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Mostrando 321 - 340 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.15s Limitar resultados
  1. 321
    “…Our results indicate that spheroid culture increases their multi-potency and changes the epigenetic status of pluripotent genes in hMSCs.…”
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    Epigenetic changes of mesenchymal stem cells in three-dimensional (3D) spheroids
  2. 322
    “…In this study, we assessed whether the osteoregenerative potential of MSC spheroids is greater than that of monolayer MSCs. RESULTS: MSC spheroids were generated from rat MSCs (rMSCs) using low-binding plates. …”
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    Mesenchymal stem cell spheroids exhibit enhanced in-vitro and in-vivo osteoregenerative potential
  3. 323
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    When is a vesicle not just a vesicle: mitochondrial spheroids and mitochondrial autophagosomes
  4. 324
    “…Nucleostemin (NS), a nucleolar-localized protein, modulates cell cycle progression, stemness, and three-dimensional tumor spheroid formation. The signaling pathways that regulate NS levels in tumors remain undefined. …”
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    FAK activity protects nucleostemin in facilitating breast cancer spheroid and tumor growth
  5. 325
    “…Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. …”
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    Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing
  6. 326
    “…Here we describe a novel and reproducible method for high content analysis of invading cells using multicellular tumour spheroid assays in a high grade glioma model. Live cell imaging of spheroids generated from glioma cell lines, U87 and U251, gave insight into migration dynamics and cell morphology in response to anti-migratory drugs. …”
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    High-content analysis of tumour cell invasion in three-dimensional spheroid assays
  7. 327
    “…Under the usual approximation of treating a biological particle as a spheroidal droplet, we consider the analysis of its size and shape with the high frequency photoacoustics and develop a numerical method which can simulate its characteristic photoacoustic waves. …”
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    Simulating photoacoustic waves produced by individual biological particles with spheroidal wave functions
  8. 328
    “…Metastatic epithelial ovarian cancer (EOC) cells can form multicellular spheroids while in suspension and disperse directly throughout the peritoneum to seed secondary lesions. …”
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    Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids
  9. 329
    “…Here we present a spontaneously-forming in vitro cancer spheroid model, referred to as spheroids(MARY-X), that precisely reflects the pathophysiological features commonly found in tumor tissues and the lymphovascular embolus. …”
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    Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening
  10. 330
    “…Using cisplatin sensitive and resistant cell lines assembled into 3D spheroids we profiled gene expression and identified candidate mechanisms and biological pathways associated with cisplatin resistance. …”
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    Cisplatin Resistant Spheroids Model Clinically Relevant Survival Mechanisms in Ovarian Tumors
  11. 331
    “…Here, the effect of the anticancer drug cisplatin, also known as cis-diamminedichloroplatinum (II) or CDDP, on adenosine triphosphate (ATP) generation was investigated using 3D spheroid-forming cells and real-time monitoring for 7 days. …”
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    Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells
  12. 332
    “…Multicellular tumor spheroids are powerful in vitro models to perform preclinical chemosensitivity assays. …”
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    Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity
  13. 333
    por Wan, Xiao, Li, Zhaohui, Ye, Hua, Cui, Zhanfeng
    Publicado 2016
    “…RESULTS: The perfused cancer spheroid model showed higher cell viability and increased diameter of spheroids over a relatively long culture period (17 days). …”
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    Three-dimensional perfused tumour spheroid model for anti-cancer drug screening
  14. 334
    “…We recently developed a 3-dimensional spheroid model of quiescent breast cancer cells in bone marrow for mechanistic and drug testing studies. …”
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    Imaging Sensitivity of Quiescent Cancer Cells to Metabolic Perturbations in Bone Marrow Spheroids
  15. 335
    “…However, after activation mTHPC entrapped into 50 nm particles destroyed cancer spheroids as efficiently as the free drug. Cell death and gene expression studies provide evidence that encapsulation may lead to different cell killing modes in PDT. …”
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    Photoinduced effects of m-tetrahydroxyphenylchlorin loaded lipid nanoemulsions on multicellular tumor spheroids
  16. 336
    “…Here, we evaluated two 3D spheroid models, one from primary human hepatocytes (PHH) and one from HepaRG cells, for the detection of compounds with cholestatic liability. …”
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    Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability
  17. 337
    “…Recently, increasing numbers of cell culture experiments with 3D spheroids presented better correlating results in vivo than traditional 2D cell culture systems. 3D spheroids could offer a simple and highly reproducible model that would exhibit many characteristics of natural tissue, such as the production of extracellular matrix. …”
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    Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time
  18. 338
    “…Three-dimensional multicellular aggregates such as spheroids provide reliable in vitro substitutes for tissues. …”
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    Multiscale image analysis reveals structural heterogeneity of the cell microenvironment in homotypic spheroids
  19. 339
    “…Multicellular tumor spheroid (MCTS) culture models were developed to mimic these features. …”
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    Induction of hypoxia and necrosis in multicellular tumor spheroids is associated with resistance to chemotherapy treatment
  20. 340
    “…In that context, 3D in vitro tumor models such as cancer cell spheroids are becoming increasingly popular. We obtained spheroids of human breast adenocarcinoma SKBR-3 overexpressing the HER2 cancer marker. …”
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    Spheroids of HER2-Positive Breast Adenocarcinoma for Studying Anticancer Immunotoxins In Vitro
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