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  1. 4501
    “…CIs target the auditory nerve, consisting of spiral ganglion cells (SGCs), which degenerate gradually, following hair cell loss. …”
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    Combined brain-derived neurotrophic factor and neurotrophin-3 treatment is preferred over either one separately in the preservation of the auditory nerve in deafened guinea pigs
  2. 4502
    “…Decidual vasculopathy are pathological changes in the spiral arteries, which are associated with adverse outcome in preeclampsia and long‐term maternal cardiovascular health. …”
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    The association between decidual vasculopathy and abnormal uterine artery Doppler measurement
  3. 4503
    “…Abbreviations: ABR: auditory brainstem response; ACTB: actin beta; CTSD: cathepsin D; dB: decibel; DFNA67: deafness non-syndromic autosomal dominant 67; DPOAE: distortion product otoacoustic emission; fs: frameshift; GFP: green fluorescent protein; HsQ53R-TG: human p.Q53Rfs*100-transgenic: HEK 293: human embryonic kidney 293; HFD: high-fat diet; KO: knockout; LAMP1: lysosomal associated membrane protein 1; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MTOR: mechanistic target of rapamycin kinase; NSHL: non-syndromic hearing loss; OHC: outer hair cells; OSBPL2: oxysterol binding protein-like 2; SEM: scanning electron microscopy; SGN: spiral ganglion neuron; SQSTM1/p62: sequestosome 1; TEM: transmission electron microscopy; TG: transgenic; WES: whole-exome sequencing; YUHL: Yonsei University Hearing Loss; WT: wild-type.…”
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    OSBPL2 mutations impair autophagy and lead to hearing loss, potentially remedied by rapamycin
  4. 4504
    “…PURPOSE: The stomachs and spiral valves of sharks and rays were examined for their trypanorhynch (Cestoda) parasite fauna and dietary items to infer feeding ecology. …”
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    Elasmobranchs from Indonesian Waters: Feeding Ecology and Trypanorhynch Cestode Fauna Composition to Support Efforts in Shark and Ray Conservation
  5. 4505
    “…We previously demonstrated that intrauterine infection with various strains of P. gingivalis impairs the physiologic remodeling of the uterine spiral arteries (IRSA) during pregnancy, which underlies the major obstetrical syndromes. …”
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    Differential affinity chromatography reveals a link between Porphyromonas gingivalis–induced changes in vascular smooth muscle cell differentiation and the type 9 secretion system
  6. 4506
    “…Embolization was performed using a controlled-release spiral, within two weeks after bypass surgery. Patients were assessed for clinical status, wound healing, median transcutaneous partial pressure of O(2) (TcPO(2)), and post-operative duplex ultrasound evaluating peak systolic velocity (PSV), end diastolic velocity (EDV), and resistance index (RI) to assess foot perfusion and bypass features. …”
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    Duplex and Angiographic-Assisted Evaluation of Outcomes of Endovascular Embolization after Surgical Deep Vein Arterialization for the Treatment No-Option Critical Limb Ischemia Patients
  7. 4507
    “…After deafening, we observed an initial increase in excitability (steeper slope of the eCAP amplitude growth function (AGF), lower threshold, shorter latency and peak width) which typically returned to normal-hearing levels within a week, after which a slower process, probably reflecting spiral ganglion cell loss, took place over the remaining 6 weeks (e.g., decrease in maximum amplitude, AGF slope, peak area, and IPG effect for AGF slope; increase in IPG effect for latency). …”
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    Changes in the Electrically Evoked Compound Action Potential over time After Implantation and Subsequent Deafening in Guinea Pigs
  8. 4508
    “…With 5-week-old male C57BL/6J Gria3-knockout mice (i.e., subunit GluA3(KO)) we determined cochlear function, synapse ultrastructure, and AMPAR molecular anatomy at ribbon synapses between inner hair cells (IHCs) and spiral ganglion neurons. GluA3(KO) and wild-type (GluA3(WT)) mice reared in ambient sound pressure level (SPL) of 55–75 dB had similar auditory brainstem response (ABR) thresholds, wave-1 amplitudes, and latencies. …”
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    GluA3 subunits are required for appropriate assembly of AMPAR GluA2 and GluA4 subunits on cochlear afferent synapses and for presynaptic ribbon modiolar–pillar morphology
  9. 4509
    “…METHODS: We collected information regarding user needs through ethnographic research, direct observation, and semistructured interviews with 37 stakeholders (n=5, 14% physicians; n=1, 3% public health program manager; n=12, 32% community health workers; and n=19, 51% patients) at 2 telemedicine clinics in rural West Bengal, India. We used the Spiral-Iterative Innovation Model to design and develop a prototype solution to meet these needs. …”
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    Development of a Digital Assistant to Support Teleconsultations Between Remote Physicians and Frontline Health Workers in India: User-Centered Design Approach
  10. 4510
    “…PlGF is a protein highly expressed by the placenta with vasculogenic and angiogenic properties, which has a central role in spiral artery remodeling and the development of a low-resistance placental capillary network. …”
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    Perspectives on the Use of Placental Growth Factor (PlGF) in the Prediction and Diagnosis of Pre-Eclampsia: Recent Insights and Future Steps
  11. 4511
    “…Midmodiolar sections of the implanted cochleas were analyzed in terms of trauma to hair cells, modiolar wall, osseous spiral lamina (OSL) and lateral wall. RESULTS: Animals were assigned to cochlear trauma categories: minimal (n = 3), moderate (n = 5), or severe (n = 3). …”
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    Acute effects of cochleostomy and electrode-array insertion on compound action potentials in normal-hearing guinea pigs
  12. 4512
    “…Previous histological studies of humans demonstrated that speech recognition is correlated with spiral ganglion cell counts. Alternatively, ears with good speech recognition outcomes may have good overall neural health, which is a precondition for close electrodes to produce spatially confined neural excitation patterns that facilitate modulation sensitivity. …”
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    Relationship between electrode position and temporal modulation sensitivity in cochlear implant users: Are close electrodes always better?
  13. 4513
    “…The wettability and air moisture harvesting indicated that the genotypes (coded as 1, 7, and 18) having semi-erect to erect leaf angle, spiral rolling, and hydrophilic leaf surface (<90(o)) with contact angle hysteresis less than 10(o) had higher soil moisture content (6-8%) and moisture harvesting efficiency (3.5 ml). …”
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    Leaf wettability and leaf angle affect air-moisture deposition in wheat for self-irrigation
  14. 4514
    por Sugai, H., Ade, P.A.R., Akiba, Y., Alonso, D., Arnold, K., Aumont, J., Austermann, J., Baccigalupi, C., Banday, A.J., Banerji, R., Barreiro, R.B., Basak, S., Beall, J., Beckman, S., Bersanelli, M., Borrill, J., Boulanger, F., Brown, M.L., Bucher, M., Buzzelli, A., Calabrese, E., Casas, F.J., Challinor, A., Chan, V., Chinone, Y., Cliche, J.‑F., Columbro, F., Cukierman, A., Curtis, D., Danto, P., de Bernardis, P., de Haan, T., De Petris, M., Dickinson, C., Dobbs, M., Dotani, T., Duband, L., Ducout, A., Duf, S., Duivenvoorden, A., Duval, J.‑M., Ebisawa, K., Ellefot, T., Enokida, H., Eriksen, H.K., Errard, J., Essinger‑Hileman, T., Finelli, F., Flauger, R., Franceschet, C., Fuskeland, U., Ganga, K., Gao, J.‑R., Génova‑Santos, R., Ghigna, T., Gomez, A., Gradziel, M.L., Grain, J., Grupp, F., Gruppuso, A., Gudmundsson, J.E., Halverson, N.W., Hargrave, P., Hasebe, T., Hasegawa, M., Hattori, M., Hazumi, M., Henrot‑Versille, S., Herranz, D., Hill, C., Hilton, G., Hirota, Y., Hivon, E., Hlozek, R., Hoang, D.‑T., Hubmayr, J., Ichiki, K., Iida, T., Imada, H., Ishimura, K., Ishino, H., Jaehnig, G.C., Jones, M., Kaga, T., Kashima, S., Kataoka, Y., Katayama, N., Kawasaki, T., Keskitalo, R., Kibayashi, A., Kikuchi, T., Kimura, K., Kisner, T., Kobayashi, Y., Kogiso, N., Kogut, A., Kohri, K., Komatsu, E., Komatsu, K., Konishi, K., Krachmalnicof, N., Kuo, C.L., Kurinsky, N., Kushino, A., Kuwata‑Gonokami, M., Lamagna, L., Lattanzi, M., Lee, A.T., Linder, E., Mafei, B., Maino, D., Maki, M., Mangilli, A., Martínez‑González, E., Masi, S., Mathon, R., Matsumura, T., Mennella, A., Migliaccio, M., Minami, Y., Mistuda, K., Molinari, D., Montier, L., Morgante, G., Mot, B., Murata, Y., Murphy, J.A., Nagai, M., Nagata, R., Nakamura, S., Namikawa, T., Natoli, P., Nerval, S., Nishibori, T., Nishino, H., Nomura, Y., Noviello, F., O'Sullivan, C., Ochi, H., Ogawa, H., Ogawa, H., Ohsaki, H., Ohta, I., Okada, N., Okada, N., Pagano, L., Paiella, A., Paoletti, D., Patanchon, G., Piacentini, F., Pisano, G., Polenta, G., Poletti, D., Prouvé, T., Puglisi, G., Rambaud, D., Raum, C., Realini, S., Remazeilles, M., Roudil, G., Rubiño‑Martín, J.A., Russell, M., Sakurai, H., Sakurai, Y., Sandri, M., Savini, G., Scott, D., Sekimoto, Y., Sherwin, B.D., Shinozaki, K., Shiraishi, M., Shirron, P., Signorelli, G., Smecher, G., Spizzi, P., Stever, S.L., Stompor, R., Sugiyama, S., Suzuki, A., Suzuki, J., Switzer, E., Takaku, R., Takakura, H., Takakura, S., Takeda, Y., Taylor, A., Taylor, E., Terao, Y., Thompson, K.L., Thorne, B., Tomasi, M., Tomida, H., Trappe, N., Tristram, M., Tsuji, M., Tsujimoto, M., Tucker, C., Ullom, J., Uozumi, S., Utsunomiya, S., Van Lanen, J., Vermeulen, G., Vielva, P., Villa, F., Vissers, M., Vittorio, N., Voisin, F., Walker, I., Watanabe, N., Wehus, I., Weller, J., Westbrook, B., Winter, B., Wollack, E., Yamamoto, R., Yamasaki, N.Y., Yanagisawa, M., Yoshida, T., Yumoto, J., Zannoni, M., Zonca, A.
    Publicado 2020
    “…The total wide frequency coverage between 34GHz and 448GHz enables us to extract such weak spiral polarization patterns through the precise subtraction of our Galaxy's foreground emission by using spectral differences among CMB and foreground signals. …”
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    Updated design of the CMB polarization experiment satellite LiteBIRD
  15. 4515
    “…This is indicated by larger auditory brainstem responses (ABR) wave I amplitude, which measures afferent spiral ganglion neuron (SGN)-auditory nerve synchrony. …”
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    Sex differences in glutamate AMPA receptor subunits mRNA with fast gating kinetics in the mouse cochlea
  16. 4516
    “…Sildenafil citrate, a phosphodiesterase-5 inhibitor that stabilizes cyclic guanosine monophosphate (cGMP) and increases nitric oxide levels, improves placental perfusion by dilation of spiral arteries and is beneficial in managing IUGR. …”
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    The effects of sildenafil citrate on intrauterine growth restriction: a systematic review and meta-analysis
  17. 4517
    “…In addition, novel risk loci were identified in the proximity of genes involved in the development of placenta (PGR, TRPC6, ACTN4, and PZP), remodeling of uterine spiral arteries (NPPA, NPPB, NPR3, and ACTN4), kidney function (PLCE1, TNS2, ACTN4, and TRPC6), and maintenance of proteostasis in pregnancy serum (PZP). …”
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    Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy
  18. 4518
    “…In the etiology of PE, failure of uterine spiral artery remodeling may be related to functioning abnormally of trophoblast cells, leading to the occurrence and progression of PE. …”
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    Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression
  19. 4519
    “…Voxel-wise maps of short-T2 myelin water fraction (MWF), intermediate-T2 intra/extra-cellular water fraction (IEWF), and long-T2 CSFF were obtained using fast acquisition with spiral trajectory and adiabatic T2prep (FAST-T2) sequence and three-pool non-linear least squares fitting. …”
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    Association of brain tissue cerebrospinal fluid fraction with age in healthy cognitively normal adults
  20. 4520
    “…The fold resembles a chevron badge and is unlike the double-spiral-shaped fold of ALS and type B FTLD-TDP, establishing that distinct filament folds of TDP-43 characterize different neurodegenerative conditions. …”
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    TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
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