“…These results revealed that NR2F1-AS1 functioned as an oncogene by sponging miR-641 expression in BC cell progression. …”
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“…Lipopolysaccharide (LPS) was used to establish an NP cell IVDD model. The sponging effect of miR-98 on TRAIL 3′UTR was predicted by ENCORI and assessed by the dual-luciferase reporter gene system. …”
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“…Conclusion: TP73-AS1 promoted GC proliferation, migration, and invasion by sponging miR-27b-3p to regulate TMED5. TP73-AS1 was a potential onco-lncRNA in GC.…”
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“…RESULTS: circLATS2 was highly expressed in HCC and was positively correlated with tumor size and tumor stage. miR-520a-3p was sponged by circLATS2 and was low expressed in HCC tissues. …”
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“…Moreover, we found that GMDS-AS1 and LINC01128 sensitized LUAD cells to CDDP/PEM by sponging miR-6077. Collectively, these results imply the critical role of miR-6077 in LUAD’s sensitivity to CDDP/PEM, thus providing a novel therapeutic strategy for overcoming chemoresistance in clinical practice.…”
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“…Therefore, we concluded that MALAT1 exacerbated MPP(+)-induced neuronal injury through regulating cell viability, apoptosis and inflammatory cytokines by sponging miR-212, providing a novel theoretical foundation for application of MALAT1 in PD.…”
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“…Moreover, GAS5 promoted FOXO3 expression by competitively sponging miR-9. GAS5 knockdown alleviated neuronal cell injury by regulating miR-9/FOXO3, providing a new theoretical foundation for cerebral ischemic stroke.…”
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“…The propagation procedure was performed using plastic autoclavable vented and non-vented vessels, containing porous rooting fine-milled sphagnum peat moss-based sponges, impregnated in ½ Murashige and Skoog liquid growth medium, supplemented with indole-3-butyric acid (IBA) at various concentrations (0, 2.46, 4.92, and 9.84 µM) or by dipping nodal cuttings into 15 mM IBA aqueous solution. …”
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“…Circ_0010235 could regulate the level of HOXA10 by sponging miR-588. CONCLUSION: Circ_0010235 contributed to the malignant progression of NSCLC, but suppressed the radiation sensitivity via targeting miR-588 to induce HOXA10 upregulation.…”
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“…Interestingly, we observed that circKIF4A reprogrammed the glucose metabolism of breast cancer, and silencing circKIF4A greatly affected glucose uptake and lactate production in breast cancer cells. miR-335 can be sponged by circKIF4A, which affected the expression of ALDOA/OCT4 protein and regulated HK2/PKM2 expression. …”
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“…In addition, most DECs have multiple miRNA targets, suggesting that these DECs have the potential to function as miRNA sponges. In conclusion, several DECs are present between pregnant and non-pregnant Jianghuai buffaloes, and these DECs are associated with embryo implantation and pregnancy establishment.…”
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“…INTRODUCTION: Many circRNAs, such as circRNA-0076906 and circRNA-0134944, have been reported to participate in the pathogenesis of osteoporosis via sponging miRNAs in postmenopausal female patients. …”
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“…Our findings showed that LINC01393 sponged miR-128-3p to upregulate NUSAP1, thereby promoting GBM development and progression via activating NF-κB pathway. …”
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“…Mechanistically, FAM83A-AS1 sponged miR-202-3p to regulate the expression of hexokinase II (HK2) in post-transcription, which facilitated the malignancy and glycolysis. …”
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“…A series of follow‐up studies have shown that SNHG4 promoted the progression and malignancy of HCC through upregulating CREB5 via sponging miR‐211‐5p. CONCLUSION: Collectively, the above findings suggest that SNHG4 promotes HCC malignancy through the SNHG4/miR‐211‐5p/CREB5 axis, providing potential therapeutic targets and prognostic factors for HCC. …”
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“…Additionally, SOX2OT upregulated METTL3/14/IGF2BP2 by sponging miR-186-5p. Functional analysis corroborated that GLI1 acted as a downstream target of METTL3/14/IGF2BP2, and GLI1 silencing could block the oncogenicity of lung cancer stem-like cells. …”
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“…CircRNAs have been demonstrated to contribute to the pathogenesis of breast cancer including its initiation, progression, metastasis, and resistance to drugs. By acting as miRNA sponges, circRNAs can indirectly influence gene expression by disrupting miRNA regulation of their target genes, ultimately altering the course of cancer development and progression. …”
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“…CONCLUSION: In conclusion, NEAT1 was increased in MPP(+)‐induced SH‐SY5Y cells, and it promoted MPP(+)‐induced pyroptosis through facilitating YAF2 expression by sponging miR‐5047.…”
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“…Dual luciferase reporter confirmed that FALEC sponges miR-20a-5p and down-regulated its expression. …”
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