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Mostrando 41 - 60 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.19s Limitar resultados
  1. 41
    “…SIMPLE SUMMARY: Cell cultures can be carried out in three dimensions (3D). Organoids and spheroids are different 3D cell culture models that can be cultured with different techniques. …”
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  2. 42
    “…Most strikingly, GemIP‐mediated GEM delivery leads to the overt disintegration of targeted GBM tumor spheroids. Electrically‐driven chemotherapy, here exemplified, has the potential to radically improve the efficacy of GBM adjuvant chemotherapy by enabling exquisitely‐targeted and controllable delivery of drugs irrespective of whether these can cross the BBB.…”
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    “…In mathematical biology, solid tumor spheroids are often studied as preliminary in vitro models of avascular tumors. …”
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  5. 45
    “…This method could be an attractive way to control their properties in the future, based on the similarity of spheroids with in vivo tumor models.…”
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  6. 46
    “…To improve the therapeutic effect of cell spheroids even further, various biomaterials (e.g., nano- or microparticles, fibers, and hydrogels) have been developed for spheroid engineering. …”
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  7. 47
    “…In a model toxicology challenge, the thawed spheroids matched the performance of fresh spheroids. …”
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    “…Three-dimensional cell culture has many advantages over monolayer cultures, and spheroids have been hailed as the best current representation of small avascular tumours in vitro. …”
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  10. 50
    “…This study presents a high-throughput image analysis software application – SpheroidSizer, which measures the major and minor axial length of the imaged 3D tumor spheroids automatically and accurately; calculates the volume of each individual 3D tumor spheroid; then outputs the results in two different forms in spreadsheets for easy manipulations in the subsequent data analysis. …”
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  14. 54
    por Kim, WonJin, Kim, GeunHyung
    Publicado 2022
    “…Here, we introduce a new cell‐printing process, fabricating cell‐spheroids and cell‐loaded constructs together without preparation of cell‐spheroids in advance. …”
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  15. 55
    “…Cancer cell spheroids have been shown to mimic in vivo tumour microenvironment and are therefore suitable for in vitro drug screening. …”
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  16. 56
    “…Our study explores the role of collagen type I in cancer development and spread using engineered tumor models like multicellular spheroids grown in collagen-based hydrogels to simulate early tumor formation. …”
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  17. 57
    “…Both carbohydrate ligands used are proposed to bind to asialoglycoprotein receptors (ASGPRs) in hepatic cells, thus inducing spheroid formation when seeding hepatic HepG2 cells on both supramolecular hydrogels. …”
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  18. 58
    “…Multicellular spheroids are useful models for drug testing or studying tumor biology, but their production requires specialized approaches. …”
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  19. 59
    “…Heterotypic 3D tumor spheroids, composed of multiple cell types, have become more popular than homotypic spheroids, which consist of a single cell type, as a superior model for mimicking in vivo tumor heterogeneity and physiology. …”
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  20. 60
    “…Biomaterials offer numerous opportunities to preserve spheroid function and guide spheroid behavior by tailoring the local microenvironment.…”
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