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Mostrando 581 - 600 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.14s Limitar resultados
  1. 581
    por Tannock, I. F., Steele, D., Roberts, J.
    Publicado 1986
    “…Lower concentration of glutamine suppressed the rate of spheroid growth, and spheroids did not grow in the absence of glutamine. …”
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    Influence of reduced concentration of L-glutamine on growth and viability of cells in monolayer, in spheroids, and in experimental tumours.
  2. 582
    “…Tumour cells from 7 patients with ovarian carcinoma and from 22 different human tumour xenografts representing a wide range of histological sub-types have been examined for multicellular spheroid forming ability. Spheroid formation was limited to cells derived from xenografts. …”
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    In vitro cytotoxic drug sensitivity testing of human tumour xenografts grown as multicellular tumour spheroids.
  3. 583
    “…In this study, we have investigated whether hyperthermia increased the cytotoxicity of an 211At-labelled monoclonal antibody (MAb) in tumour spheroids with a radius (approximately 100 microm) greater than the range of 211At alpha-particles. …”
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    Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia.
  4. 584
    “…We recently showed that severe hypoxia was not universally present adjacent to necrosis in human glioma xenografts and spheroids established from the M059K, M006, M006X, M006XLo and M010b cell lines. …”
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    Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours
  5. 585
    “…Moreover, after transplantation of spheroids into the mouse liver, the spheroid-derived cells integrated into recipient. …”
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    Differentiation and Selection of Hepatocyte Precursors in Suspension Spheroid Culture of Transgenic Murine Embryonic Stem Cells
  6. 586
    “…When grown in 3D cultures as spheroids, mesothelioma cells acquire a multicellular resistance to apoptosis that resembles that of solid tumors. …”
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    Vorinostat Eliminates Multicellular Resistance of Mesothelioma 3D Spheroids via Restoration of Noxa Expression
  7. 587
    “…Here we described protein transfection studies of the commercially available reagents, Pro-DeliverIN, Xfect, and TuboFect, using Huh-7 multicellular tumor spheroid (MCTS) as a three-dimensional in vitro tumor model. …”
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    Protein Transfection Study Using Multicellular Tumor Spheroids of Human Hepatoma Huh-7 Cells
  8. 588
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    A clinicopathological and genetic study of sporadic diffuse leukoencephalopathy with spheroids: a report of two cases
  9. 589
    “…The multi cellular tumor spheroid (MCTS) model has been used for decades with proven superiority over monolayer cell culture models at recapitulating in vivo tumor growth. …”
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    Live Multicellular Tumor Spheroid Models For High-Content Imaging and Screening In Cancer Drug Discovery
  10. 590
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    Multicellular tumor spheroids in microcapsules as a novel 3D in vitro model in tumor biology
  11. 591
    “…The endothelial cell spheroid assay provides a suitable in vitro model to study (lymph) angiogenesis and test pro- and anti-(lymph) angiogenic factors or drugs. …”
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    Cell Invasion in the Spheroid Sprouting Assay: A Spatial Organisation Analysis Adaptable to Cell Behaviour
  12. 592
    “…RESULTS: Morphological analysis showed that spheroids were of about 250 μm in size and varied in structure, while the spheroid cells differed in shape and size and were tightly packed together by desmosomes and tight junctions. …”
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    Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture
  13. 593
    “…PURPOSE: Corneal stromal cells transform to precursor cells in spheroid culture. We determined whether keratocytes derived from spheroid culture of murine corneal stromal cells resemble tissue resident keratocytes. …”
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    Keratocytes Derived from Spheroid Culture of Corneal Stromal Cells Resemble Tissue Resident Keratocytes
  14. 594
    “…Cancer cells form three dimensional (3D) multicellular aggregates (or spheroids) under non-adherent culture conditions. In ovarian cancer (OC), spheroids serve as a vehicle for cancer cell dissemination in the peritoneal cavity, protecting cells from environmental stress-induced anoikis. …”
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    Beta-Catenin Regulated ALDH1A1 is a Target in Ovarian Cancer Spheroids
  15. 595
    “…The strength and direction of the influence of SWCNTs on the tumor cell population was assessed by cell counting and measurement of the volume of multicellular tumor spheroids. Effect of SWCNTs on the formation of multicellular spheroids was compared with the results obtained by culturing tumor cells with ultra dispersed diamonds (UDDs). …”
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    Effect of single-walled carbon nanotubes on tumor cells viability and formation of multicellular tumor spheroids
  16. 596
    “…Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. …”
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    Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids
  17. 597
    “…Here we investigate potential toxicities of equivalent doses of free and actively loaded liposomal TPT (LTPT) and compare them to a fractionated low dose regimen of free TPT in tumor-endothelial spheroids (TES) with/without radiation exposure for a prolonged period of 10 days. …”
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    An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids
  18. 598
    “…Expression of genes related to not only drug, but also glucose and lipid metabolism were significantly enhanced in 3D cultured HepaRG spheroids. Furthermore, mRNA levels of CYP (cytochrome P450) enzymes following exposure to corresponding inducers increased under the 3D condition. …”
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    3D spheroid cultures improve the metabolic gene expression profiles of HepaRG cells
  19. 599
    “…In the present study, solid three-dimensional (3D) multicellular tumor spheroids (MCTS) of the colorectal adenocarcinoma cell line HT-29 were generated and tested for their potential to study prodrug-converting enzyme therapies using bacterial vectors in vitro. …”
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    Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy
  20. 600
    “…One example of simple 3D culture is spheroids; ball shaped structures typically used as liver and tumour models. …”
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    Direct Measurements of Oxygen Gradients in Spheroid Culture System Using Electron Parametric Resonance Oximetry
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