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9601“…CONCLUSIONS: The hsa_circ_0002130-hsa_miR_4482-3p-NBN interaction network suggested potential sponging miRNA and target mRNA. Our results provided potential functions of circRNAs to explore molecular mechanisms and therapeutic targets in pancreatic cancer cell repopulation upon irradiation.…”
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9602“…Our results revealed that lncRNA MEG3 promoted SOST expression to restrain the progression of AS by sponging let-7i, which provided a treatment target for AS.…”
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9603“…The diverse communities at the mouths of the fjords and in the Central Channel were dominated by large colonies of the Red Tree Coral, Primnoa pacifica, as well as sponges, brachiopods, multiple species of cnidarians, echinoderms, molluscs and arthropods. …”
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9604por Zhou, Jing, Dong, Ze-Ning, Qiu, Bai-Quan, Hu, Ming, Liang, Xiao-Qing, Dai, Xing, Hong, Dan, Sun, Yu-Fang“…Mechanistically, circFGFR3 upregulates E2F1 expression by sponging miR-29a-3p, and the overexpression of E2F1 or the suppression of miR-29a-3p induces OC cell EMT. …”
Publicado 2020
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9605por Wang, Jie, Jiang, Canhua, Li, Ning, Wang, Fei, Xu, Ying, Shen, Zhengzhong, Yang, Lina, Li, Zaiye, He, Caiyun“…OSCC patients with circEPSTI1(high) status exhibited poor prognoses. CircEPSTI1 sponged miR-942-5p and accelerated epithelial-mesenchymal transition (EMT) to increase LTBP2 expression in OSCC through phosphorylation of PI3K/Akt/mTOR signaling pathway components. …”
Publicado 2020
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9606“…CONCLUSIONS: SNHG17 could induce the progression of astrocytoma by sponging miR-876-5p to elevate the expression of ERLIN2. …”
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9607“…Conclusion: Taken together, circ0085539 effectively promoted progression of osteosarcoma through sponging miR-526b-5p to release PHLDA1, strongly suggesting that in vivo intervention of circ0085539–miR-526b-5p–PHLDA1 axis could function as a promising OS-targeted therapy.…”
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9608por Zhu, Kai, Miao, Chenkui, Tian, Ye, Qin, Zhiqiang, Xue, Jianxin, Xia, Jiadong, Zhu, Shenhao, Xu, Aiming, Yang, Jie, Wang, Zengjun“…Long non‐coding RNAs (lncRNAs) take various biological effects in clear cell renal cell carcinoma (ccRCC) mostly through sponging with microRNAs (miRNAs). lncRNA MIR4435‐2HG is found to promote tumour progression in gastric cancer, glioblastoma and hepatocellular carcinoma. …”
Publicado 2020
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9609por Xu, Jing, Wu, Guanghai, Zhao, Yongjie, Han, Youkui, Zhang, Shuai, Li, Chao, Zhang, Judong“…Collectively, DSCAM-AS1 promotes CRC progression via sponging miR-137. MiR-137 can suppress the expression of Notch-1, a novel signaling regulating cell proliferation and EMT, by working on the 3'UTR of Notch-1. …”
Publicado 2020
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9610por Hao, Fengjie, Fei, Xiaochun, Ren, Xinping, Xi Xiao, Joanna, Chen, Yongjun, Wang, Junqing“…In conclusion, pseudogene AKR1B10P1 exerts stabilizing effect on SOX4 in HCC, associated EMT process, by directly sponging miR‐138, which post‐transcriptionally modulates SOX4’s regulating gene.…”
Publicado 2020
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9611por Chen, Feiyu, Zhong, Zhangfeng, Tan, Hor Yue, Guo, Wei, Zhang, Cheng, Cheng, Chien‐Shan, Wang, Ning, Ren, Junguo, Feng, Yibin“…Further investigations demonstrated that lncRNA MALAT1 functioned as a ceRNA (competing endogenous RNA) to contribute to BA‐mediated degradation of IAPs by sponging miR‐22‐3p. Therefore, BA could be developed as a potential anticancer agent for HCC.…”
Publicado 2020
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9612por Li, Wei, Liu, Rengong, Wei, Dongmei, Zhang, Wei, Zhang, Heyan, Huang, Wenjun, Hao, Liguo“…What is more, circ-CCAC1 enhanced C22orf46 expression by sponging miR-514a-5p in ACC cells. A rescue assay illustrated that circ-CCAC1 facilitated ACC progression through miR-514a-5p/C22orf46 signaling. …”
Publicado 2020
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9613“…This venous injury was tackled by further withdrawing the biopsy needle to distal end of the bone marrow tract for tract embolization with coils and gelatin sponges. High caution was made to avoid coil dislodgement into the iliac vein, to prevent pulmonary embolism. …”
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9614por Tito, Claudia, Ganci, Federica, Sacconi, Andrea, Masciarelli, Silvia, Fontemaggi, Giulia, Pulito, Claudio, Gallo, Enzo, Laquintana, Valentina, Iaiza, Alessia, De Angelis, Luciana, Benedetti, Anna, Cacciotti, Jessica, Miglietta, Selenia, Bellenghi, Maria, Carè, Alessandra, Fatica, Alessandro, Diso, Daniele, Anile, Marco, Petrozza, Vincenzo, Facciolo, Francesco, Alessandrini, Gabriele, Pescarmona, Edoardo, Venuta, Federico, Marino, Mirella, Blandino, Giovanni, Fazi, Francesco“…Specifically, we show that LINC00174 favors the expression of SYBU, FEM1B, and SCD5 genes by sponging miR-145-5p, a well-known tumor suppressor microRNA downregulated in a variety of tumors, included TETs. …”
Publicado 2020
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9615por Li, Huaifeng, Hu, Yunping, Jin, Yunpeng, Zhu, Yidi, Hao, Yajuan, Liu, Fatao, Yang, Yang, Li, Guoqiang, Song, Xiaoling, Ye, Yuanyuan, Xiang, Shanshan, Gao, Yuan, Zhu, Jinhui, Zhang, Yijian, Jiang, Lin, Huang, Wen, Zhu, Jian, Wu, Xiangsong, Liu, Yingbin“…Invasion and migration of GBC cells were enhanced through lncGALM, both in vitro and in vivo. lncGALM functioned as sponges by competitively binding to and inactivating miR‐200 family members, which increase epithelial‐mesenchymal transition‐associated transcription factor ZEB1 and ZEB2, leading to a fibroblastic phenotype and increased expression of N‐cadherin. …”
Publicado 2020
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9616por Deng, Zhi-Hai, Yu, Gan-Shen, Deng, Ke-Lei, Feng, Zhen-Hua, Huang, Qiang, Pan, Bin, Deng, Jian-Zhong“…In conclusion, circ_0088233 may function as an oncogene and play an oncogenic role by sponging hsa-miR-185-3p. This study increases the understanding of circRNAs in the progression of prostate cancer. …”
Publicado 2020
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9617por Nosho, Shuji, Tosa, Ikue, Ono, Mitsuaki, Hara, Emilio Satoshi, Ishibashi, Kei, Mikai, Akihiro, Tanaka, Yukie, Kimura-Ono, Aya, Komori, Taishi, Maekawa, Kenji, Kuboki, Takuo, Oohashi, Toshitaka“…In this study, BMP-2 and FGF-2 adsorbed into atellocollagen sponges were transplanted into bone defects in the bone marrow-scarce calvaria (extramedullary environment) and bone marrow-abundant femur (medullary environment) for analysis of their in vivo effects not only on osteoblasts, osteoclasts but also on bone marrow cells. …”
Publicado 2020
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9618por Liu, Yang, Li, Qinshan, Tang, Dongxin, Li, Mengxing, Zhao, Peng, Yang, Wenxiu, Shu, Liping, Wang, Jishi, He, Zhixu, Li, Yanju, Wang, Feiqing“…SNHG17 promoted CRA cell proliferation and migration by sponging miR-23a-3p to upregulate CXCL12. CONCLUSION: SNHG17 promotes the proliferation and migration of CRA cells by inhibiting miR-23a-3p to modulate CXCL12-mediated angiogenesis.…”
Publicado 2020
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9619por Wang, Guixiang, Li, Yajun, Zhu, Hufei, Huo, Guoqiang, Bai, Jingying, Gao, Zhiyong“…Silence of circ-PRKDC impeded CRC progression by sponging miR-198. Overexpression of miR-198 hindered CRC development via targeting DDR1. …”
Publicado 2020
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9620por Li, Bojiang, Feng, Chunyu, Zhu, Shiyu, Zhang, Junpeng, Irwin, David M., Zhang, Xiaoying, Wang, Zhe, Zhang, Shuyi“…Multiple circRNAs can potentially function as sponges of miRNAs that regulate the differentiation of adipocytes. …”
Publicado 2020
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