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  1. 9881
    “…Mechanistically, LINC01559 sponged miR-1343-3p to upregulate PGK1 (phosphoglycerate kinase 1), therefore activating PI3K/AKT pathway. …”
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    Exosome-transferred LINC01559 promotes the progression of gastric cancer via PI3K/AKT signaling pathway
  2. 9882
    “…They behave as competitive endogenous RNA (ceRNA), acting as natural miRNA sponges to inhibit miRNA functions and modulate the expression of RNA messenger (mRNA). …”
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    miRTissue (ce): extending miRTissue web service with the analysis of ceRNA-ceRNA interactions
  3. 9883
    “…DISCUSSION: Our results provided evidence that PART1 serves as oncogenic lncRNA through sponging miR-590-3p to upregulate HMGB2 expression in HCC.…”
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    Long Noncoding RNA PART1 Promotes Hepatocellular Carcinoma Progression via Targeting miR-590-3p/HMGB2 Axis
  4. 9884
    “…It was further revealed that circRNA_0000491 sponged miR-101b and that miR-101b directly targets TGFβRI. …”
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    A novel identified circular RNA, circ_0000491, aggravates the extracellular matrix of diabetic nephropathy glomerular mesangial cells through suppressing miR-101b by targeting TGFβRI
  5. 9885
    “…Through performing a series of in vitro and in vivo experiments, we found that circ-PGAP3 promoted TNBC cell growth and metastasis via sponging and inhibiting miR-330-3p, resulting in the upregulation of proto-oncogene Myc. …”
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    The Novel Circular RNA Circ-PGAP3 Promotes the Proliferation and Invasion of Triple Negative Breast Cancer by Regulating the miR-330-3p/Myc Axis
  6. 9886
    “…Our data describe that KCNQ1OT1 is responsible for SBRT resistance in LUAD through induction of ATG5- and ATG12-dependent autophagy via sponging miR-372-3p, which would be a potential strategy to enhance the antitumor effects of radiotherapy in LUAD.…”
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    Upregulation of KCNQ1OT1 promotes resistance to stereotactic body radiotherapy in lung adenocarcinoma by inducing ATG5/ATG12-mediated autophagy via miR-372-3p
  7. 9887
    “…Further studies found that LINC00470 regulated MYC by sponging miR‐134 to regulate the expression of ABCC1. …”
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    LINC00470 promotes tumour proliferation and invasion, and attenuates chemosensitivity through the LINC00470/miR‐134/Myc/ABCC1 axis in glioma
  8. 9888
    “…In conclusion, the findings of the present study indicated that RP11-619L19.2 regulates CD164 expression and EMT by sponging miR-1271-5p, which may provide novel targets for lncRNA-directed diagnosis and therapy for patients with CC.…”
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    RP11-619L19.2 promotes colon cancer development by regulating the miR-1271-5p/CD164 axis
  9. 9889
    “…MiR-663a inhibited apoptosis by repressing PLA2G6 expression, while circABCC4 enhanced the apoptosis and inhibited the proliferation of A549 cells by sponging miR-663a and increasing PLA2G6 expression. …”
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    Promotion of Bronchopulmonary Dysplasia Progression Using Circular RNA circabcc4 via Facilitating PLA2G6 Expression by Sequestering miR-663a
  10. 9890
    “…Notably, circ_0008450 regulated AKAP1 expression by sponging miR-431. Furthermore, miR-431 inhibition reversed the circ_0008450 silencing-mediated effects on viability, apoptosis and glycolysis in hypoxia-treated HCC cells. …”
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    Hypoxia-induced circular RNA hsa_circ_0008450 accelerates hepatocellular cancer progression via the miR-431/AKAP1 axis
  11. 9891
    “…Most known Pennsylvanian tropical reefs and mounds are predominantly composed of calcareous algae (e.g. phylloid algae, Archaeolithophyllum), calcareous sponges, fenestrate bryozoans, Tubiphytes, and microbialites. …”
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    Late Pennsylvanian carbonate platform facies and coral reef: new insights from southern China (Guizhou Province)
  12. 9892
    “…Mechanistically, we found that cCNTNAP3 promotes the expression of p53 by sponging miR-513a-5p. Rescue assay confirmed that the suppressive function of cCNTNAP3 was dependent on miR-513a-5p. …”
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    CircCNTNAP3-TP53-positive feedback loop suppresses malignant progression of esophageal squamous cell carcinoma
  13. 9893
    por Wang, Yu, Fu, Jianying, Yang, Lili, Liang, Zhi
    Publicado 2021
    “…Taken together, the results revealed that SNHG20 facilitated CRC progression by regulating STAT3 expression and by sponging miR-495.…”
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    Long non-coding RNA SNHG20 promotes colorectal cancer cell proliferation, migration and invasion via miR-495/STAT3 axis
  14. 9894
    “…CONCLUSION: SNHG10 was transcriptionally activated by ETS1 and played an oncogenic role in glioma by sponging miR-532-3p and up-regulating FBXL19. [Image: see text]…”
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    ETS1-activated SNHG10 exerts oncogenic functions in glioma via targeting miR-532-3p/FBXL19 axis
  15. 9895
    “…We further demonstrated that H19 sponged miRNA-130a-3p, which resulted in SATB1 upregulation, thus promoting BC progression. …”
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    H19 Knockdown Suppresses Proliferation and Induces Apoptosis by Regulating miR-130a-3p/SATB1 in Breast Cancer Cells
  16. 9896
    “…Luciferase reporter assays revealed that NEAT1 up-regulated SMAD2 by directly sponging miR-200b-3p. In vitro and in vivo, we demonstrated that both NEAT1 and SMAD2 could promote the proliferation and invasion of melanoma cells, and these effects were reversed by up-regulating miR-200b-3p. …”
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    NEAT1/miR-200b-3p/SMAD2 axis promotes progression of melanoma
  17. 9897
    “…Most of the studied circRNAs in BCa regulate cancer biological behaviours via miRNA sponging regulatory mechanisms. CircRNAs have been reported to be significantly associated with many clinicopathologic characteristics of BCa, including tumour size, grade, differentiation, and stage; lymph node metastasis; tumour numbers; distant metastasis; invasion; and recurrence. …”
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    Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer
  18. 9898
    “…Finally, we showed KCNQ1OT1/miR-4319/DRAM2 axis regulates GC cell growth in vitro and in vivo. lncRNA KCNQ1OT1 promotes GC progression by sponging miR-4319 to upregulate DRAM2, indicating KCNQ1OT1 might be a promising target for GC treatment.…”
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    KCNQ1OT1 accelerates gastric cancer progression via miR-4319/DRAM2 axis
  19. 9899
    “…Mechanistic studies revealed that TUSC7 exerted its role by sponging microRNA (miR)-181a in OS cell lines. Ras association domain family member 6 (RASSF6) was confirmed as a target gene of miR-181a, and the expression levels of RASSF6 were negatively regulated by miR-181a. …”
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    lncRNA TUSC7 inhibits osteosarcoma progression through the miR-181a/RASSF6 axis
  20. 9900
    “…Functional and biochemical experiments in BCa cell lines including luciferase reporter assays showed that MAGI2-AS3 upregulated TNS1 by sponging miR-31-5p. Transwell assays showed that the MAGI2-AS3/miR-31-5p/TNS1 axis regulated migration and invasion ability of BCa cell lines. …”
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    LncRNA MAGI2-AS3 inhibits bladder cancer progression by targeting the miR-31-5p/TNS1 axis
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