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  1. 3581
    “…By virtue of this workflow, we conducted a pilot study of 56 cancer patients and 21 healthy individuals using a high-throughput spiral microfluidic chip system. To facilitate genetic discovery of somatic mutations in CTCs, we integrated the CTC enumeration into next-generation sequencing and established a straightforward amplicon library comprising diversifier random sequences to sequence CTC samples. …”
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    Succinct workflows for circulating tumor cells after enrichment: From systematic counting to mutational profiling
  2. 3582
    “…Using marker-independent, low-shear spiral microfluidic technology combined with immunocytochemistry, CTC clusters were found in this patient at the same time point, expressing PD-L1. …”
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    PD-L1 expressing circulating tumour cells in head and neck cancers
  3. 3583
    “…Here, we show that Sestrins were expressed in the inner ear tissues, and Sestrin-2 immunolocalized in sensory hair cells and spiral ganglion (SG). The expression of Sestrin-2 was unchanged, and later downregulated, in gentamicin-treated explants from wild-type mice in vitro. …”
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    Sesn2 gene ablation enhances susceptibility to gentamicin-induced hair cell death via modulation of AMPK/mTOR signaling
  4. 3584
    “…Both the rotation of micro-droplets along the spiral trajectories and the intense eddy diffusion in a hydrocyclone contribute to the extraction intensification.…”
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    Liquid-liquid extraction intensification by micro-droplet rotation in a hydrocyclone
  5. 3585
    “…In the conventional group, the patients received only ASA and clopidogrel. 64-row spiral computed tomographic coronary angiography was performed at 1 week, 1, and 3 months after surgery to evaluate the patency of the graft vessel. …”
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    Preventing graft restenosis after coronary artery bypass grafting with tissue-type plasminogen activator
  6. 3586
    “…We show here that DRP1 self-assembles in two ways: i) in the presence of the non-hydrolysable GTP analog GMP-PNP into spiral-like structures of ~36 nm diameter; and ii) in the presence of GTP into rings composed of 13−18 monomers. …”
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    Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy
  7. 3587
    “…Helicobacter pylori, a spiral-shaped Gram-negative bacterium, has been classified as a class I carcinogen by the World Health Organization and recognized as the causative agent for peptic ulcers, duodenal ulcer, gastritis, mucosa-associated lymphoid tissue lymphomas, and gastric cancer. …”
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    Current knowledge on alleviating Helicobacter pylori infections through the use of some commonly known natural products: bench to bedside
  8. 3588
    “…These show that Cdt1 stabilizes MCM in a left-handed spiral open at the Mcm2–5 gate. We propose that Cdt1 acts as a brace, holding MCM open for DNA entry and bound to ATP until ORC–Cdc6 triggers ATP hydrolysis by MCM, promoting both Cdt1 ejection and MCM ring closure.…”
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    Cdt1 stabilizes an open MCM ring for helicase loading
  9. 3589
    “…METHODS: Different concentrations of urografin, including 2.5%, 5%, 7.5%, 10%, 12.5%, were prepared, and the Hounsfield unit of these solution was measured by two CBCT devices (SORDEX CRANEX 3D and NEWTOM 5G) and one spiral CT device (SOMATOM SENSATION). Difference of output Hounsfield units in each concentration was compared in three devices. …”
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    Accuracy of densitometry of two cone beam computed tomography equipment in comparison with computed tomography
  10. 3590
    “…The following parameters were used: detector configuration – 80×0.5 mm, scanning range in a single spiral acquisition from the skull to the proximal femoral bones, tube voltage – 120 kVp, current tube time product – 86 mAs, slice thickness 1 mm. …”
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    Whole-Body Low-Dose Computed Tomography (WBLDCT) in Assessment of Patients with Multiple Myeloma – Pilot Study and Standard Imaging Protocol Suggestion
  11. 3591
    “…When open reduction is necessary for oblique or spiral extra-articular fractures, lag screw fixation is preferable to plate and screw fixation. …”
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    Treatment of extra-articular proximal and middle phalangeal fractures of the hand: a systematic review
  12. 3592
    “…By taking advantage of our experimental model, we carried out long-term time-lapse observations, which revealed self-assembly, collective migration with leader cells, rotational motion, and spiral motion of epithelial cells in each developmental event. …”
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    In Vitro Experimental Model for the Long-Term Analysis of Cellular Dynamics During Bronchial Tree Development from Lung Epithelial Cells
  13. 3593
    “…In the current study, we use a relatively new ECochG technique to make measurements that originate from afferent auditory nerve fibers in the apical half of the cochlear spiral to assess effects of endolymphatic hydrops in guinea pig ears. …”
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    The Auditory Nerve Overlapped Waveform (ANOW) Detects Small Endolymphatic Manipulations That May Go Undetected by Conventional Measurements
  14. 3594
    “…We also find that absence of Ramp2 leads to failed spiral artery remodeling unaccompanied by changes in the uterine natural killer cell population. …”
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    Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation
  15. 3595
    “…Six Vps4(E233Q) subunits in both assemblies exhibit a spiral-shaped ring-like arrangement. Locating at the periphery of the hexameric ring, Vta1 dimer bridges two adjacent Vps4 subunits by two different interaction modes to promote the formation of the active Vps4 hexamer during ESCRT-III filament disassembly. …”
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    Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution
  16. 3596
    “…The structure and regeneration of the digestive system in the crinoid Himerometra robustipinna (Carpenter, 1881) were studied. The gut comprises a spiral tube forming radial lateral processes, which gives it a five-lobed shape. …”
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    Regeneration of the digestive system in the crinoid Himerometra robustipinna occurs by transdifferentiation of neurosecretory-like cells
  17. 3597
    “…The three UAVs performed seven missions along spiral-like trajectories, most reaching 130 m above take-off location. …”
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    Are estimates of wind characteristics based on measurements with Pitot tubes and GNSS receivers mounted on consumer-grade unmanned aerial vehicles applicable in meteorological studies?
  18. 3598
    “…Substrate-induced domain displacements indicate a pathway of regulated substrate transfer from Hsp70 to the ClpB pore, inside which a spiral of loops contacts the substrate. The seam pore loops undergo marked displacements, along with ordering of the regulatory domains. …”
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    Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase
  19. 3599
    “…In this work, we first formed a subwavelength bright spot and a three-dimensional optical trap under the illumination of an azimuthally polarized (AP) beam by only a single planar element, a spiral zone plate (SZP). Initially, the SZP was proposed as a computer-generated hologram to generate optical phase singularities. …”
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    A subwavelength spot and a three-dimensional optical trap formed by a single planar element with azimuthal light
  20. 3600
    “…We also analyzed tortuosities (spiral twisting of the flow around the flow direction) and bends (the largest angulation in distal part of a stent-graft). …”
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    A new approach for the pre-clinical optimization of a spatial configuration of bifurcated endovascular prosthesis placed in abdominal aortic aneurysms
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