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Mostrando 901 - 920 Resultados de 6,033 Para Buscar '"Spheroid', tiempo de consulta: 0.16s Limitar resultados
  1. 901
    “…In this study, we successfully prepared and cultured cancer tissue‐originated spheroids from endometrial cancers. Characteristics of the original tumors were well retained in cancer tissue‐originated spheroids including morphology and expression of p53 or neuroendocrine markers. …”
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    Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer
  2. 902
    “…In addition, spheroid culture promoted the preservation of extracellular matrix (ECM) components, such as laminin and fibronectin, in a culture time- and spheroid size-dependent manner. …”
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    Long-Duration Three-Dimensional Spheroid Culture Promotes Angiogenic Activities of Adipose-Derived Mesenchymal Stem Cells
  3. 903
    “…Modern techniques of laser microsurgery of cell spheroids were used to develop a new simple reproducible model for studying repair and regeneration in vitro. …”
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    Laser-based technique for controlled damage of mesenchymal cell spheroids: a first step in studying reparation in vitro
  4. 904
    “…Only a subset of these circulating tumour cells (CTCs) survive, many of them presumable because of their potential to form multi-cellular clusters also named spheroids. Tumour cells within these spheroids are protected from anoikis, which allows them to metastasize to distant organs or re-seed at the primary site. …”
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    Spheroid Culture of Head and Neck Cancer Cells Reveals an Important Role of EGFR Signalling in Anchorage Independent Survival
  5. 905
    “…To our knowledge, this is the first iPSC-differentiated 3D neuro-spheroid model derived from AD patients’ blood. Our results demonstrate that our 3D human neuro-spheroid model can be a physiologically relevant and valid model for testing efficacy of AD drug.…”
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    Three Dimensional Human Neuro-Spheroid Model of Alzheimer’s Disease Based on Differentiated Induced Pluripotent Stem Cells
  6. 906
    “…Furthermore, such pressure distribution suggests a direct link between increased mechanical stress and previously observed lack of proliferation within the spheroids core.…”
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    Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression
  7. 907
    “…Multicellular three-dimensional (3D) spheroids represent an experimental model that is intermediate in its complexity between monolayer cultures and patients’ tumor. …”
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    Multicellular spheroids from normal and neoplastic thyroid tissues as a suitable model to test the effects of multikinase inhibitors
  8. 908
    “…At 1 μM, the inhibitor reduced phosphorylation of Thr308 and Ser473 residues of AKT in both adherent cells and spheroids. Low dose MK2206 delayed spheroid growth and sensitized spheroids to both irradiation and TMZ in a synergistic way (Combination index <0.35). …”
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    The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures
  9. 909
    por Yang, Chih-Cheng, Liu, Chang-Lun
    Publicado 2016
    “…In the fastener industry, most companies use a subcritical process for spheroidized annealing. Various parameters affect the spheroidized annealing quality of steel wire, such as the spheroidized annealing temperature, prolonged heating time, furnace cooling time and flow rate of nitrogen (protective atmosphere). …”
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    Improvement of the Mechanical Properties of 1022 Carbon Steel Coil by Using the Taguchi Method to Optimize Spheroidized Annealing Conditions
  10. 910
    “…Furthermore, the capability to form multicellular spheroids in vitro was compared with the intracellular distribution of NF-kappaB (NFκB) p65. …”
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    The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine
  11. 911
    “…BV2 microglial cells were stimulated with lipopolysaccharide (LPS) and treated with spheroid conditioned media (CM) or were co-cultured with whole spheroids. …”
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    Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming
  12. 912
    “…The basis for the separation of spheroids from non-spheroid forming (NSF) cells is simple gravity-sedimentation. …”
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    Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells
  13. 913
    “…Cell cultivation on an anti-adhesive substrate under static conditions was shown to lead to the formation of spheroids (3D cultures). Expression of ICAM-1 and VEGFR-2 and production of cytokines were screened in 2D and 3D cultures in the presence of TNF and VEGF. …”
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    The Effect of TNF and VEGF on the Properties of Ea.hy926 Endothelial Cells in a Model of Multi-Cellular Spheroids
  14. 914
    “…Spheroids show expression of tight junctions, adherens junctions, adherens junction-associated proteins and cell specific markers. …”
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    Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling
  15. 915
    “…AIM: To investigate the time profile of hypoxia and stem cell markers in glioblastoma spheroids of known molecular subtype. MATERIALS & METHODS: Patient-derived glioblastoma spheroids were cultured up to 7 days in either 2% or 21% oxygen. …”
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    Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia
  16. 916
    “…Thus, our results confirm the results obtained in 2-dimensional cell cultures demonstrating that electrotransfer of plasmid DNA to tumor cells in spheroids also upregulated cytosolic DNA sensors and cytokines.…”
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    Upregulation of DNA Sensors in B16.F10 Melanoma Spheroid Cells After Electrotransfer of pDNA
  17. 917
    “…The aim of this study was to develop a 3D spheroid model of gingiva to take into account epithelio-fibroblastic interactions. …”
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    Porphyromonas gingivalis bypasses epithelial barrier and modulates fibroblastic inflammatory response in an in vitro 3D spheroid model
  18. 918
    “…The accumulation inside the spheroids and toxicity of DXR were correlated with OCLN expression. …”
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    Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells
  19. 919
    “…Three-dimensional (3D) cell culture systems have been used to obtain multicellular spheroidal cell aggregates, or spheroids, from cancer cells. …”
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    Isolation of cancer cells with augmented spheroid-forming capability using a novel tool equipped with removable filter
  20. 920
    “…In this paper, we focus on the mechanical characterization of co-cultured spheroids of human umbilical vein endothelial cells (HUVECs) and mesenchymal stem cells (MSC) (HUVEC/MSC spheroids). …”
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    Temporal Transition of Mechanical Characteristics of HUVEC/MSC Spheroids Using a Microfluidic Chip with Force Sensor Probes
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