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  1. 261
    “…The in vivo study consisted in the analysis of the elimination and biodistribution kinetics of SPIONs after intravenous administration in Wistar rats. …”
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    Ferromagnetic resonance for the quantification of superparamagnetic iron oxide nanoparticles in biological materials
  2. 262
    “…The toxicity of superparamagnetic iron oxide nanoparticles (SPIONs) is still a vital topic of debate and the mechanisms remain unclear. …”
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    Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggers autophagic cell death in human osteosarcoma cell under a spinning magnetic field
  3. 263
    “…Superparamagnetic iron oxide nanoparticles (SPIONs) have some limitations in the physiological environment, however, a modification on their surface, such as a core–shell structure with gold (SPIONs@Au), can enhance their applicability. …”
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    Gold-Coated Superparamagnetic Iron Oxide Nanoparticles Functionalized to EGF and Ce6 Complexes for Breast Cancer Diagnoses and Therapy
  4. 264
    “…Wistar male rats were orally fed by gavage with QT and QT-SPION at 50 and 100 mg/kg daily doses for 7 days. …”
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    Using superparamagnetic iron oxide nanoparticles to enhance bioavailability of quercetin in the intact rat brain
  5. 265
    “…Bovine serum albumin (BSA) conjugated poly(acrylic acid) (PAA) coated SPIONs (BSA@PAA@SPION) were developed for encapsulation of ciprofloxacin and the nanoparticles were tagged with 4‐aminophenyl‐α‐D‐mannopyrannoside (mannoside, Man) to target E. coli fimbriae. …”
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    Fimbria targeting superparamagnetic iron oxide nanoparticles enhance the antimicrobial and antibiofilm activity of ciprofloxacin against quinolone‐resistant E. coli
  6. 266
    “…Free Cy5.5 dye and Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles (TCL-SPION) have been routinely used for in vivo optical imaging. …”
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    Distribution and accumulation of Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice
  7. 267
    “…The SPION–IL-1Ra could be a candidate for theranostic approach in neuro-oncology both for diagnosis of brain tumors and management of peritumoral edema.…”
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    Recombinant Interleukin-1 Receptor Antagonist Conjugated to Superparamagnetic Iron Oxide Nanoparticles for Theranostic Targeting of Experimental Glioblastoma()()()
  8. 268
    “…OBJECTIVE: Superparamagnetic iron oxide nanoparticles (SPIONs) have been used to label mammalian cells and to monitor their fate in vivo using magnetic resonance imaging (MRI). …”
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    Effect of Superparamagnetic Iron Oxide Nanoparticles-Labeling on Mouse Embryonic Stem Cells
  9. 269
    “…This green synthesis protocol involves the stabilization of SPIONs through coordination of different phytochemicals. …”
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    Microwave-assisted green synthesis of superparamagnetic nanoparticles using fruit peel extracts: surface engineering, T(2) relaxometry, and photodynamic treatment potential
  10. 270
    “…The SPIONs were incubated with hAMCs at concentrations of 25-800 μg/mL. …”
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    Magnetic Resonance Imaging of Human-Derived Amniotic Membrane Stem Cells Using PEGylated Superparamagnetic Iron Oxide Nanoparticles
  11. 271
    “…Hybrid materials composed of superparamagnetic iron oxide nanoparticles (SPIONs) and lipid self-assemblies possess considerable applicative potential in the biomedical field, specifically, for drug/nutrient delivery. …”
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    Lipid Cubic Mesophases Combined with Superparamagnetic Iron Oxide Nanoparticles: A Hybrid Multifunctional Platform with Tunable Magnetic Properties for Nanomedical Applications
  12. 272
    “…In this study, superparamagnetic iron oxide nanoparticles (SPIONs) were engineered with an organic coating composed of low molecular weight heparin (LMWH) and bovine serum albumin (BSA), providing heparin-based nanoparticle systems (LMWH@SPIONs). …”
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    Heparin–Superparamagnetic Iron Oxide Nanoparticles for Theranostic Applications
  13. 273
    “…Group I was treated with WJ-MSCs, group II with SPIONs/GFP-positive WJ-MSCs, and group III with SPIONs/GFP-positive WJ-MSCs exposed to an external magnetic field (EMF). …”
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    External magnetic field promotes homing of magnetized stem cells following subcutaneous injection
  14. 274
    “…In contrast, determination of the SPION amount by flow cytometry was strongly cell type-dependent and did not allow the discrimination between intracellular and membrane-bound SPIONs. …”
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    Intracellular Quantification and Localization of Label-Free Iron Oxide Nanoparticles by Holotomographic Microscopy
  15. 275
    “…Using MCF-7 and HeLa cell lines, we show that the SPIONs can provide high contrast mulicolor images of the cytoplasm from blue to red region. …”
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    Magnetofluorescent Nanoprobe for Multimodal and Multicolor Bioimaging
  16. 276
    “…In a rat model, comparable liver imaging properties, but a faster clearance was demonstrated for SPION(Dex). CONCLUSION: The results indicate that SPION(Dex) possess an exceptional safety compared to the other two formulations, making them a promising candidate for further clinical translation.…”
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    Comparative in vitro and in vivo Evaluation of Different Iron Oxide-Based Contrast Agents to Promote Clinical Translation in Compliance with Patient Safety
  17. 277
    “…In this context, we have explored for the first time the combination of type-I collagen and superparamagnetic iron oxide nanoparticles (SPIONs) to design magnetic and biocompatible electrospun scaffolds. …”
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    Incorporation of Superparamagnetic Iron Oxide Nanoparticles into Collagen Formulation for 3D Electrospun Scaffolds
  18. 278
    “…SPION-enhanced relaxivity increased as the core diameter of the nanoparticle increased, while encapsulation of SPIONs within a pSi matrix had only minor effects on T2 and no significant effect on T2* relaxation. …”
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    Characterization of Free and Porous Silicon-Encapsulated Superparamagnetic Iron Oxide Nanoparticles as Platforms for the Development of Theranostic Vaccines
  19. 279
    “…There has been a recent surge of interest in the use of superparamagnetic iron oxide nanoparticles (SPIONs) as contrast agents (CAs) for magnetic resonance imaging (MRI), due to their tunable properties and their low toxicity compared with other CAs such as gadolinium. …”
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    Liposomes Loaded with Hydrophobic Iron Oxide Nanoparticles: Suitable T(2) Contrast Agents for MRI
  20. 280
    “…The amount of HAPtS loaded onto SPIONs surface was estimated by thermogravimetric analysis (TGA) and X-ray photoelectron spectroscopy (XPS) analyses at 116 µmol·g(−1) SPIONs. …”
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    Elaboration of Trans-Resveratrol Derivative-Loaded Superparamagnetic Iron Oxide Nanoparticles for Glioma Treatment
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