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241por Mark, Christoph, Grundy, Thomas J, Strissel, Pamela L, Böhringer, David, Grummel, Nadine, Gerum, Richard, Steinwachs, Julian, Hack, Carolin C, Beckmann, Matthias W, Eckstein, Markus, Strick, Reiner, O'Neill, Geraldine M, Fabry, BenEnlace del recurso
Publicado 2020
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242“…In particular, treatment with the growth factor TGFβ1 directs differentiation of the spheroidal liver progenitor cells toward a biliary phenotype, a behavior which is further enhanced in the presence of hydrogel microparticles. …”
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243por Edwards, Steven J., Carannante, Valentina, Kuhnigk, Kyra, Ring, Henrik, Tararuk, Tatsiana, Hallböök, Finn, Blom, Hans, Önfelt, Björn, Brismar, Hjalmar“…We provide a practical method for the study of spheroids, organoids and tumor-infiltrating immune cells at high resolution without the loss of spatial organization. …”
Publicado 2020
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244“…The effects of excitation frequencies on the cell accumulation time, diameter of the formed cell spheroids, and subsequently, the growth and viability of cell spheroids in the culture medium over time were studied. …”
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246por Pratiwi, Feby Wijaya, Peng, Chien-Chung, Wu, Si-Han, Kuo, Chiung Wen, Mou, Chung-Yuan, Tung, Yi-Chung, Chen, Peilin“…Here, we report a multihierarchical assessment of the accumulation and penetration of fluorescence-labeled MSNs with nine different physicochemical properties in tumor spheroids using two-photon microscopy. Our results indicated that individual physicochemical parameters separately could not define the MSNs’ ability to accumulate in a deeper tumor region; their features are entangled. …”
Publicado 2020
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247por Shen, Honglin, Cai, Shuxiang, Wu, Chuanxiang, Yang, Wenguang, Yu, Haibo, Liu, Lianqing“…Three-dimensional multicellular spheroids (MCSs) have received extensive attention in the field of biomedicine due to their ability to simulate the structure and function of tissues in vivo more accurately than traditional in vitro two-dimensional models and to simulate cell–cell and cell extracellular matrix (ECM) interactions. …”
Publicado 2021
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248“…Numerical simulations revealed that prolate spheroids move faster than spherical particles, and oblate spheroids move slower than spherical particles. …”
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249por Park, Yoonseok, Franz, Colin K., Ryu, Hanjun, Luan, Haiwen, Cotton, Kristen Y., Kim, Jong Uk, Chung, Ted S., Zhao, Shiwei, Vazquez-Guardado, Abraham, Yang, Da Som, Li, Kan, Avila, Raudel, Phillips, Jack K., Quezada, Maria J., Jang, Hokyung, Kwak, Sung Soo, Won, Sang Min, Kwon, Kyeongha, Jeong, Hyoyoung, Bandodkar, Amay J., Han, Mengdi, Zhao, Hangbo, Osher, Gabrielle R., Wang, Heling, Lee, KunHyuck, Zhang, Yihui, Huang, Yonggang, Finan, John D., Rogers, John A.“…Here, we introduce classes of microfabricated 3D frameworks as compliant, multifunctional neural interfaces to spheroids and to assembloids. Electrical, optical, chemical, and thermal interfaces to cortical spheroids demonstrate some of the capabilities. …”
Publicado 2021
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250“…This paper proposes to model the fruit shape as a 3D spheroid. The spheroid size and pose in each view is estimated from the silhouettes of all views. …”
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251por Jeger-Madiot, Nathan, Arakelian, Lousineh, Setterblad, Niclas, Bruneval, Patrick, Hoyos, Mauricio, Larghero, Jérôme, Aider, Jean-Luc“…In recent years, 3D cell culture models such as spheroid or organoid technologies have known important developments. …”
Publicado 2021
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252“…For this purpose we used a 3D spheroid culture system optimal for neural stem cells propagation. …”
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253“…We conclude that experimental evolution in monolayers tends to be more reproducible than in spheroids or explants, and better preserves oncoselectivity. …”
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254“…Spheroids replicate tissue physiological activities. …”
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255por Bergdorf, Kensey N., Phifer, Courtney J., Bechard, Matthew E., Lee, Mason A., McDonald, Oliver G., Lee, Ethan, Weiss, Vivian L.Enlace del recurso
Publicado 2021
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256“…In this study, we engineer three-dimensional “spark cells” spheroids, composed of ChR2-expressing human embryonic kidney cells (from 100 to 100,000 cells per spheroid), and characterize their morphology as function of cell density and time. …”
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257por Dakhel, Soran, Davies, Wayne I. L., Joseph, Justin V., Tomar, Tushar, Remeseiro, Silvia, Gunhaga, Lena“…CONCLUSION: The establishment of a broad ranging and highly effective method to generate FOSs from different organs was successful in terms of the formation of healthy, proliferating 3D organ spheroids that exhibited organ-like characteristics. …”
Publicado 2021
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258“…This protocol describes the necessary preparations and procedures to photo-activate Yes-associated protein (YAP) with optoYAP in cancer cell spheroids in 3D collagen matrices. We detail steps for immunofluorescent staining of the resulting YAP-activated HeLa spheroids. …”
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259por Kosheleva, Nastasia V., Efremov, Yuri M., Shavkuta, Boris S., Zurina, Irina M., Zhang, Deying, Zhang, Yuanyuan, Minaev, Nikita V., Gorkun, Anastasiya A., Wei, Shicheng, Shpichka, Anastasia I., Saburina, Irina N., Timashev, Peter S.Enlace del recurso
Publicado 2021
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260por Langthasa, Jimpi, Sarkar, Purba, Narayanan, Shruthi, Bhagat, Rahul, Vadaparty, Annapurna, Bhat, Ramray“…Ovarian cancer metastasizes into peritoneum through dissemination of transformed epithelia as multicellular spheroids. Harvested from the malignant ascites of patients, spheroids exhibit startling features of organization typical to homeostatic glandular tissues: lumen surrounded by smoothly contoured and adhered epithelia. …”
Publicado 2021
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