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2581
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2582“…CiRS-7 silence inhibited OC cell growth and metastasis. CiRS-7 sponged miR-641 to up-regulate ZEB1 and MDM2 expression in OC development. …”
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2583por Chang, Keliang, Wang, Genwei, Lou, Jinfeng, Hao, Sha, Lv, Ranbo, Duan, Desheng, Zhang, Wanhong, Guo, Yingchang, Wang, Pengfei“…Furthermore, we revealed that TTN-AS1 exerted oncogenic effects via sponging miR-27b-3p and thereby positively regulating RUNX1 expression. …”
Publicado 2020
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2584“…Mechanistically, ST7-AS1 functioned as competing endogenous RNA to increase TRPM7 expression by sponging miR-543. Intriguingly, rescue experiments revealed that miR-543 downregulation or TRPM7 overexpression abrogated the inhibitory actions of ST7-AS1 knockdown in the aggressive phenotype of cervical cancer cells. …”
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2585
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2586por Jin, Hui, Li, Chunxue, Dong, Peihong, Huang, Junting, Yu, Jinglu, Zheng, JianjianEnlace del recurso
Publicado 2020
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2587por Chen, Shuifang, Lu, Shan, Yao, Yinan, Chen, Junjun, Yang, Guangdie, Tu, Lingfang, Zhang, Zeying, Zhang, Jianli, Chen, Lina“…Dual luciferase reporter assays indicated that miR-545-3p can bind to hsa_circ_0007580 (suggesting that hsa_circ_0007580 sponges miR-545-3p) and to protein kinase Ca (suggesting that miR-545-3p directly inhibits this gene). …”
Publicado 2020
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2588por Mi, Lili, Lei, Lianhui, Yin, Xiaolei, Li, Ning, Shi, Jianfei, Han, Xin, Duan, Xiaoling, Zhao, Man, Han, Guangjie, Wang, Jinfeng, Yin, Fei“…Conclusion: Our study indicated that circ-0000144 knockdown repressed GC progression at least partly by regulating GPRC5A expression via sponging miR-623, illumining a novel therapeutic target for GC treatment.…”
Publicado 2020
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2589
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2590por Wang, Zhonghai, Zhang, Wenmin, Fang, Jinchuan, Xie, Ping, Miao, Miao, Yang, Hongwen“…Mechanism analysis indicated that upregulation of circEXOC6B increased the level of RUS1 by acting as a competitive “sponge” of miR‐421. CONCLUSION: In this study, we found that circEXOC6B suppressed the growth of ovarian cancer cells through upregulating RSU1 partially via sponging miR-421. …”
Publicado 2020
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2591por Scarfì, Sonia, Pozzolini, Marina, Oliveri, Caterina, Mirata, Serena, Salis, Annalisa, Damonte, Gianluca, Fenoglio, Daniela, Altosole, Tiziana, Ilan, Micha, Bertolino, Marco, Giovine, MarcoEnlace del recurso
Publicado 2020
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2592
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2593por Chen, Dong, Zhang, Min, Ruan, Jian, Li, Xiaolin, Wang, Saisai, Cheng, Xiaofei, Zhao, Huiying, Zeng, Ying, Liu, Jingjing, He, Kangxin, Zhao, Peng“…HOXA11-AS acts as a potential molecular sponge for miR-149-3p, in the promotion of CRC metastasis. …”
Publicado 2020
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2594
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2595por Xiong, Gang, Diao, Dingwei, Lu, Di, Liu, Xiguang, Liu, Zhaoguo, Mai, Shijie, Feng, Siyang, Dong, Xiaoying, Cai, Kaican“…DISCUSSION: circNELL2 promoted the progression of ESCC cells via sponging miR-127-5p, and it has the potential to serve as a novel prognostic and therapeutic target for ESCC.…”
Publicado 2020
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2596“…We thus aim to explore the influence and mechanism of hsa_circ_0128846 in colorectal cancer by sponging its downstream miRNA target miR‐1184. We collected 40 colorectal cancer patients’ tumour tissues to analyse the expression of hsa_circ_0128846, miR‐1184 and AJUBA using qRT‐PCR and Western blot where needed. …”
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2597por Ling, Sunkai, He, Yanru, Li, Xiaoxue, Hu, Mingyue, Ma, Yu, Li, Yuan, Lu, Zipeng, Shen, Shanshan, Kong, Bo, Zou, Xiaoping, Jiang, Kuirong, Huang, Peilin“…In this study, we demonstrated that circRHOT1 was overexpressed in pancreatic cancer tissues and cell lines, and it was found to directly bind to miR‐125a‐3p, acting as an endogenous sponge to inhibit its activity. Knockdown of circRHOT1 expression significantly inhibited proliferation as well as invasion, and it promoted apoptosis of pancreatic cancer cells via the regulation of E2F3 through the targeting of miR‐125a‐3p. …”
Publicado 2020
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2598“…Our results indicate that circZNF292, a down-regulated circRNA in the anterior lens capsule of ARC patients, may be involved in resistance to oxidative damage and apoptosis of lens epithelial cells by sponging miR-23b-3p, providing a potential target for prevention and treatment of ARC.…”
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2599por Chen, Shaoyun, Li, Wenjie, Qu, Bo, Liu, Xiaoying, Wang, Rui, Zhuo, Dongxian, Wu, Lixin“…[Image: see text] The large-scale synthesis of high-purity SiC nanowires is a challenge. In this context, sponge-like graphene oxide (GO) was used as a carbon source as well as a reaction template for directly synthesizing SiC nanowires. …”
Publicado 2020
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