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Mostrando 301 - 320 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.11s Limitar resultados
  1. 301
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    Comparative pO2 measurements in cell spheroids cultured with different techniques.
  2. 302
    por Twentyman, P. R.
    Publicado 1980
    “…Multicellular tumour spheroids of the EMT6 mouse tumour line have been grown in a static (i.e. non-spinner) culture system to a mean spheroid diameter of 250 mum. …”
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    Response to chemotherapy of EMT6 spheroids as measured by growth delay and cell survival.
  3. 303
    por Twentyman, P. R.
    Publicado 1983
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    Exclusion of host cells during spheroid formation from disaggregated solid tumours.
  4. 304
    “…In the present study organotypic multicellular spheroids (OMS) were used to study the effects of chemotherapeutic agents on malignant gliomas. …”
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    Daunorubicin and doxorubicin but not BCNU have deleterious effects on organotypic multicellular spheroids of gliomas.
  5. 305
    “…We have investigated the cytotoxic efficacy of beta, alpha and Auger electron-emitting radioconjugates in treating neuroblastoma cells grown in monolayer or spheroid culture. Using a no-carrier-added synthesis route, we produced 123I-, 125I-, 131I- and 211At-labelled benzylguanidines and compared their in vitro toxicity to the neuroblastoma cell line SK-N-BE(2c) grown in monolayer and spheroid culture. …”
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    Toxicity to neuroblastoma cells and spheroids of benzylguanidine conjugated to radionuclides with short-range emissions.
  6. 306
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    Electrophysiology of Supramedullary Neurons in Spheroides maculatus : II. Properties of the electrically excitable membrane
  7. 307
    “…We then studied spheroids grown from actual mesothelioma. ABT-737 was active in spheroids grown from those tumors (5/7, ∼70%) with elevated levels of Bim. …”
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    The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance
  8. 308
    “…Moreover, we suggest that carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) isoform balance is associated with hollow spheroid formation. METHODS: Immunohistochemical analyses with CEACAM1 and M30 as an apoptosis marker were performed to examine the importance of hollow spheroid CEACAM1 expression and central cell apoptosis in hollow spheroid formation. …”
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    Hollow spheroids beyond the invasive margin indicate the malignant potential of colorectal cancer
  9. 309
    “…RESULTS: At 5 Gy irradiation UGBM1 and U-87MG spheroids showed growth inhibition whereas the MO59J spheroid was relatively radioresistant. …”
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    Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
  10. 310
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    Penetration of Endothelial Cell Coated Multicellular Tumor Spheroids by Iron Oxide Nanoparticles
  11. 311
    “…BACKGROUND: MultiCellular Tumor Spheroid (MCTS) mimics the organization of a tumor and is considered as an invaluable model to study cancer cell biology and to evaluate new antiproliferative drugs. …”
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    Multicellular tumor spheroid models to explore cell cycle checkpoints in 3D
  12. 312
    “…Hereditary diffuse leukoencephalopathy with spheroids (HDLS) in humans is a rare autosomal dominant disease characterized by giant neuroaxonal swellings (spheroids) within the CNS white matter. …”
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    CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function
  13. 313
    “…We also discuss possible mechanisms that could be involved in regulating APAP-induced autophagy/mitophagy and the formation of mitochondrial spheroids.…”
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    Zonated induction of autophagy and mitochondrial spheroids limits acetaminophen-induced necrosis in the liver()
  14. 314
    “…We show that small interfering RNA (siRNA)-targeting PKCι decreased the size of all spheroids tested and partially reversed the aberrant polarity phenotype in H-Ras and ErbB2 spheroids only. …”
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    Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids
  15. 315
    “…After the coculture experiment, the brain tissue or the 3D cell spheroids can be collected and used for further molecular analyses (e.g. qRT-PCR, IHC, or immunoblot) as well as for investigations by confocal microscopy. …”
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    Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells
  16. 316
    por Razian, Golsa, Yu, Yang, Ungrin, Mark
    Publicado 2013
    “…Tumor spheroids are increasingly recognized as an important in vitro model for the behavior of tumor cells in three dimensions. …”
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    Production of Large Numbers of Size-controlled Tumor Spheroids Using Microwell Plates
  17. 317
    “…However, spheroids have been little used for the study of various oligonucleotide delivery formulations. …”
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    Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions
  18. 318
    “…In this study, we demonstrated that LGR5 was highly expressed in CCSCs-enriched HT29 spheroid cells. Downregulation of LGR5 with small interfering RNA (siRNA) decreased the expression of stem the cell markers CD133 and CD44 in HT29 spheroid cells. …”
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    LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells
  19. 319
    por Bilandzic, Maree, Stenvers, Kaye L.
    Publicado 2014
    “…To mimic the peritoneal microenvironment encountered by tumor cells in vivo, a spheroid-mesothelial co-culture model was established in which preformed spheroids are plated on top of a human mesothelial cell monolayer, formed over an extracellular matrix barrier. …”
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    Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
  20. 320
    “…Our results indicate that tumor spheroids are enriched for CD44(hi)CD24(lo)ALDH1(hi) cells, a phenotype that is predominantly known to be a marker for breast cancer stem cells. …”
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    TRAIL-Mediated Apoptosis in Breast Cancer Cells Cultured as 3D Spheroids
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