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481por Madru, Renata, Svenmarker, Pontus, Ingvar, Christian, Ståhlberg, Freddy, Engels, Stefan-Andersson, Knutsson, Linda, Strand, Sven-Erik“…Our imaging agent is comprised of superparamagnetic iron oxide nanoparticles (SPIONs), labeled with (99m)Tc and an Alexa fluorophore (AF), together forming (99m)Tc-AF-SPIONs. …”
Publicado 2014
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482por Al-Deen, Fatin M. Nawwab, Xiang, Sue D., Ma, Charles, Wilson, Kirsty, Coppel, Ross L., Selomulya, Cordelia, Plebanski, Magdalena“…Previously, we identified optimal configurations of magnetic vectors comprising superparamagnetic iron oxide nanoparticles (SPIONs), polyethylenimine (PEI), and hyaluronic acid (HA) to deliver malaria DNA encoding Plasmodium yoelii (Py) merozoite surface protein MSP1(19) (SPIONs/PEI/DNA + HA gene complex) to dendritic cells and transfect them with high efficiency in vitro. …”
Publicado 2017
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483“…The average size of the naked SPIONs ranges from 15 to 30 nm according to the high-resolution TEM analysis. …”
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484“…The fluorescent plasmid DNA bound to the SPIONs were used as a core shell for gene delivery into the HeLa cells via magnetofection. …”
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485por Nucci, Leopoldo P, Silva, Helio R, Giampaoli, Viviana, Mamani, Javier B, Nucci, Mariana P, Gamarra, Lionel F“…This review analyzed published data on superparamagnetic iron oxide nanoparticle (SPION)-labeled stem cells used for ischemic stroke therapy. …”
Publicado 2015
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486por Ngen, Ethel J., Wang, Lee, Kato, Yoshinori, Krishnamachary, Balaji, Zhu, Wenlian, Gandhi, Nishant, Smith, Barbara, Armour, Michael, Wong, John, Gabrielson, Kathleen, Artemov, Dmitri“…Human mesenchymal stem cells were dual labelled with SPIONs and gadolinium-based chelates (GdDTPA). The viability, proliferation rate, and differentiation potential of the labelled cells were then evaluated. …”
Publicado 2015
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487por Duan, Xiaohui, Lu, Liejing, Wang, Yong, Zhang, Fang, Mao, Jiaji, Cao, Minghui, Lin, Bingling, Zhang, Xiang, Shuai, Xintao, Shen, Jun“…In this study, we used SPION-loaded cationic polymersomes to label green fluorescent protein (GFP)-expressing MSCs to determine whether MRI can accurately reflect survival, long-term fate, and potential mechanisms of MSCs in ischemic stroke therapy. …”
Publicado 2017
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488“…Nano-in-microparticles (NIMs) are a dry powder drug delivery vehicle containing superparamagnetic iron oxide nanoparticles (SPIONs) and either doxorubicin (w/w solids) or fluorescent nanospheres (w/v during formulation; as a drug surrogate) in a lactose matrix. …”
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489por Shokouhimehr, Mohammadreza, Theus, Andrea S., Kamalakar, Archana, Ning, Liqun, Cao, Cong, Tomov, Martin L., Kaiser, Jarred M., Goudy, Steven, Willett, Nick J., Jang, Ho Won, LaRock, Christopher N., Hanna, Philip, Lechtig, Aron, Yousef, Mohamed, Martins, Janaina Da Silva, Nazarian, Ara, Harris, Mitchel B., Mahmoudi, Morteza, Serpooshan, Vahid“…Here, a new generation of hyperelastic bone (HB) implants, loaded with superparamagnetic iron oxide nanoparticles (SPIONs), are 3D bioprinted and their regenerative effect on large non-healing bone fractures is studied. …”
Publicado 2021
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490por Gholami, Yaser Hadi, Yuan, Hushan, Wilks, Moses Q, Maschmeyer, Richard, Normandin, Marc D, Josephson, Lee, El Fakhri, Georges, Kuncic, Zdenka“…CONCLUSION: Our results demonstrate FH is a highly suitable SPION-based platform for chelate-free labeling of PET tracers for hybrid PET-MR. …”
Publicado 2020
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491“…Methotrexate (MTX) and superparamagnetic iron oxide nanoparticles (SPIONs) were co-encapsulated inside the SLNs to be used as therapeutic and imaging agents, respectively. …”
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492por Song, Miyeoun, Moon, Woo Kyung, Kim, Yunhee, Lim, Dongyeol, Song, In-Chan, Yoon, Byung-Woo“…RESULTS: The incorporation of SPIONs into the hNSCs did not affect the cellular proliferations and viabilities. …”
Publicado 2007
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493por Akbarzadeh, Abolfazl, Samiei, Mohammad, Joo, Sang Woo, Anzaby, Maryam, Hanifehpour, Younes, Nasrabadi, Hamid Tayefi, Davaran, Soodabeh“…These modified SPIONs were used for encapsulation of anticancer drug doxorubicin. …”
Publicado 2012
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494por Mason, Erica E., Cooley, Clarissa Z., Cauley, Stephen F., Griswold, Mark A., Conolly, Steven M., Wald, Lawrence L.“…Functional contrast is proposed based on blood SPION concentration changes due to Cerebral Blood Volume (CBV) increases during activation, a mechanism utilized in fMRI studies. …”
Publicado 2017
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495por Tabasi, Hamed, Mosavian, Mohammad Taqi Hamed, Darroudi, Majid, Khazaei, Majid, Hashemzadeh, Alireza, Sabouri, Zahra“…Superparamagnetic Iron Oxide Nanoparticles (SPIONs) have shown great potential for being utilized in Nanocarriers (NCs) applications throughout the Drug Delivery System (DDS). …”
Publicado 2022
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496por Shu, Yimeng, Ma, Ming, Pan, Xiaoxia, Shafiq, Muhammad, Yu, Huizhu, Chen, Hangrong“…Herein, a cobalt protoporphyrin IX (CoPP) aggregation-induced strategy is applied to develop a multifunctional nano-self-assembly (ASCP) by combining gold nanoparticle (AuNPs), superparamagnetic iron oxide nanoparticles (SPIONs), and CoPP through a facile solvent evaporation-driven approach. …”
Publicado 2022
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497por Choi, Wonseok, Cho, Hyeyoun, Kim, Gahee, Youn, Inchan, Key, Jaehong, Han, Sungmin“…METHODS: The rmDPPs consisted of a biodegradable polymeric matrix, rtPA, and SPIONs and were synthesized via a top-down fabrication. …”
Publicado 2022
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498por Winter, Alexander, Engels, Svenja, Reinhardt, Lena, Wasylow, Clara, Gerullis, Holger, Wawroschek, Friedhelm“…Sentinel lymph node dissection (sLND) using a magnetometer and superparamagnetic iron oxide nanoparticles (SPIONs) as a tracer was successfully applied in prostate cancer (PCa). …”
Publicado 2017
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499“…We have used a hydrothermal synthesis route that allows preparing SPION nanoparticles in the 40 nm size range, with spherical, cuboidal or rod-like shapes, by minor changes in the synthesis steps. …”
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500por de Souza, Thaís Cavalcante, Costa, Andréa Fernanda de Santana, Vinhas, Gloria Maria, Sarubbo, Leonie Asfora“…When very small, however, these particles have superparamagnetic properties and are called superparamagnetic iron oxide nanoparticles (SPIONs). Several methods are used for the production of these particles, such as coprecipitation, thermal decomposition and microemulsion. …”
Publicado 2023
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