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81por Liu, Xianping, Du, Chengjuan, Li, Haichun, Jiang, Ting, Luo, Zimiao, Pang, Zhiqing, Geng, Daoying, Zhang, Jun“…In this work, a peptide-modified, biodegradable, nontoxic, brain-tumor-targeting nanoprobe based on superparamagnetic iron oxide nanoparticles (SPIONs) (which have been commonly used as T(2)-weighted magnetic resonance (MR) contrast agents) was successfully synthesized and applied for accurate molecular MR imaging and sensitive optical imaging. …”
Publicado 2019
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82por Sillerud, Laurel O., Neuwelt, Alexander J., Staquicini, Fernanda I., Arap, Wadih, Pasqualini, Renata“…Ferumoxytol is FDA-approved as an iron replacement therapy for iron-deficiency anemia and is also a superparamagnetic iron oxide nanoparticle (SPION) resulting in negative enhancement on T(2)-weighted MR imaging. …”
Publicado 2021
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83por Puiu, Rebecca Alexandra, Balaure, Paul Cătălin, Constantinescu, Ema, Grumezescu, Alexandru Mihai, Andronescu, Ecaterina, Oprea, Ovidiu-Cristian, Vasile, Bogdan Stefan, Grumezescu, Valentina, Negut, Irina, Nica, Ionela Cristina, Stan, Miruna Silvia“…No significant modifications, neither in cell viability nor in NO level, could be observed, thereby demonstrating the excellent biocompatibility of the SPIONs thin films. Inverted phase-contrast microscopy showed no evident adverse effect on the morphology of normal osteoblasts. …”
Publicado 2021
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85por Düsenberg, Björn, Groppe, Philipp, Müssig, Stephan, Schmidt, Jochen, Bück, AndreasEnlace del recurso
Publicado 2022
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86por Park, Jeong-Eun, Kim, Woo Cheol, Kim, Sung Kyun, Ahn, Yeji, Ha, Sun Mok, Kim, Gahee, Choi, Seonmin, Yun, Wan Su, Kong, Tae Hoon, Lee, Su Hoon, Park, Dong Jun, Choi, Jin Sil, Key, Jaehong, Seo, Young Joon“…PSD-NPs and without SPIONs (PD-NPs) were prepared using a nanoprecipitation method. …”
Publicado 2022
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88por Hamzian, Nima, Hashemi, Maryam, Ghorbani, Mahdi, Bahreyni Toosi, Mohammad Hossein, Ramezani, Mohammad“…The aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates SPION and Gemcitabine in PLGA ± PEG to form multifunctional drug delivery system. …”
Publicado 2017
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89“…Furthermore, to demonstrate an application of SPIONs, we applied an external magnetic field to spheroids while incubated with FGF2-SPIONs. …”
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90por Sheu, Jiunn‐Jye, Sung, Pei‐Hsun, Wallace, Christopher Glenn, Yang, Chih‐Chao, Chen, Kuan‐Hung, Shao, Pei‐Lin, Chu, Yi‐Ching, Huang, Chi‐Ruei, Chen, Yi‐Ling, Ko, Sheung‐Fat, Lee, Mel S., Yip, Hon‐Kan“…Adult‐male SD rats (n = 40) were categorized into group 1 (SC), group 2 [SC + iPS‐MSC(SPIONs) (1.0 × 10(6)cells)/intravenous administration post‐day‐14 CKD procedure], group 3 (CKD), group 4 [CKD + iPS‐MSC(SPIONs) (0.5 × 10(6)cells)] and group 5 [CKD + iPS‐MSC(SPIONs) (1.0 × 10(6)cells)]. …”
Publicado 2020
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91por Ali, Muhammad, Kataev, Evgeny, Müller, Johannes, Park, Hyoungwon, Halik, Marcus, Hirsch, Andreas“…In this work, superparamagnetic iron oxide nanoparticles (SPIONs) were orthogonally functionalized using receptors bearing multiple hydrogen bonding motifs. …”
Publicado 2021
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92“…Further, the importance of protein-SPION interaction and the successful synthesis of stabilized SPIONs in the amylase enzyme hybrid system are also mentioned. …”
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93por Sillerud, Laurel O“…[Fe]MRI was validated with the samples of superparamagnetic iron oxide nanoparticles (SPIONs) both in agarose gels and bound to human prostate tumor cells. …”
Publicado 2016
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94“…Tissue culture and neutrophil migration assays highlight a dose dependent inflammatory response following SPION exposure which at the imaging dose investigated was not different from controls. …”
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95por Xu, Yujun, Li, Yi, Liu, Xinghan, Pan, Yuchen, Sun, Zhiheng, Xue, Yaxian, Wang, Tingting, Dou, Huan, Hou, Yayi“…SPIONs also increased the level of interleukin-10 (IL-10) in liver macrophages, while SPIONs’s effect on LPS-induced sepsis was abrogated in IL-10(-/-) mice, indicating that the protective effect of SPIONs is dependent on IL-10(+) macrophages. …”
Publicado 2019
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96por Alvear-Jiménez, Alexis, Zabala Gutierrez, Irene, Shen, Yingli, Villaverde, Gonzalo, Lozano-Chamizo, Laura, Guardia, Pablo, Tinoco, Miguel, Garcia-Pinel, Beatriz, Prados, José, Melguizo, Consolación, López-Romero, Manuel, Jaque, Daniel, Filice, Marco, Contreras-Cáceres, Rafael“…Then, we incorporate SPIONs, obtaining a PLGA polymeric matrix containing both Ag(2)S NPs and SPION (PLGA@Ag(2)S@SPION). …”
Publicado 2022
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97por Tashi, Maryam, Shafiee, Behnaz, Sakamaki, Yoshie, Hu, Ji-Yun, Heidrick, Zachary, Khosropour, Ahmad R., Beyzavi, M. Hassan“…The combination of continuous flow technology with immobilizing of only 0.13 mol% of triflic acid (TfOH) on silica-encapsulated superparamagnetic iron oxide nanoparticles (SPIONs) under solvent-free conditions successfully provided a powerful, efficient, and eco-friendly route for the synthesis of plasticizers. …”
Publicado 2018
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98“…By using SPIONs, liver heterogeneity was improved across pre- and post-SPION MRI sessions. …”
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99por Liu, Te, Zhang, Hu, Zheng, Jiajia, Lin, Jiajia, Huang, Yongyi, Chen, Jiulin, Yu, Zhihua, Guo, Lihe, Pan, Weidong, Xiong, Ying, Chen, Chuan“…We used superparamagnetic iron oxide nanoparticles (SPIONs) to mediate the high expression of microRNA‐141 (SPIONs@miR‐141) in human amniotic epithelial stem cells (HuAESCs), which was followed by the induction of the differentiation of HuAESCs into dopaminergic neuron‐like cells (iDNLCs). qPCR, western blot, immunofluorescence staining and HPLC all suggested that SPION‐mediated overexpression of miR‐141 could promote an increased expression of brain‐derived neurotrophic factor (BDNF), DAT and 5‐TH in HuAESC‐derived iDNLCs. …”
Publicado 2018
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100por Amirshaghaghi, Ahmad, Yan, Lesan, Miller, Joann, Daniel, Yonathan, Stein, Joel M., Busch, Theresa M., Cheng, Zhiliang, Tsourkas, Andrew“…In this study, chlorin e6 (Ce6)-coated superparamagnetic iron oxide nanoparticle (SPION) nanoclusters (Ce6-SCs) were prepared via an oil-in-water emulsion. …”
Publicado 2019
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