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  1. 3981
    “…For the numerical simulations the density fluctuations were approximated as a set of spheroids distributed inside the Si layers as a 3D para­crystal (a lattice of spheroids with short-range ordering but lacking any long-range order). …”
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    Grazing-incidence small-angle X-ray scattering study of correlated lateral density fluctuations in W/Si multilayers
  2. 3982
    “…Here, we developed a novel differentiation method of human induced pluripotent stem cells (hiPS cells) to generate three-dimensional (3D) neural spheroids that contain oligodendrocytes as well as neurons and astrocytes, called human oligodendrocyte spheroids (hOLS). …”
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    Differentiation and Maturation of Oligodendrocytes in Human Three-Dimensional Neural Cultures
  3. 3983
    “…The results revealed that the microbially synthesized PbS nanocrystals assume a cubic structure, and are often aggregated as spheroids of about 105 nm in size. These spheroids are composed of numerous nanoparticles with diameter 5–10 nm. …”
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    Bacterial synthesis of PbS nanocrystallites in one-step with l-cysteine serving as both sulfur source and capping ligand
  4. 3984
    “…CDX2(+) cells localized in the out layer of the spheroids, while OCT4(+) cells in the inner of the structures. …”
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    Combination of epigenetic erasing and mechanical cues to generate human epiBlastoids from adult dermal fibroblasts
  5. 3985
    “…RESULTS: We showed that HNSCC cells from different tumors formed spheroids that differed in size and density in regard to EMT-associated protein expression and culturing time. …”
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    The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
  6. 3986
    “…Transplant of ASC/ECFC 3D spheroids in vivo demonstrated pro-angiogenic capacity with improved therapeutic potential.…”
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    3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing
  7. 3987
    “…In contrast, HER2BC forms compact spheroids prompted by autonomous extracellular matrix components and segregating stromal cells to their periphery. …”
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    Distinct tumor architectures for metastatic colonization of the brain
  8. 3988
    “…DNA-PKi exhibited an inhibitory effect on the proliferation of MYCN-driven neuroblastoma spheroids, whereas variable sensitivity was observed in those cell lines. …”
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    DNA Ligase 4 Contributes to Cell Proliferation against DNA-PK Inhibition in MYCN-Amplified Neuroblastoma IMR32 Cells
  9. 3989
    “…In order to overcome the common hindrances encountered while using this technology, a fully 3D-printed device was developed that sustains patient-derived multicellular spheroids long enough to conduct multiple drug screening tests. …”
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    A fully 3D-printed versatile tumor-on-a-chip allows multi-drug screening and correlation with clinical outcomes for personalized medicine
  10. 3990
    por Mehl, James B.
    Publicado 2007
    “…Specific examples are worked out for the radial (ℓ = 0) and triplet (ℓ = 1) modes, for prolate and oblate spheroids, and for triaxial ellipsoids. The exact eigenvalues for the spheroids, and eigenvalue determined with finite-element calculations, are shown to agree with perturbation theory through terms of order ε(2). …”
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    Acoustic Eigenvalues of a Quasispherical Resonator: Second Order Shape Perturbation Theory for Arbitrary Modes
  11. 3991
    “…Finally, using intravital microscopy, we observe that tumor spheroids display filopodia in vivo, supporting a potential role for these protrusions during tumorigenesis.…”
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    FiloQuant reveals increased filopodia density during breast cancer progression
  12. 3992
    “…As prototypic applications breast and colorectal cancer (CRC) spheroids were analyzed by pheno-seq. We identified characteristic gene expression signatures of epithelial-to-mesenchymal transition that are associated with invasive growth behavior of clonal breast cancer spheroids. …”
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    Pheno-seq – linking visual features and gene expression in 3D cell culture systems
  13. 3993
    por Selvadurai, A. P. S., Suvorov, A. P.
    Publicado 2020
    “…The pore density and the aspect ratio of the spheroidal pores influence the porosity of the geomaterials. …”
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    The influence of the pore shape on the bulk modulus and the Biot coefficient of fluid-saturated porous rocks
  14. 3994
    “…The multicellular constructs supported the formation of tumor spheroids with extensive F-actin networks surrounding the spheroids, enabling cell-cell communication, and comparative cell-matrix interactions and encapsulation response to those observed in Matrigel. …”
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    Peptide-protein coassembling matrices as a biomimetic 3D model of ovarian cancer
  15. 3995
    “…Antibiotic treatment of infected spheroids, monitored through time-dependent Doppler shifts, can distinguish drug-resistant relative to non-resistant strains. …”
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    Doppler imaging detects bacterial infection of living tissue
  16. 3996
    “…Colony-stimulating factor-1 receptor-microglial encephalopathy is a rare rapidly progressive dementia resulting from colony-stimulating factor-1 receptor (CSF1R) mutations, also named pigmentary orthochromatic leukodystrophy (POLD), hereditary diffuse leukoencephalopathy with spheroids (HDLS), adult-onset leukoencephalopathy with axonal spheroids, and pigmented glia (ALSP) and CSF1R-related leukoencephalopathy. …”
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    Recent Advances in Basic Research for CSF1R-Microglial Encephalopathy
  17. 3997
    “…Prolate spheroidal harmonics are applied to a Turing reaction-diffusion system, providing a chemically based framework for cortical folding. …”
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    Chemically Based Mathematical Model for Development of Cerebral Cortical Folding Patterns
  18. 3998
    “…We also confirm the suitability of using 3D spheroids of Human Embryonic Kidney (HEK-293) cells for upgrading the 2D cell-based assay. …”
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    A Genetically Encoded Bioluminescence Intracellular Nanosensor for Androgen Receptor Activation Monitoring in 3D Cell Models
  19. 3999
    “…In recent years, various 3D models of cancer cells have been developed, notably in the form of spheroids/organoids, using scaffold or cancer-on-chip devices. …”
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    Current Advances in 3D Bioprinting for Cancer Modeling and Personalized Medicine
  20. 4000
    “…METHODS: Our system enabled preparation of a highly concentrated EV-containing medium for efficient EV isolation and purification with higher yield and efficacy. RESULTS: MSC spheroids in T-a3D system (T-a3D spheroids) showed high expression of CD9 and TGF-β3, which was dependent on TGF-β signaling. …”
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    Advanced 3D dynamic culture system with transforming growth factor-β3 enhances production of potent extracellular vesicles with modified protein cargoes via upregulation of TGF-β signaling
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