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Mostrando 561 - 580 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.42s Limitar resultados
  1. 561
    “…BACKGROUND: Ovarian cancer cells aggregate during or after exfoliation from the primary tumor to form threedimensional spheroids. Spheroid formation provides a survival advantage during peritoneal dissemination in nutrient and oxygen-depleted conditions which is accompanied by a suppressed metabolic phenotype and fragmented mitochondria. …”
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    Mitochondrial plasticity supports proliferative outgrowth and invasion of ovarian cancer spheroids during adhesion
  2. 562
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    The Effect of Carnosine on UVA-Induced Changes in Intracellular Signaling of Human Skin Fibroblast Spheroids
  3. 563
    “…Thus, preclinical assays that reflect patients’ responses to treatments are of utmost importance in clinical oncology and in developing new drugs. 3D tumour models such as spheroids and ex vivo tumour explants are appropriate preclinical models. …”
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    Pixelated Microfluidics for Drug Screening on Tumour Spheroids and Ex Vivo Microdissected Tumour Explants
  4. 564
    “…In this study, we generated MN spheroids and developed a workflow to analyze them. …”
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    An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
  5. 565
    “…We demonstrate that HPV-positive spheroids keep their higher intrinsic radiosensitivity when compared to HPV-negative spheroids. …”
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    Use of 3D Spheroid Models for the Assessment of RT Response in Head and Neck Cancer
  6. 566
    “…The presence of PrP(Sc) in spheroids was also confirmed by immunocytochemistry. …”
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    Susceptibility of Ovine Bone Marrow-Derived Mesenchymal Stem Cell Spheroids to Scrapie Prion Infection
  7. 567
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    An AARS1 variant identified to cause adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia
  8. 568
    “…Differences in EwS spheroid growth and viability were measured by microscopy. …”
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    Combinatorial drug screening on 3D Ewing sarcoma spheroids using droplet-based microfluidics
  9. 569
    “…SIMPLE SUMMARY: Acoustic holograms were investigated as a method of delivering simultaneously controlled ultrasound hyperthermia to multiple tumor spheroids. Findings show that holographic lenses designed to deliver a uniform thermal dose rather than a uniform acoustic field can tune the natural focus of a transducer, allowing the exposure to ultrasound-mediated hyperthermia of several tumor spheroids simultaneously, and improving experimental throughput for future studies. …”
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    Holographic Focused Ultrasound Hyperthermia System for Uniform Simultaneous Thermal Exposure of Multiple Tumor Spheroids
  10. 570
    “…The objective of the present work was to develop a three-dimensional culture model to evaluate, in a short period of time, cartilage tissue engineering protocols. The spheroids were compared with the gold standard pellet culture. …”
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    Spheroid Culture System, a Promising Method for Chondrogenic Differentiation of Dental Mesenchymal Stem Cells
  11. 571
    “…This study examines the impacts of copper and boron in parts per million (ppm) on the microstructure and mechanical properties of spheroidal graphite cast iron (SCI). Boron’s inclusion increases the ferrite content whereas copper augments the stability of pearlite. …”
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    The Effect of Boron (B) and Copper (Cu) on the Microstructure and Graphite Morphology of Spheroidal Graphite Cast Iron
  12. 572
    “…By exposing such spheroids to various factors and compounds, it is possible to study changes in FAP expression, which are easily detected by confocal microscopy. …”
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    Spheroids of FAP-Positive Cell Lines as a Model for Screening Drugs That Affect FAP Expression
  13. 573
    “…Multicellular spheroids comprised of malignant cells, endothelial cells, and mesenchymal stem cells served as an in vitro model of human solid tumors to investigate the potentiation of DNA-damaging drugs by pharmacologic modulation of DNA repair pathways. …”
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    Multicellular Complex Tumor Spheroid Response to DNA Repair Inhibitors in Combination with DNA-damaging Drugs
  14. 574
    “…In this study, we utilised A375 human melanoma spheroids to screen the phototoxic effect of zinc phthalocyanine tetrasulfonate (ZnPcS(4)) conjugated to gold nanoparticles (AuNP). …”
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    The Efficacy of Zinc Phthalocyanine Nanoconjugate on Melanoma Cells Grown as Three-Dimensional Multicellular Tumour Spheroids
  15. 575
    “…Interestingly, unlike tumor spheroid maintenance, RB restoration could functionally revert metastatic tumor spheroids to a nonmetastatic cell state. …”
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    Metastatic Competency and Tumor Spheroid Formation Are Independent Cell States Governed by RB in Lung Adenocarcinoma
  16. 576
    “…We found that chemical activation of Piezo1 by its agonist, Yoda1, prevents melanoma spheroid formation; thus, Piezo1 could be a potential target for selective modulation aimed at the prevention of melanoma development.…”
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    Piezo1 Activation Prevents Spheroid Formation by Malignant Melanoma SK-MEL-2 Cells
  17. 577
    “…Functionally, the spheroid becomes competent morphogenetic units (CMU) that promote regeneration of tissue patterns. …”
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    Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
  18. 578
    “…The resulting mineralized spheroids promote an osteogenic gene expression profile through the influence of the spheroids’ biophysical environment and inorganic signaling and require less calcium or phosphate to achieve mineralization compared to a monolayer culture. …”
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    An in vitro model system based on calcium- and phosphate ion-induced hMSC spheroid mineralization
  19. 579
    “…However, the non expression of P-gp by cells forming multicellular spheroids has only a minor impact in the resistance to chemotherapeutic agents.…”
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    Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids
  20. 580
    “…A system was designed to allow imaging of control and drug treated multicellular spheroids with a high frequency backscatter ultrasound microscope. …”
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    Use of a high frequency ultrasound microscope to image the action of 2-nitroimidazoles in multicellular spheroids.
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