“…Assuming Newtonian fluid flow at low Reynolds number in a spheroidal cell, we first compute the flow field exactly, thereby bypassing the need for numerical computations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study explores the changes in the CRC cytokine profile depending on the culture conditions and the presence of fibroblasts and macrophages as cellular components of the tumor microenvironment in 2D and in 3D formed spheroids. Upon analysis of 45 different cytokines, chemokines and growth factors, 20 CRC cell lines were categorized into high and low secretors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: We have developed a new family of growth models that predict the volumetric growth behavior of multicellular tumor spheroids with a high degree of accuracy. We strongly believe that the family of hyperbolastic models can be a valuable predictive tool in many areas of biomedical and epidemiological research such as cancer or stem cell growth and infectious disease outbreaks.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this process, the hollow, spheroidal Volvox embryo turns inside-out through a small opening called the phialopore to bring flagella from its inner to its outer surface. …”
Enlace del recurso
Enlace del recurso

“…In addition, aggregations of pre-synaptic markers are apparent in white matter tracts and the thalamus and are likely to be formed within axonal spheroids. Our data provide a new perspective, revealing a number of events that occur prior to and alongside neuron loss and highlighting that these occur in a pathway dependent manner.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nitroxoline also markedly decreased tumor cell invasion monitored in real time and reduced the invasive growth of multicellular tumor spheroids, used as a 3D in vitro model of tumor invasion. …”
Enlace del recurso
Enlace del recurso

“…Thus, the stellate cells of the monolayer became spheroids and were isolated. Our results indicate that rHelja is a promising tool for the development of diagnostic or therapeutic methods for neuroblastoma cells, the most common solid tumors in childhood.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Gold deposited on anatase spheroidal TiO(2) at photo-deposition wavelength of 410 nm for 5 min resulted in the highest CO oxidation activity of 0.0617 mmol CO/s.g(Au) (89.5% conversion) due to the comparatively highest catalyst surface area (114.4 m(2)/g), smallest gold particle size (2.8 nm), highest gold loading (7.2%), and highest Au(0) content (68 mg/g catalyst). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mammalian hearts contain a small fraction of progenitor cells which, in culture, migrate out of the cardiac explants, known as explant-derived cell (EDCs) and contribute to spheroids known as cardiospheres (Csphs). Following further culture and cell passaging, Csphs give rise to cardiosphere-derived cells (CDCs). …”
Enlace del recurso
Enlace del recurso

“…Drug combinations altered the redox stage of promastigotes, rapidly dissipated mitochondrial membrane potential and induced concatenation of mitochondrial network promoting spheroidal morphology. These results evidenced a potent and specific antileishmanial effect of the peptaibols/miltefosine combinations, achieved with significantly lower concentrations of the compounds compared to monotherapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compacted graphite iron provides the best possible compromise between optimum mechanical properties, compared to flake graphite iron, and optimum thermal conductivity, compared to spheroidal graphite iron. The vermicular-shaped graphite particles, however, act as stress concentrators, and, as a result of delamination from the metal matrix, they are responsible for crack initiation during the thermomechanical fatigue cycles occurring through engine startup and shutdown cycles. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In conclusion, fascaplysin shows high activity against lung cancer cell lines and spheroids of SCLC CTCs which are linked to the dismal prognosis of this tumor type. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We developed a functional in vitro assay to dissect the complex processes directing angiogenesis during wound healing, whereby vascular cell spheroids were induced to sprout in the presence of classically (M1) or alternatively (M2) activated macrophages. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Metastasis of SCLC is linked to an extremely high number of circulating tumor cells (CTCs), which form chemoresistant spheroids, termed tumorospheres. Intravasation and extravasation during tumor spread requires the activity of a number of proteases to disintegrate the stroma and vascular tissue. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We show that CD271 is expressed at low levels in primary cSCC cells and the number of CD271+ cells correlates with cell cohesion in SCC spheroids. In normal epidermis, CD271 is expressed in proliferative progenitor cells and DLX3 in terminally differentiated keratinocytes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The Py8119 cell line was cloned from a spontaneous mammary tumor in a Tg(MMTV:LTR-PyVmT) C57Bl/6 mouse and these cells form 3-dimensional (3D) spheroids under conditions of low adhesion. Co-cultured BMM infiltrate the Py8119 mammospheres and embedding of the infiltrated mammospheres in Matrigel leads to subsequent invasion of both cell types into the surrounding matrix. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Several types of monogenic, hereditary cerebral SVD have been identified: cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL), cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), cathepsin A-related arteriopathy with strokes and leukoencephalopathy (CARASAL), hereditary diffuse leukoencephalopathy with spheroids (HDLS), COL4A1/2-related disorders, and Fabry disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro examinations including cytotoxicity, cellular uptake and penetration in multicellular tumor spheroids and in vivo observations including IFP and tumor solid stress measurements and antitumor activity were performed. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the MDA-MB 231 cell line, it allows three-dimensional growth of structures known as spheroids, while in HCC1569 it achieves a cell organization similar to that observed in vivo. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, the presence of Sn yielded the most uniform, spheroidal and finest particles after the longest milling time.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso