, Germany, Israel, Italy, Japan, Russia, and Spain. We included adults (≥18 years) admitted to hospital with laboratory-confirmed SARS-CoV-2 infection and pneumonia, who required oxygen supplementation or intensive care. …”
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    Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial
  11. 19751
    por Tardif, Jean-Claude, Bouabdallaoui, Nadia, L'Allier, Philippe L, Gaudet, Daniel, Shah, Binita, Pillinger, Michael H, Lopez-Sendon, Jose, da Luz, Protasio, Verret, Lucie, Audet, Sylvia, Dupuis, Jocelyn, Denault, André, Pelletier, Martin, Tessier, Philippe A, Samson, Sarah, Fortin, Denis, Tardif, Jean-Daniel, Busseuil, David, Goulet, Elisabeth, Lacoste, Chantal, Dubois, Anick, Joshi, Avni Y, Waters, David D, Hsue, Priscilla, Lepor, Norman E, Lesage, Frédéric, Sainturet, Nicolas, Roy-Clavel, Eve, Bassevitch, Zohar, Orfanos, Andreas, Stamatescu, Gabriela, Grégoire, Jean C, Busque, Lambert, Lavallée, Christian, Hétu, Pierre-Olivier, Paquette, Jean-Sébastien, Deftereos, Spyridon G, Levesque, Sylvie, Cossette, Mariève, Nozza, Anna, Chabot-Blanchet, Malorie, Dubé, Marie-Pierre, Guertin, Marie-Claude, Boivin, Guy
    Publicado 2021
    “…The study was done in Brazil, Canada, Greece, South Africa, Spain, and the USA, and was led by the Montreal Heart Institute. …”
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    Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial
  12. 19752
    “…FINDINGS: Between April 24 and 30, 2021, 676 individuals were enrolled and randomly assigned to either the intervention group (n=450) or control group (n=226) at five university hospitals in Spain (mean age 44 years [SD 9]; 382 [57%] women and 294 [43%] men). 663 (98%) participants (n=441 intervention, n=222 control) completed the study up to day 14. …”
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    Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial
  13. 19753
    “…The event took place in the Sala Apolo, Barcelona, Spain. Adults aged 18–59 years with a negative result in an Ag-RDT from a nasopharyngeal swab collected immediately before entering the event were randomised 1:1 (block randomisation stratified by age and gender) to either attend the indoor event for 5 hours or go home. …”
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    Same-day SARS-CoV-2 antigen test screening in an indoor mass-gathering live music event: a randomised controlled trial
  14. 19754
    “…We summarize the outcomes from a preliminary cohort of patients from Brazil, Greece, Italy, Spain, Switzerland, the UK and the US. Actively managed patients with an established diagnosis of CL from March to October 2020 were included according to the Institutional Protection of Human Subjects guidelines at the respective centers. …”
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    International Cutaneous Lymphomas Pandemic Section (ICLYPS) analysis of CTCL outcomes during COVID-19
  15. 19755
    “…Results were confirmed in the Alzheimer’s and Families (ALFA+) study (Barcelona, Spain), which included individuals with preclinical AD, and the BioCogBank Paris Lariboisière cohort (Paris, France), which included individuals with symptomatic AD. …”
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    Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum
  16. 19756
    “…METHODS: Following a pilot study with seven Bolivian migrants to Spain, we tested 71 serum samples from chronic patients (mean age 12.6 years) inhabiting the Argentine Chaco region. …”
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    Assessing antibody decline after chemotherapy of early chronic Chagas disease patients
  17. 19757
    “…Therefore, we aimed to assess the impact of immunotherapy, chemotherapy, and chemoimmunotherapy on the immunogenicity and safety of the mRNA-1273 (Moderna Biotech, Madrid, Spain) COVID-19 vaccine as part of the Vaccination Against COVID in Cancer (VOICE) trial. …”
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    mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial
  18. 19758
    “…Most isolates were from the US (43.3%), Spain (24.1%), France (20.5%), and Costa Rica (7.1%). …”
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    1320. In Vitro Activity of Lefamulin against Staphylococcus aureus Isolated from the Lower Respiratory Tract of Children with Cystic Fibrosis
  19. 19759
    por Santos García, Diego, de Deus Fonticoba, Teresa, Cores, Carlos, Muñoz, Guillermo, Paz González, Jose M., Martínez Miró, Cristina, Suárez, Ester, Jesús, Silvia, Aguilar, Miquel, Pastor, Pau, Planellas, Lluis, Cosgaya, Marina, García Caldentey, Juan, Caballol, Nuria, Legarda, Inés, Hernández Vara, Jorge, Cabo, Iria, López Manzanares, Luis, González Aramburu, Isabel, Ávila Rivera, María A., Catalán, Maria J., Nogueira, Víctor, Puente, Víctor, Ruíz de Arcos, María, Borrué, Carmen, Solano Vila, Berta, Álvarez Sauco, María, Vela, Lydia, Escalante, Sonia, Cubo, Esther, Carrillo Padilla, Francisco, Martínez Castrillo, Juan C., Sánchez Alonso, Pilar, Alonso Losada, Maria G., López Ariztegui, Nuria, Gastón, Itziar, Clavero, Pedro, Kulisevsky, Jaime, Blázquez Estrada, Marta, Seijo, Manuel, Rúiz Martínez, Javier, Valero, Caridad, Kurtis, Mónica, de Fábregues, Oriol, González Ardura, Jessica, Ordás, Carlos, López Díaz, Luis M., McAfee, Darrian, Martinez-Martin, Pablo, Mir, Pablo
    Publicado 2021
    “…PD patients recruited from 35 centers of Spain from the COPPADIS cohort from January 2016, to November 2017, were followed up during 2 years. …”
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    Predictors of clinically significant quality of life impairment in Parkinson’s disease
  20. 19760
    “…Materials & methods: Nine patients with previous exposure to SARS-CoV-2 who underwent AHSTC (Table 1) and 8 healthy donors who recovered from mild COVID-19 were recruited from Hospital Ramón y Cajal and Primary Healthcare Center Pedro Laín Entralgo (Madrid, Spain), respectively. Specific direct cellular cytotoxicity (DCC) of PBMCs from these patients against Vero E6 cells infected with pseudotyped SARS-CoV-2 was determined. …”
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    Characterization of the Humoral and Cellular Immune Response Against the Natural Infection By Sars-Cov-2 in Oncohematological Patients with Post-COVID19 Autologous Transplantation
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