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2701por Zhang, Min, Zhu, Yiqian, Zhu, Jie, Xie, Yi, Wu, Ruihao, Zhong, JiaYin, Qiu, Zhaohui, Jiang, Li“…The mechanism analysis indicated that circ_0086296 sponged miR-576-3p to promote IFIT1–STAT1 expression. …”
Publicado 2022
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2702por Bashari, Muhammad Hasan, Fadhil, Muhammad, Aulia, Yudhi, Sari, Ajeng Kartika, Putri, Tenny, Qomarilla, Nurul, Atmaja, Harold, Sudji, Ikhwan Resmala, Ariyanto, Eko Fuji, Indrati, Agnes Rengga, Rohmawaty, Enny“…OBJECTIVE: To evaluate the potency of the fraction of marine sponge Stylissa carteri in inducing cell death, inhibiting spheroid growth, and its impact on pro-apoptotic protein Mcl-1S in breast cancer cells. …”
Publicado 2022
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2703por Ye, Mengling, Zhao, Lu, Zhang, Lu, Wu, Siyi, Li, Zhao, Qin, Yi, Lin, Fei, Pan, Linghui“…Our results suggested that NALT1 promoted CRC proliferation and migration by sponging miRNA-574-5p to upregulate PEG10 expression, and implied that NALT1 might act as a promising biomarker and therapeutic target for CRC.…”
Publicado 2022
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2704“…Bioactive glass 45S5 bioglass(®) (BG), diatomaceous earth (D.E.) powder, and biosilica (BS) isolated from the Axinella infundibuliformis sponge were chosen as silica-based materials, which were obtained as microparticles and characterized by distinct morphological features. …”
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2705“…Mechanistically, TMEM105 regulated LDHA expression by sponging miR-1208, which further promoted cell glycolysis and BCLM. …”
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2706“…CONCLUSION: Oncogenic function of LINC01503 was dependent on KLK4 upregulation by sponging miR-1321. Revealing the tumor-promoting property of LINC01503 in pancreatic cancer may confer new biomarkers for this malignancy.…”
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2707por Bracegirdle, Joe, Olsen, Stine S. H., Teng, Michael N., Tran, Kim C., Amsler, Charles D., McClintock, James B., Baker, Bill J.“…Respiratory syncytial virus (RSV) is a highly contagious human pathogen that poses a significant threat to children under the age of two, and there is a current need for new small molecule treatments. The Antarctic sponge Suberites sp. is a known source of sesterterpenes, and following an NMR-guided fractionation procedure, it was found to produce several previously unreported metabolites. …”
Publicado 2023
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2708
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2709por Guo, Song, Song, Bingtan, Li, Lin, Li, Hesheng, Yang, Tao, Cao, Lianmeng, Wang, JianEnlace del recurso
Publicado 2023
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2710por Zhang, Weiran, Cao, Cheng, Shen, Jingfu, Shan, Shaoyin, Tong, Yuanhao, Cai, Hongyan, Han, Zhifeng, Chai, Huiping“…All of these findings demonstrate thatLINC01270 is a tumor promotor in LUAD via enhancing LARP1 expressed by sponging miR-326 to facilitate the development of LUAD. …”
Publicado 2023
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2711“…This study provides experimental evidence for the miRNA sponge activity of CYP20A1_Alu-LT in neuronal cell lines. …”
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2712por Lee, Kuan-Yi, Liu, Chia-Ming, Chen, Li-Han, Lee, Chien-Yueh, Lu, Tzu-Pin, Chuang, Li-Ling, Lai, Liang-Chuan“…Moreover, cellular and nuclear fractionation showed that most circAAGAB resided in the cytoplasm and that it up-regulated KIAA1522, NKX3-1, and JADE3 by sponging miR-378 h. Lastly, the functions of circAAGAB were explored by identifying its down-stream genes using Affymetrix microarrays and validated by in vitro assays. …”
Publicado 2023
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2713por Ye, Ling, Shi, Yuan, Zhang, Huifeng, Chen, Chao, Niu, Jingjing, Yang, Jianxu, Li, Zhifeng, Shao, Huanzhang, Qin, Bingyu“…CONCLUSION: Our findings showed that circFLNA promotes intestinal injury in abdominal sepsis through the Fas-mediated apoptosis pathway by sponging miR-766-3p. The circFLNA/miR-766-3p/Fas axis has potential as a novel therapeutic target for treating intestinal injury in sepsis. …”
Publicado 2023
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2714“…Circ_0005273 up‐regulated the expression of HMMR by sponging miR‐509‐3p. Additionally, circ_0005273 silencing might hinder tumor growth in vivo. …”
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2715“…CONCLUSIONS: Overall, PCGEM1 mediated tumor growth and metastasis of OS by sponging miR‐433‐3p and regulating OMA1, which might provide an innovative strategy for OS diagnosis or treatment.…”
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2716por Qu, Yuliang, Jiang, Dan, Liu, Minjuan, Wang, Hongxia, Xu, Tao, Zhou, Haijin, Huang, Minlan, Shu, Weitong, Xu, Guangxian“…After analyzing our experiments, it was found that the data revealed that upregulation of DANCR facilitated the expression of signal transducer and activator of transcription 3, autophagy-related 4D cysteine peptides, autophagy-related 5, Ras homolog enriched in the brain, and microtubule-associated protein 1A/1B light chain 3 (STAT3, ATG4D, ATG5, RHEB, and LC3, respectively) by sponging miR-1301-3p and miR-5194. Immunofluorescence analysis indicated that DANCR played a positive role in both autophagosome formation and fusion of autolysosomes in macrophages. …”
Publicado 2023
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2717por Li, Wenfei, Ke, Chuanfeng, Yang, Cuiyan, Li, Jieyao, Chen, Qikui, Xia, Zhongsheng, Xu, Jihao“…Mechanistically, DICER1‐AS1 functions as a competitive endogenous RNA (ceRNA) that sponges miR‐650 to upregulate MAPK1, promotes ERK1/2 phosphorylation, and sequentially activates the MAPK/ERK signaling pathway. …”
Publicado 2023
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2718“…Mechanistic studies illustrated that XIST directly medullated the VEGFA-mediated autophagy through sponging miR-302b-3p, thereby enhancing the development and progression of HLF. …”
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2720“…Mechanistically, TMEM147-AS1 functioned as a microRNA-326 (miR-326) sponge. Furthermore, SMAD family member 5 (SMAD5) was experimentally validated as the functional effector of miR-326. …”
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