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321por Thapa, Bibek, Diaz-Diestra, Daysi, Beltran-Huarac, Juan, Weiner, Brad R., Morell, Gerardo“…Anchor-free PEG-SPIONs exhibit a spin-spin relaxivity of 123 ± 6 mM(−1)s(−1), which is higher than those of PEG-SPIONs anchored with intermediate biomolecules, iron oxide nanoworms, or Feridex. …”
Publicado 2017
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322“…MATERIALS AND METHODS: The MTT assay was done at 24, 48, and 72 hours to examine the cytotoxicity of superparamagnetic iron oxide nanoparticles (SPIONs) and quercetin. We combined NGF and quercetin with different concentrations of SPIONs as novel compounds to study their effect on neuronal branching morphogenesis of PC12 cells. …”
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323por Guerra, Danieli B., Oliveira, Elisa M. N., Sonntag, Amanda R., Sbaraine, Patricia, Fay, Andre P., Morrone, Fernanda B., Papaléo, Ricardo M.“…In this work, an intercomparison of sensitization effects produced by gold (GNP) and dextran-coated iron oxide (SPION-DX) nanoparticles in M059J and U87 human glioblastoma cells was performed using 6 MV-photons. …”
Publicado 2022
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324por Dinter, Jonas, Friedrich, Ralf P., Yang, Hai, Pilarsky, Christian, Mangge, Harald, Pöttler, Marina, Janko, Christina, Alexiou, Christoph, Lyer, Stefan“…Afterwards, we formed spheroids using PaCa DD183, PANC-1 and PANC-1(SMAD4 (−/−)) cells, and analyzed the uptake and cytotoxic effect of free MTO and MTO-loaded SPIONs by microscopy and flow cytometry. MTO and SPION–MTO-induced cell death in all tumor spheroids in a dose-dependent manner. …”
Publicado 2023
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325“…In addition, combined treatment with SPION-IL4Rα+doxorubicin caused significant increases in cell death, apoptosis, and oxidative stress compared to either SPION-IL4Rα or doxorubicin alone, indicating the enhanced therapeutic efficacy of this combination. …”
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326por Heydari Sheikh Hossein, Hamid, Jabbari, Iraj, Zarepour, Atefeh, Zarrabi, Ali, Ashrafizadeh, Milad, Taherian, Afrooz, Makvandi, Pooyan“…TEM results showed that SPION@HPG was monodispersed with the average size of about 20 nm, while SPION@SiO(2)@HPG had a size of about 25 nm. …”
Publicado 2020
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327por Mireles, Laura-Karina, Sacher, Edward, Yahia, L’Hocine, Laurent, Sophie, Stanicki, Dimitri“…Much recent research on nanoparticles has occurred in the biomedical area, particularly in the area of superparamagnetic iron oxide nanoparticles (SPIONs); one such area of research is in their use as magnetically directed prodrugs. …”
Publicado 2016
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328por Chen, Yinting, Wang, Weiwei, Lian, Guoda, Qian, Chenchen, Wang, Lingyun, Zeng, Linjuan, Liao, Chengde, Liang, Biling, Huang, Bing, Huang, Kaihong, Shuai, Xintao“…Biophysical characterization of PEG-g-PEI-SPION and scFv(CD44v6)-PEG-g-PEI-SPION was carried out, including siRNA condensation capacity, cell viability, and transfection efficiency. …”
Publicado 2012
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329por Zaloga, Jan, Janko, Christina, Agarwal, Rohit, Nowak, Johannes, Müller, Robert, Boccaccini, Aldo R., Lee, Geoffrey, Odenbach, Stefan, Lyer, Stefan, Alexiou, Christoph“…Superparamagnetic iron oxide nanoparticles (SPIONs) have attracted increasing attention in many biomedical fields. …”
Publicado 2015
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330por Xie, Ruoxi, Wu, Zijun, Zeng, Fanxin, Cai, Huawei, Wang, Dan, Gu, Lei, Zhu, Hongyan, Lui, Su, Guo, Gang, Song, Bin, Li, Jinxing, Wu, Min, Gong, Qiyong“…However, compared with ANG/Cy7-SPIONs probes, (D)ANG/Cy7-SPIONs probes exhibited better enhanced MR imaging effects. …”
Publicado 2021
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331por Müller, Elena K., Gräfe, Christine, Wiekhorst, Frank, Bergemann, Christian, Weidner, Andreas, Dutz, Silvio, Clement, Joachim H.“…Superparamagnetic iron oxide nanoparticles (SPIONs) with cationic, anionic or neutral surface charge were applied. …”
Publicado 2018
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332por Ziemian, Sabina, Löwa, Norbert, Kosch, Olaf, Bajj, Daniel, Wiekhorst, Frank, Schütz, Gunnar“…We found that the amplitude of the third harmonic measured by magnetic particle spectroscopy (MPS) at 10 mT is 2.3- and 5.8-fold higher than Resovist for the MC-SPIONs and SC-SPIONs, respectively, revealing excellent MPI potential as compared to other reported MPI tracer particle preparations. …”
Publicado 2018
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333por Ebadi, Mona, Buskaran, Kalaivani, Bullo, Saifullah, Hussein, Mohd Zobir, Fakurazi, Sharida, Pastorin, Giorgia“…In this study, superparamagnetic iron oxide nanoparticles (SPIONs) were synthesized by the co-precipitation method in an alkaline medium. …”
Publicado 2020
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334por Mahajan, Ujjwal M, Teller, Steffen, Sendler, Matthias, Palankar, Raghavendra, van den Brandt, Cindy, Schwaiger, Theresa, Kühn, Jens-Peter, Ribback, Silvia, Glöckl, Gunnar, Evert, Matthias, Weitschies, Werner, Hosten, Norbert, Dombrowski, Frank, Delcea, Mihaela, Weiss, Frank-Ulrich, Lerch, Markus M, Mayerle, Julia“…RESULTS: A syngeneic orthotopic as well as an endogenous cancer model was treated biweekly with siPLK1-StAv-SPIONs and tumour growth was monitored by small animal MRI. …”
Publicado 2016
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335por Jurašin, Darija Domazet, Ćurlin, Marija, Capjak, Ivona, Crnković, Tea, Lovrić, Marija, Babič, Michal, Horák, Daniel, Vinković Vrček, Ivana, Gajović, Srećko“…The currently developed AgNPs and SPIONs encompass a myriad of sizes and surface coatings, which affect NPs properties and may improve their biocompatibility. …”
Publicado 2016
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336por Shen, Wei-Bin, Anastasiadis, Pavlos, Nguyen, Ben, Yarnell, Deborah, Yarowsky, Paul J., Frenkel, Victor, Fishman, Paul S.“…There, up to 90% of hNPCs observed contained SPIONs compared to 60% to 70% with the less powerful magnet. …”
Publicado 2017
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337por Niescioruk, Anna, Nieciecka, Dorota, Puszko, Anna K., Królikowska, Agata, Kosson, Piotr, Perret, Gerard Y., Krysinski, Pawel, Misicka, Aleksandra“…Here, we demonstrate conjugation of an antiangiogenic and antitumor peptide ATWLPPR (A7R) to SPIONs modified with sebacic acid (SPIONs-SA). Successful conjugation was confirmed by various analytical techniques (FTIR, SERS, SEM-EDS, TEM, TGA). …”
Publicado 2017
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338por Duan, Jimei, Du, Jiuju, Jin, Rongrong, Zhu, Wencheng, Liu, Li, Yang, Li, Li, Mengye, Gong, Qiyong, Song, Bin, Anderson, James M, Ai, Hua“…Dextran-coated superparamagnetic iron oxide nanoparticles (Dex-SPIONs) are excellent magnetic resonance imaging contrast agents for disease diagnosis and therapy. …”
Publicado 2019
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339“…Magnetic heating of the embedded SPIONs led to increased bilayer permeability through dehydration of the thermoresponsive PNIPAM block. …”
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340por Walker, Matthew, Will, Iain, Pratt, Andrew, Chechik, Victor, Genever, Paul, Ungar, Daniel“…Superparamagnetic iron oxide nanoparticles (SPIONs) coated with a temperature-sensitive polymer were tested for protein release. …”
Publicado 2020
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