“…Introduction of PDL spheroids into the stroma of porcine corneas resulted in extensive migration of cells inside the host stroma after 14‐day organ culture. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro tumor targeting was explored in monolayer (2D) and multilayer tumor spheroid (3D) HepG2 cancer cell models (GLUT1(+)). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Post thaw, cryo-CSSCs were characterized for stemness using phenotypic and genotypic markers along with colony-forming efficiency and three-dimensional spheroid formation. Multilineage differentiation was observed by differentiation into osteocytes, adipocytes, neural cells, and keratocytes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also found that embigin promotes prostate cancer growth, spheroid- and colony-forming ability, and survival upon chemotherapy independently of S100A4. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Invasion by cancer-CAF spheroids into the fibrin matrix was more clearly observed in the 3D cell sheet. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Short-term exposure of 3D-spheroids to Fe(3)O(4)NP induced cytotoxicity at 10 µg/mL in astrocytes and 25 µg/mL neurons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CNTD2 overexpression in CRC cell lines increases their proliferation capacity and migration, as well as spheroid formation capacity and anchorage-independent growth. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IEC monolayers form 3D spheroids in matrigel culture and monolayers on transwell inserts making them useful for functional analyses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In stage III, neoplastic cells expressing nestin, CD133 and nestin/CD133 reside in spheroid-like aggregates (SAs) and in the neoangiogenic border. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To clarify the role of actin cytoskeleton, spheroid Sw.71 cells were treated mycalolide B (inhibitor of actin polymerization) in a 3D culture. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Kaplan Meier (KM)-plotter analysis was performed to analyze the correlation between STARD13 expression and overall survival of HCC patients. Cell spheroid formation and ALDH1 activity analysis were carried out to detect the effects of STARD13 on the stemness of HCC cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cell samples and tissue punches can adhere to the surface of the cell plate or utilize spheroid plates, respectively. However, the spherical, three-dimensional shape of D. melanogaster brains prevents the tissue from adhering to the plate. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IL‐17A signalling also altered sulphated glycosaminoglycan deposition and spheroid colony formation, while treatment with small‐molecule inhibitors of IL‐17A attenuated this response. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cardiomyocytes derived from induced pluripotent stem cells (iCells), endothelial cells, and fibroblasts were combined to make the spheroids. Subsequently, tubular cardiac constructs were fabricated by Bio-3D printer placing the spheroids on a needle array. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Before the induction of 3D organization, single clonal SGSCs were preconditioned to aggregate to form 3D spheroids in different matrices, such as Matrigel, floating dish, and microwells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Quantitative real-time PCR (qRT-PCR) and western blot were used to detect the expression of stemness markers in MCF-7-P and MCF-7 cells. Additionally, cell spheroid formation, Transwell migration, ALDH1 activity, and flow cytometry assays were performed to detect stemness and migration ability of MCF-7-P cells, and the effects of everolimus on MCF-7-P cells stemness and migration ability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Next, TMZ PK‐PD in a solid tumor was demonstrated to highly depend on its spatial configuration as spread cancer cells or fragmented tumors presented higher TMZ‐induced damage as compared to compact tumor spheroid. Simulations highlighted that smaller tumors were less acidic than bigger ones allowing for faster TMZ activation and their closer distance to blood capillaries allowed for better drug penetration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A high throughput histology (microTMA) platform was applied for testing drugs against tumors in a novel 3D heterotypic glioblastoma brain sphere (gBS) model consisting of glioblastoma tumor cells, iPSC-derived neurons, glial cells and astrocytes grown in a spheroid. The differential responses of gBS tumors and normal neuronal cells to sustained treatments with anti-cancer drugs temozolomide (TMZ) and doxorubicin (DOX) were investigated. gBS were exposed to TMZ or DOX over a 7-day period. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also used in the present study TS543 human proneural glioma cells that were grown as spheroid culture. TS543 neurospheres exhibited dramatic sensitivity to CBD-mediated killing that was additionally increased in combination with γ-irradiation and KU60019. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The expression of CSC marker genes, including CD133 and EpCAM, was significantly downregulated in the spheroids of CD44‐deficient cells compared with those in the spheroids of HuH7 cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso