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741“…We then examine three types of initial conditions for both TP06 and TNNP04 models and show that the imposition of PD leads to a rich variety of spatiotemporal patterns in the transmembrane potential including states with a single rotating spiral (RS) wave, a spiral-turbulence (ST) state with a single meandering spiral, an ST state with multiple broken spirals, and a state SA in which all spirals are absorbed at the boundaries of our simulation domain. …”
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742por Khoo, Bee Luan, Warkiani, Majid Ebrahimi, Tan, Daniel Shao-Weng, Bhagat, Ali Asgar S., Irwin, Darryl, Lau, Dawn Pingxi, Lim, Alvin S. T., Lim, Kiat Hon, Krisna, Sai Sakktee, Lim, Wan-Teck, Yap, Yoon Sim, Lee, Soo Chin, Soo, Ross A., Han, Jongyoon, Lim, Chwee Teck“…METHODOLOGY/PRINCIPAL FINDINGS: Here, we enriched and characterized putative CTCs from blood samples of patients with both advanced stage metastatic breast and lung cancers using a novel multiplexed spiral microfluidic chip. This system detected putative CTCs under high sensitivity (100%, n = 56) (Breast cancer samples: 12–1275 CTCs/ml; Lung cancer samples: 10–1535 CTCs/ml) rapidly from clinically relevant blood volumes (7.5 ml under 5 min). …”
Publicado 2014
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743“…In this study, a newly developed type of MALDI high-resolution time-of-flight mass spectrometry (TOFMS) with a spiral ion trajectory (MALDI spiral-TOFMS) was applied to the structural and compositional characterization of polymers. …”
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744por Bradford, Russell D., Yoo, Young-Gun, Golemac, Mijo, Pugel, Ester Pernjak, Jonjic, Stipan, Britt, William J.“…Viral antigens were present in the inner ear as were CD3+ mononuclear cells in the spiral ganglion and stria vascularis. Spiral ganglion neuron density was decreased after infection, thus providing a mechanism for hearing loss. …”
Publicado 2015
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745por Froud, Kristina E., Wong, Ann Chi Yan, Cederholm, Jennie M. E., Klugmann, Matthias, Sandow, Shaun L., Julien, Jean-Pierre, Ryan, Allen F., Housley, Gary D.“…Prph((−/−)) mice lacked type II spiral ganglion neuron innervation of the outer hair cells, whereas innervation of the inner hair cells by type I spiral ganglion neurons was normal. …”
Publicado 2015
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746por Schwieger, Jana, Warnecke, Athanasia, Lenarz, Thomas, Esser, Karl-Heinz, Scheper, Verena“…OBJECTIVES: The functionality of cochlear implants (CI) depends, among others, on the number and excitability of surviving spiral ganglion neurons (SGN). The spatial separation between the SGN, located in the bony axis of the inner ear, and the CI, which is inserted in the scala tympani, results in suboptimal performance of CI patients and may be decreased by attracting the SGN neurites towards the electrode contacts. …”
Publicado 2015
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748por Li, Dan, Zhao, Yun-Li, Qin, Xu-Jie, Liu, Lu, Yang, Xing-Wei, Chen, Ying-Ying, Wang, Bei, Wei, Xin, Liu, Ya-Ping, Luo, Xiao-Dong“…The total alkaloids of S. spirale have been screened for their antitussive and expectorant effects in intact animal model. …”
Publicado 2016
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749por Golvano-Escobal, Irati, Gonzalez-Rosillo, Juan Carlos, Domingo, Neus, Illa, Xavi, López-Barberá, José Francisco, Fornell, Jordina, Solsona, Pau, Aballe, Lucia, Foerster, Michael, Suriñach, Santiago, Baró, Maria Dolors, Puig, Teresa, Pané, Salvador, Nogués, Josep, Pellicer, Eva, Sort, Jordi“…Herein, we demonstrate that controlled spatio-temporal patterns, with reproducible spiral-like shapes, can be obtained by electrodeposition of Co-In alloys inside a confined circular geometry (i.e., in disks that are commensurate with the typical size of the spatio-temporal features). …”
Publicado 2016
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750por Suever, Jonathan D, Wehner, Gregory J, Haggerty, Christopher M, Jing, Linyuan, Powell, David, Hamlet, Sean M, Grabau, Jonathan D, Mojsejenko, Dimitri, Andres, Kristin N, Vandsburger, Moriel, Fornwalt, Brandon KEnlace del recurso
Publicado 2016
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751por Yang, Yang, Zhao, Li, Chen, Xiao, Chow, Kelvin, Shaw, Peter W, Gonzalez, Jorge A, Epstein, Frederick H, Meyer, Craig H, Kramer, Christopher M, Salerno, MichaelEnlace del recurso
Publicado 2016
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752“…In terms of cellular and molecular mechanisms underlying this therapeutic effect, additional experiments revealed that spiral ganglion cell survival was significantly improved, mineralocorticoid receptors were upregulated via post-translational protein modifications, and age-related intrinsic and extrinsic apoptotic pathways were blocked by the aldosterone therapy. …”
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753“…The morphology and survival of the cochlear hair cells (HCs) were observed using cochlear surface preparation at 1, 30, 90, 120, 150 and 180 days after moving to the plateau area. Changes in spiral ganglion neurons (SGNs) were detected at different time-points using immunofluorescence technology on frozen sections. …”
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754por Lv, Yinggang, Jin, Yurong, Yan, Qiaohuan, Yuan, Dingling, Wang, Yanling, Li, Xianping, Shen, Yanfeng“…We analyzed the effectiveness of using 64-slice spiral computed tomography (CT) and perfusion imaging to guide argon-helium cryoablation treatment of liver cancer. …”
Publicado 2016
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755por Yadav, Hemant Kumar, Saini, Gaurav Kumar, Chhabra, Harpreet Singh, Panwar, Pratyaksha Singh“…The main objective of this case report is to present a rare root canal configuration of maxillary molar with seven root canals; three mesiobuccal, two palatal and two distobuccal canals diagnosed during treatment procedure confirmed by spiral computed tomography. A thorough knowledge of root canal morphology, proper clinical and radiographic examination, and use of dental operating microscopes are necessary for successful clinical outcomes. …”
Publicado 2017
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756por Hu, Haixia, Ye, Bin, Zhang, Le, Wang, Quan, Liu, Zhiwei, Ji, Suying, Liu, Qiuju, Lv, Jingrong, Ma, Yan, Xu, Ying, Wu, Hao, Huang, Fude, Xiang, Mingliang“…Sensorineural hearing loss (SNHL) is caused by an irreversible impairment of cochlear hair cells and subsequent progressive degeneration of spiral ganglion neurons (SGNs). Eighty-five requiring 3 (Efr3) is a plasma membrane protein conserved from yeast to human, and knockout of Efr3a was reported to facilitate the survival of hippocampal newborn neurons in adult mice. …”
Publicado 2017
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757por Ibarra-Coronado, Elizabeth G., Pérez-Torres, Armando, Pantaleón-Martínez, Ana M., Velazquéz-Moctezuma, Javier, Rodriguez-Mata, Veronica, Morales-Montor, JorgeEnlace del recurso
Publicado 2017
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758por Sang, Xiahan, Lupini, Andrew R., Ding, Jilai, Kalinin, Sergei V., Jesse, Stephen, Unocic, Raymond R.Enlace del recurso
Publicado 2017
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759“…We investigate the effect of mechano-electrical feedback and atrial fibrillation induced electrical remodelling (AFER) of cellular ion channel properties on the dynamics of spiral waves in a discrete 2D model of human atrial tissue. …”
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760“…Spiral waves are shown to undergo directional drifts in the presence of ac and polarized electric fields when their frequencies are twice of the spiral frequencies. …”
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