“…The surface hydrophobicity strongly influences the promotion of cell aggregate formation. In particular, for spheroid formation, highly water-repellent coatings seem to be required for the significant effects of the process. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we demonstrate a reliable and robust culture method for 3D expanding intestinal spheroids (InS(exp)) mainly comprising ISCs and progenitors, which can be derived from 3D human intestinal organoids (HIOs). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These vascular spheroids were used for fusion with iPSCs induced cerebral organoids. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We also discuss cell sources and methods for spheroid fabrication and characterization, mechanisms related to spheroid fusion, as well as enhancement of spheroid performance in the context of the IVD microenvironment.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results demonstrate that the algorithm detects known differences in sprouting parameters in endothelial spheroids treated with pro- and antiangiogenic compounds. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study aimed to evaluate the effects of FUS on human prostate and glioblastoma cancer tumour spheroids in vitro. The experimental follow-up enclosed the measurements of spheroid integrity and growth kinetics, DNA damage, and cellular metabolic activity by measuring intracellular ATP content in the spheroids. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Spheroids have become an essential tool in preclinical cancer research. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We used arrays of bioprinted renal epithelial cell spheroids for toxicity testing with cisplatin. The concentration-dependent cell death rate was determined using a lactate dehydrogenase assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The spheroids were characterized using light microscopy and histology. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The present review article observes a phenomenological approach to analyze PPI effects via concentration dependencies of self- and collective translational diffusion coefficient for several spheroidal proteins derived from the pulsed field gradient NMR (PFG NMR) and dynamic light scattering (DLS), respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Live/dead staining and size measurement of hMSC- and MG63 monolayer and spheroids were performed after administration of therapeutic plasma concentrations of modafinil, atomoxetine and guanfacine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The existing three-dimensional cell culture techniques include the hanging drop method, spinner flask method, etc., making it difficult to ensure uniform morphology of the obtained cell spheroids while performing high-throughput. Here, we report a method for amplifying cell spheroids with the advantages of quickly enlarging the culture scale and obtaining cell spheroids with uniform morphology and a survival rate of over 95%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…[Image: see text] The wall effects on the sedimentation motion of a single spheroidal particle in cylindrical tubes filled with Bingham plastic fluid are investigated with the fixed computational domain using the Computational Fluid Dynamic (CFD) model in steady-state mode. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

“…Models of our galaxy based on dynamical observations predict a spheroid component much heavier than accounted for by direct measurements of star counts and high velocity stars. …”
Enlace del recurso
Enlace del recurso

“…Furthermore, three-dimensional CD73(+) cell spheroids showed enhanced engraftment at the injured site through the enteral route, facilitated extracellular matrix remodeling, and downregulated inflammatory gene expression in fibroblasts, leading to the attenuation of colonic atrophy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moving forward, this approach will enable the detailed analysis of spheroids of any origin, one application of which is informing in silico spheroids based on their in vitro counterparts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we model a 3D spheroid tumor with subcellular resolution. The fitness of individual cells and the evolutionary behavior of the tumor are quantified and linked to cellular and environmental parameters. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Previous studies have developed vascularized tumor spheroid models to demonstrate the impact of intravascular flow on tumor progression and treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, using this applicator, we designed and validated an experimental setup which can heat 3D cell spheroids in a conical polypropylene vial, thus providing a reliable instrument for investigating hyperthermia effects at the cellular scale.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso