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21por Song, Liqing, Yuan, Xuegang, Jones, Zachary, Griffin, Kyle, Zhou, Yi, Ma, Teng, Li, Yan“…The objective of this study is to investigate the impacts of neural spheroids and vascular spheroids interactions on the regional brain-like tissue patterning in cortical spheroids derived from human iPSCs. …”
Publicado 2019
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22“…BACKGROUND: Our group has developed a novel method for spontaneous spheroid formation using a specific low-adherence culture plate with around 90° water contact angle. …”
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23por Gendre, Dylan A.J., Ameti, Edis, Karenovics, Wolfram, Perriraz-Mayer, Nadja, Triponez, Frédéric, Serre-Beinier, Véronique“…Monitoring the growth kinetic and intracellular ATP of spheroids allowed the identification of early changes in spheroid viability. …”
Publicado 2021
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24por Kutle, Ivana, Polten, Robert, Hachenberg, Jens, Klapdor, Rüdiger, Morgan, Michael, Schambach, Axel“…The review emphasizes the potential of 3D tumor models, such as spheroids from cervical cancer cell lines and patient-derived organoids, to evaluate novel therapies, particularly immunotherapies that target tumor cells and modulate the tumor microenvironment. …”
Publicado 2023
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25por Minaeva, Ekaterina D., Antoshin, Artem A., Kosheleva, Nastasia V., Koteneva, Polina I., Gonchukov, Sergey A., Tsypina, Svetlana I., Yusupov, Vladimir I., Timashev, Peter S., Minaev, Nikita V.“…Laser printing with cell spheroids can become a promising approach in tissue engineering and regenerative medicine. …”
Publicado 2023
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26por Pierangeli, Davide, Perini, Giordano, Palmieri, Valentina, Grecco, Ivana, Friggeri, Ginevra, De Spirito, Marco, Papi, Massimiliano, DelRe, Eugenio, Conti, Claudio“…We here discover that tumor-cell spheroids manifest optical rogue waves when illuminated by randomly modulated laser beams. …”
Publicado 2023
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27por Agrawal, Ayushi, Lasli, Soufian, Javanmardi, Yousef, Coursier, Diane, Micalet, Auxtine, Watson, Sara, Shahreza, Somayeh, Serwinski, Bianca, Djordjevic, Boris, Szita, Nicolas, Cheema, Umber, Bertazzo, Sergio, Calvo, Fernando, Moeendarbary, Emad“…This study reports the integration of stromal cells in spheroid contractility assays that impacts the ECM remodelling and invasion abilities of cancer spheroids. …”
Publicado 2023
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28por Casadidio, Cristina, Hartman, Jet E. M., Mesquita, Bárbara S., Haegebaert, Ragna, Remaut, Katrien, Neumann, Myriam, Hak, Jaimie, Censi, Roberta, Di Martino, Piera, Hennink, Wim E., Vermonden, Tina“…SiRNA and pDNA polyplexes were tracked in vitro into tumor spheroids, resembling in vivo avascular ovarian tumor nodules. …”
Publicado 2023
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29“…BACKGROUND: Malignant ascites often develops in advanced stages of ovarian carcinoma, consisting of single and aggregated tumor cells, or spheroids. Spheroids have commonly been used as tumor models to study drug efficacy, and have shown resistance to some chemotherapies and radiation. …”
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30por Durand, R. E.“…The cytotoxicity of two antineoplastic drugs, cisplatin and CCNU, was evaluated in Chinese hamster V79 multicell spheroids using the drugs as single agents or combinations. …”
Publicado 1990
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31“…We have used fluorescence-activated cell sorting to evaluate chemopotentiation by misonidazole as a function of cell position in V79 spheroids and KHT tumours. CCNU toxicity was enhanced in all cell subpopulations of both tumours and spheroids, with greater consistency than might be predicted on the basis of the known variations in oxygen tension. …”
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32“…BACKGROUND: Our objective was to discover in silico axioms that are plausible representations of the operating principles realized during characteristic growth of EMT6/Ro mouse mammary tumor spheroids in culture. To reach that objective we engineered and iteratively falsified an agent-based analogue of EMT6 spheroid growth. …”
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34“…RESULTS: We successfully isolated primary tumor spheroids from the pancreatic tumor samples and were able to maintain the spheroids in culture for up to two weeks. …”
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35por Birey, Fikri, Andersen, Jimena, Makinson, Christopher D., Islam, Saiful, Wei, Wu, Huber, Nina, Fan, H. Christina, Cordes Metzler, Kimberly R., Panagiotakos, Georgia, Thom, Nicholas, O’Rourke, Nancy A., Steinmetz, Lars M., Bernstein, Jonathan A., Hallmayer, Joachim, Huguenard, John R., Pașca, Sergiu P.“…These subdomain-specific forebrain spheroids can be assembled to recapitulate the saltatory migration of interneurons similar to migration in fetal forebrain. …”
Publicado 2017
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36“…The present reviews highlight the recent advances and the development of microfluidics based methods for the generation of cell spheroids. The paper emphasizes on the application of microfluidic technology for tissue engineering including the formation of multicellular spheroids (MCS). …”
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37por Madhavan, Mayur, Nevin, Zachary S., Shick, H. Elizabeth, Garrison, Eric, Clarkson-Paredes, Cheryl, Karl, Molly, Clayton, Benjamin L.L., Factor, Daniel C., Allan, Kevin C., Barbar, Lilianne, Jain, Tanya, Douvaras, Panagiotis, Fossati, Valentina, Miller, Robert H., Tesar, Paul J.“…Promyelinating drugs enhance the rate and extent of oligodendrocyte generation and myelination, while oligocortical spheroids generated from patients with a genetic myelin disorder recapitulate human disease phenotypes. …”
Publicado 2018
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38“…The structure of multi-domain micromagnetic states in hcp cobalt nanoparticles of spheroidal shape has been studied using numerical simulation in the range of diameters 20–200 nm. …”
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39por Duan, Yufeng, Li, Xuebing, Zhang, Sicheng, Wang, Shikai, Wang, Tao, Chen, Hong, Yang, Yan, Jia, Sixun, Chen, Guoqing, Tian, Weidong“…Methods: Here, we constructed a 3D culture method to expand functional HERS cells into spheroids, and investigated characteristics and application of dental tissue regeneration of these spheroids. …”
Publicado 2020
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40por Sadati, Monirosadat, Martinez-Gonzalez, Jose A., Zhou, Ye, Qazvini, Nader Taheri, Kurtenbach, Khia, Li, Xiao, Bukusoglu, Emre, Zhang, Rui, Abbott, Nicholas L., Hernandez-Ortiz, Juan Pablo, de Pablo, Juan J.Enlace del recurso
Publicado 2020
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