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Mostrando 681 - 700 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 1.78s Limitar resultados
  1. 681
    “…In this study, as a proof of concept, we conducted tumour spheroid dissemination assay on engineered surfaces with micrograting patterns. …”
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    Microenvironmental topographic cues influence migration dynamics of nasopharyngeal carcinoma cells from tumour spheroids
  2. 682
    “…In particular, the cavities in the system facilitate hADSC spheroid formation, increasing therapeutic growth factor expression compared with 2D cultured cells. …”
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    Development of a stem cell spheroid‐laden patch with high retention at skin wound site
  3. 683
    “…The in vivo-relevant phenotype of 3D liver spheroids allows for long-term studies of, e.g., novel mechanisms of chronic drug-induced liver toxicity. …”
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    Hepatocyte Thorns, A Novel Drug-Induced Stress Response in Human and Mouse Liver Spheroids
  4. 684
    “…The microstructural and mechanical stability of the 3D spheroidal droplets was assessed and was found to be ideal for a cardiac scaffold. …”
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    3D Bioprinted Spheroidal Droplets for Engineering the Heterocellular Coupling between Cardiomyocytes and Cardiac Fibroblasts
  5. 685
    “…Importantly, the newly formed hybrid spheroid preserved the 3D architecture for the next 24 h. …”
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    Formation of Lymphoma Hybrid Spheroids and Drug Testing in Real Time with the Use of Fluorescence Optical Tweezers
  6. 686
    “…IC(50) curves were unsuitable for large-sized LNCaP spheroids. More evaluation indexes (such as max inhibition) and experiments (such as spheroids formation) should be explored and performed to evaluate the susceptibility systematically.…”
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    IC(50): an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation
  7. 687
    “…Increasing evidence suggests enhanced therapeutic efficacy of spheroids formed by three-dimensional culture of MSCs. …”
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    Mesenchymal stem cell spheroids alleviate neuropathic pain by modulating chronic inflammatory response genes
  8. 688
    “…RAP-MPs were uniformly distributed in hybrid spheroids and sustainably released RAP for ~3 weeks. …”
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    Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation
  9. 689
    “…All spheroids exhibited migratory properties and shortest distances were registered for JEG3 spheroids. …”
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    Characterization of Three-Dimensional Trophoblast Spheroids: An Alternative Model to Study the Physiological Properties of the Placental Unit
  10. 690
    “…A three-dimensional (3D) tumor spheroid model plays a critical role in mimicking tumor microenvironments in vivo. …”
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    3D Multicellular Tumor Spheroids in a Microfluidic Droplet System for Investigation of Drug Resistance
  11. 691
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    Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) Masquerading Primary Progressive Aphasia
  12. 692
    “…Oligodendrocyte spheroids (OL-spheroids) containing oligodendrocytes and neurons provide an accessible system to dissect demyelinating diseases and test therapeutic treatment. …”
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    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
  13. 693
    “…Here, we describe an ischemia/reperfusion (I/R) injury model typical of MI using mouse or human 3D in vitro cardiac spheroids (CSs). First, we demonstrated the culture and maintenance of CSs. …”
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    In vitro modeling of myocardial ischemia/reperfusion injury with murine or human 3D cardiac spheroids
  14. 694
    “…Here, we nondestructively measured the oxygen consumption rate of cell spheroids using an on-chip electrochemical device (OECD) and examined whether this rate can be used as a marker to estimate the quality of cell spheroids. …”
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    Quality evaluation of cell spheroids for transplantation by monitoring oxygen consumption using an on-chip electrochemical device
  15. 695
    “…Multicellular tumor spheroids and tumoroids are considered ideal in vitro models that reflect the features of the tumor microenvironment. …”
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    A Novel 3D Culture Scaffold to Shorten Development Time for Multicellular Tumor Spheroids
  16. 696
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    Prunus spinosa Extract Sensitized HCT116 Spheroids to 5-Fluorouracil Toxicity, Inhibiting Autophagy
  17. 697
    “…The expression of KLF4 and SOX2 was increased upon the spheroid culture of SNU-601 (KLF4/Nanog-high) and SNU-638 (KLF4/Nanog-low). …”
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    Modulation of Spheroid Forming Capacity and TRAIL Sensitivity by KLF4 and Nanog in Gastric Cancer Cells
  18. 698
    “…PaCa cells (BxPC-3) were co-cultured with PSC and PSC-P cells in a 3D environment to form tumor spheroids mimicking the tumor microenvironment. The extracellular collagen production of spheroids was evaluated by Masson’s trichrome staining. …”
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    Targeting Periostin Expression Makes Pancreatic Cancer Spheroids More Vulnerable to Natural Killer Cells
  19. 699
    “…In the current study, we evaluated the therapeutic effect of MSC-EVs in a cortical spheroid (CS) model of DS generated from patient-derived induced pluripotent stem cells (iPSCs). …”
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    Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome
  20. 700
    “…Our data support the use of a 3D bioprinted cardiac spheroidal droplet as a robust and high-throughput screening model for drug toxicity. …”
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    Demonstration of doxorubicin's cardiotoxicity and screening using a 3D bioprinted spheroidal droplet-based system
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