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10561por Xu, Congjie, Liang, Hui, Zhou, Jiaquan, Wang, Yang, Liu, Shuan, Wang, Xiaolin, Su, Liangju, Kang, Xinli“…The results of the luciferase reporter assay suggested that SNHG12 exerted its role by sponging microRNA (miR)-200c-5p, which led to the upregulation of its target gene, collagen type XI α1 chain (COL11A1). …”
Publicado 2020
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10562“…Circ-ELF2 upregulated MUC15 by sponging miR-510-5p, thus promoting GM growth and aggressiveness. …”
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10563“…BACKGROUND: Circular RNAs (circRNAs) have been deemed to be microRNA (miRNA) sponges that are involved in multiple biological processes. …”
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10564por Chen, Yangming, Lei, Yujie, Lin, Jianbin, Huang, Yunchao, Zhang, Jiguang, Chen, Kai, Sun, Shihui, Lin, Xing“…The effects of LINC01260 were exerted by regulating CYLD via sponging miR-562. ELISA confirmed that the upregulation of CYLD inhibited NF-κB activity; however, the co-transfection of sh-LINC01260 partly reversed the inhibition. …”
Publicado 2020
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10565por Li, Fengmin, Xian, Zhihan, Kwon, Hee Jin, Yoo, Jiyoon, Burall, Laurel, Chirtel, Stuart J., Hammack, Thomas S., Chen, Yi“…We then sampled Lm with sponges pre-moistened in three transport broths, Dey/Engley (D/E) broth, Letheen broth and HiCap™ broth, to generate environmental samples that contained sanitizer residues and low levels of stressed Lm, which were subsequently analyzed by an enrichment-based method. …”
Publicado 2020
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10566por Peng, Lei, Sang, Huaiming, Wei, Shuchun, Li, Yuanyuan, Jin, Duochen, Zhu, Xudong, Li, Xuan, Dang, Yini, Zhang, Guoxin“…In the AGS and SGC-7901 cell lines, circCUL2 sponged miR-142-3p to regulate ROCK2, thus modulating tumor progression. …”
Publicado 2020
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10567“…CONCLUSION: This study demonstrated that circ_0072995 promoted cell malignant phenotypes and anaerobic glycolysis in breast cancer via up-regulating SHMT2 through sponging miR-149-5p, indicating a promising molecular target for breast cancer treatment.…”
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10568por Gao, Wei, Guo, Huina, Niu, Min, Zheng, Xiwang, Zhang, Yuliang, Xue, Xuting, Bo, Yunfeng, Guan, Xiaoya, Li, Zhongxun, Guo, Yujia, He, Long, Zhang, Yu, Li, Li, Cao, Jimin, Wu, Yongyan“…We further revealed that activation of the PRKCI-Akt-mTOR pathway through sponging miR-145-5p was the main mechanism of circPARD3 inhibited autophagy, promoting LSCC progression and chemoresistance. …”
Publicado 2020
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10569LncRNA ST7-AS1, by regulating miR-181b-5p/KPNA4 axis, promotes the malignancy of lung adenocarcinomapor Hu, Rong-Hang, Zhang, Zi-Teng, Wei, Hai-Xiang, Ning, Lu, Ai, Jiang-Shan, Li, Wen-Hui, Zhang, Heng, Wang, Shao-Qiang“…The oncogenic activities of ST7-AS1 were accomplished by sponging miR-181b-5p and releasing the suppression of the latter on KPNA4. …”
Publicado 2020
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10570por Nweze, Justus Amuche, Mbaoji, Florence N., Li, Yan-Ming, Yang, Li-Yan, Huang, Shu-Shi, Chigor, Vincent N., Eze, Emmanuel A., Pan, Li-Xia, Zhang, Ting, Yang, Deng-Feng“…These compounds were all isolated from bacteria, a fungus, sponges, algae, a bryozoan, cnidarians and soft corals. …”
Publicado 2021
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10571por Zhang, Ming, Wang, Yan, Jiang, Longyang, Song, Xinyue, Zheng, Ang, Gao, Hua, Wei, Minjie, Zhao, Lin“…Mechanistically, we identified that CBR3-AS1 functioned as a competitive endogenous RNA by sponging miR-25-3p. MEK4 and JNK1 of the MAPK pathway were determined to be direct downstream proteins of the CBR3-AS1/miR-25-3p axis in breast cancer cells. …”
Publicado 2021
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10572por Wu, Jie, Zheng, Chunlei, Wang, Yizhe, Yang, Zichang, Li, Ce, Fang, Wanxia, Jin, Yue, Hou, Kezuo, Cheng, Yang, Qi, Jianfei, Qu, Xiujuan, Liu, Yunpeng, Che, Xiaofang, Hu, Xuejun“…Mechanistically, APCDD1L-AS1 promoted icotinib resistance and EGFR upregulation by sponging with miR-1322/miR-1972/miR-324-3p to remove the transcription inhibition of SIRT5. …”
Publicado 2021
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10573“…CONCLUSION: LINC00885 upregulated MACC1 expression in cervical cancer cells by sponging miR-432-5p, thereby promoting cancer progression. …”
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10574“…CircGDI2 overexpression could effectively inhibit the proliferation, migration, invasion and promote apoptosis in OSCC cells, and suppress OSCC tumor growth in nude mice in vivo. MiR-454-3p could be sponged by circGDI2, and its overexpression could mitigate the suppressive effects of circGDI2 overexpression on OSCC progression. …”
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10575por Li, Shanshan, Liu, Yize, Qiu, Guanzhen, Luo, Yinzhou, Luan, Lan, Xu, Tiance, Wang, Yong, Xia, Shuyue“…CONCLUSION: CAR10 promoted NSCLC cell migration and invasion by upregulating GJB2 and sponging miR-892a. These findings illustrated that the CAR10/miR-892a/GJB2 axis may be a novel molecular target for the treatment of NSCLC.…”
Publicado 2021
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10576“…Mechanically, NOP14-AS1 functioned as a competing endogenous RNA by sponging microRNA-665 (miR-665), thereby overexpressing the target high mobility group box 3 (HMGB3) of miR-665. …”
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10577por Muchová, Johana, Hearnden, Vanessa, Michlovská, Lenka, Vištejnová, Lucie, Zavaďáková, Anna, Šmerková, Kristýna, Kočiová, Silvia, Adam, Vojtěch, Kopel, Pavel, Vojtová, Lucy“…Moreover, we suggest that these sponges could be used as scaffolds for growing cells in systems with low mechanical loading in tissue engineering, especially in dermis replacement, where neovascularization is a crucial parameter for successful skin regeneration. …”
Publicado 2021
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10578“…The mechanism studies confirmed that LIPE-AS1 sponges miR-195-5p as a competitive endogenous RNA (ceRNA), which targets the 3′-untranslated region (3′-UTR) of MAP3K8. …”
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10579“…Depletion of hsa_circ_0000144 could inhibit OXA resistance, proliferation and metastasis in OXA-resistant GC cells, which was attenuated by miR-502-5p inhibition. Hsa_circ_0000144 sponged miR-502-5p to positively regulate ADAM9 expression. …”
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10580por Le Joncour, Vadim, Guichet, Pierre-Olivier, Dembélé, Kleouforo-Paul, Mutel, Alexandre, Campisi, Daniele, Perzo, Nicolas, Desrues, Laurence, Modzelewski, Romain, Couraud, Pierre-Olivier, Honnorat, Jérôme, Ferracci, François-Xavier, Marguet, Florent, Laquerrière, Annie, Vera, Pierre, Bohn, Pierre, Langlois, Olivier, Morin, Fabrice, Gandolfo, Pierrick, Castel, Hélène“…In mouse-transplanted Matrigel sponges, mouse (mUII) and human UII markedly stimulated invasion by macrophages, endothelial, and smooth muscle cells. …”
Publicado 2021
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