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  1. 10001
    “…A restoration assay suggested that MCF2L-AS1 promoted LUAD cell growth by sponging miR-874-3p and modulating STAT3 expression. …”
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    MCF2L-AS1/miR-874-3p/STAT3 feedback loop contributes to lung adenocarcinoma cell growth and cisplatin resistance
  2. 10002
    “…FMO2 served as a downstream target of miR‐421 and circ_MACF1 sponged miR‐421 to elevate the expression of FMO2. …”
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    Circ_MACF1 targets miR‐421 to upregulate FMO2 to suppress paclitaxel resistance and malignant cellular behaviors in lung adenocarcinoma
  3. 10003
    “…BACKGROUND: Tissue plasticity and a substantial regeneration capacity based on stem cells are the hallmark of several invertebrate groups such as sponges, cnidarians and Platyhelminthes. Traditionally, Acoela were seen as an early branching clade within the Platyhelminthes, but became recently positioned at the base of the Bilateria. …”
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    Characterization of the stem cell system of the acoel Isodiametra pulchra
  4. 10004
    “…ErbB3, and EGFR orthologs in sponges and parasitic worms, diverge from some of the canonical ErbB features, providing insights into sub-family and lineage-specific functional specialization. …”
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    Co-Conserved Features Associated with cis Regulation of ErbB Tyrosine Kinases
  5. 10005
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    Progestogens to prevent preterm birth in twin pregnancies: an individual participant data meta-analysis of randomized trials
  6. 10006
    “…In the present study, we investigated the effects of scalaradial and cacospongionolide, two sesterterpenoids from Cacospongia scalaris and Fasciospongia cavernosa marine sponges, on the apoptotic signalling pathway in three different human tumoral cells. …”
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    Cacospongionolide and Scalaradial, Two Marine Sesterterpenoids as Potent Apoptosis-Inducing Factors in Human Carcinoma Cell Lines
  7. 10007
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    Prenatal Treatment Prevents Learning Deficit in Down Syndrome Model
  8. 10008
    “…NALCN is a highly conserved gene from simple, extant multicellular organisms without nervous systems such as sponges and placozoans and mostly remains a single gene compared to the calcium and sodium channels which diversified into twenty genes in humans. …”
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    NALCN Ion Channels Have Alternative Selectivity Filters Resembling Calcium Channels or Sodium Channels
  9. 10009
    “…Site differences in carbon fixation pathways were traced into higher trophic levels e.g. a stichasterid asteroid that predates on Kiwa sp. Sponges and anemones at the periphery of E2 assimilated a proportion of epipelagic photosynthetic primary production but this was not observed at E9N. …”
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    Spatial Differences in East Scotia Ridge Hydrothermal Vent Food Webs: Influences of Chemistry, Microbiology and Predation on Trophodynamics
  10. 10010
    “…The genetic and epigenetic mechanisms that regulate the expression of these microRNAs as well as the role of the recently described natural RNA circles which act as natural microRNA sponges regulating post-transcriptional microRNA expression and function during the early stages of neurogenesis is also discussed.…”
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    microRNAs: key triggers of neuronal cell fate
  11. 10011
    “…One of the holothurian assemblages was part of the rich macrozoobenthic community dominated by a diverse and abundant epifauna, mainly sponges and gorgonians. Another one was mainly composed of vagrant deposit-feeding species inhabiting a predominantly non-colonised substratum. …”
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    Asteroids, ophiuroids and holothurians from the southeastern Weddell Sea (Southern Ocean)
  12. 10012
    “…A SCI model was established by surgery via a complete transection of the T10 vertebra of female Sprague-Dawley rats. Gelatin sponges were used to absorb NSCs labeled with the thymidine analog, 5-bromo-2-deoxyuridine (BrdU), and were transferred into the transected spinal cords. …”
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    Synergistic effects of Buyang Huanwu decoction and embryonic neural stem cell transplantation on the recovery of neurological function in a rat model of spinal cord injury
  13. 10013
    “…This information can be used to more formally develop water quality thresholds for benthic organisms, such as corals, filter-feeders (e.g. sponges) and seagrasses in future laboratory- and field-based studies using environmentally realistic and relevant exposure scenarios, that may be used to further refine distance based analyses of impact, potentially further reducing the size of the dredging footprint.…”
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    Spatial Patterns in Water Quality Changes during Dredging in Tropical Environments
  14. 10014
    “…Of particular importance are organisms like sponges and macroalgae and their associated microbiome. …”
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    Planctomycetes as Novel Source of Bioactive Molecules
  15. 10015
    “…RESULTS: Given recently discovered differences in developmental toolkit components between siliceous and calcareous sponges, we have carried out genome-wide analysis of bHLH genes in Sycon ciliatum, an emerging calcisponge model. …”
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    Conservation and divergence of bHLH genes in the calcisponge Sycon ciliatum
  16. 10016
    “…The long intergenic non-coding RNA ROR (lincRNA-ROR, linc-ROR) acts as a regulator of cellular reprograming through sponging miR-145 that normally negatively regulates the expression of the stemness factors NANOG, OCT4, and SOX2. …”
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    Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma
  17. 10017
    “…Group I introns and HEGs are rare in metazoans, and can be mainly found inserted in the COXI gene of some sponges and cnidarians, including stony corals (Scleractinia) and mushroom corals (Corallimorpharia). …”
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    Evolutionary and biogeographical implications of degraded LAGLIDADG endonuclease functionality and group I intron occurrence in stony corals (Scleractinia) and mushroom corals (Corallimorpharia)
  18. 10018
    “…Importantly, we also found GATA3 transcriptionally actives miR-506-3p expression, and the long non-coding RNA urothelial carcinoma-associated 1 (UCA1) exerts oncogenic function in NSCLC by competitively ‘sponging’ miRNA-506. Together, our combined results elucidated genetic and epigenetic silencing of miR-506-3p enhances COTL1 oncogene expression to foster NSCLC progression.…”
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    Genetic and epigenetic silencing of mircoRNA-506-3p enhances COTL1 oncogene expression to foster non-small lung cancer progression
  19. 10019
    “…These features confer numerous potential functions to circRNAs, such as acting as miRNA sponges, or binding to RNA-associated proteins to form RNA-protein complexes that regulate gene transcription. …”
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    Circular RNAs: Biogenesis, Function and Role in Human Diseases
  20. 10020
    “…RESULTS: Cortactin homologues exist in sponges, worms, shrimps, insects, urochordates, fishes, amphibians, birds and mammalians, whereas HS1 exists in vertebrates only, suggesting that both genes have been derived from an ancestor cortactin gene by duplication. …”
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    Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain
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