“…BACKGROUND: Animal mitochondrial introns are rare. In sponges and cnidarians they have been found in the cox 1 gene of some spirophorid and homosclerophorid sponges, as well as in the cox 1 and nad 5 genes of some Hexacorallia. …”
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“…The extraction, fractionation and HIV-1 inhibition potential of polysaccharides extracted from three species of marine sponges, Erylus discophorus, Cliona celata and Stelletta sp., collected in the Northeastern Atlantic, is presented in this work. …”
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“…We previously reported that smenospongine, a sesquiterpene aminoquinone isolated from the marine sponge Dactylospongia elegans, showed antiproliferative or cytotoxic activities on leukemia cells. …”
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“…The endemic marine sponge Arenosclera brasiliensis (Porifera, Demospongiae, Haplosclerida) is a known source of secondary metabolites such as arenosclerins A-C. …”
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“…Genomic mining revealed one major nonribosomal peptide synthetase (NRPS) phylogenetic cluster in 12 marine sponge species, one ascidian, an actinobacterial isolate and seawater. …”
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“…Seven new formamido-diterpenes, cavernenes A–D (1–4), kalihinenes E and F (5–6), and kalihipyran C (7), together with five known compounds (8–12), were isolated from the South China Sea sponge Acanthella cavernosa. Structures were established using IR, HRESIMS, 1D and 2D NMR, and single X-ray diffraction techniques. …”
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“…Eight novel cyclic bis-1,3-dialkylpyridiniums, as well as two known compounds from the cyclostellettamine class, were isolated from the sponge Haliclona sp. from Korea. Structures of these novel compounds were determined using combined NMR and FAB-MS/MS analyses. …”
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“…The second new species, Cyamon arguinense sp. n.,possesses polyactine megascleres of which only one of the cladi is spined the remaining three or more cladi being smooth, a feature that is considered characteristic of sponges of the genus Trikentrion. The type species of Cyamon, Cyamon vickersii (Bowerbank) appears to have been misinterpreted as a Caribbean species, because circumstantial evidence strongly indicates an Indian Ocean origin. …”
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“…The most suitable matrix for the immobilization of Bacillus firmus strain 7B was synthetic sponge and for Bacillus sphaericus strain 41 was loofa sponge. …”
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“…Recent studies have unravelled the diversity of sponge-associated bacteria that may play essential roles in sponge health and metabolism. …”
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“…The results also indicated that boring sponges are promoting the dislodgment of live colonies and large fragments from the framework. …”
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“…The hemostatic gelatin sponge loaded with 5-FU was prepared by absorption of the suspension. …”
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“…Cyclostellettamines A – F (1 – 6) isolated from the sponge Pachychalina sp. and cyclostellettamines G - I, K and L (7 – 11) obtained by synthesis were evaluated in bioassays of antimicrobial activity against susceptible and antibiotic-resistant Staphylococcus aureus, Pseudomonas aeruginosa and antibiotic-susceptible Escherichia coli and Candida albicans, as well as in antimycobacterial activity against Mycobacterium tuberculosis H37Rv bioassays. …”
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“…In continuation of our search for drug leads from Red Sea sponges we have investigated the ethyl acetate fraction of the organic extract of the Red Sea sponge Hyrtios species. …”
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“…The patient underwent exploratory laparotomy, sponge removal and became completely asymptomatic. …”
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“…Microbes associated with marine sponges play significant roles in host physiology. …”
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“…Analysis of the deep sea sponge microbiota revealed that the three LMA-like sponges shared a set of abundant OTUs that were distinct from those associated with sponges from shallow waters. …”
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