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10721por Jun, Wang, Shaobo, Ouyang, Xianhua, Zhang, Siyu, Zhao, Mingyang, Cheng, Xin, Fan, Ying, Cai, Lan, Liao“…By observing the effect of different miRNAs on the levels of circ_0001847 and circ_0001971, it was identified that circ_0001847 and circ_0001971 respectively sponged the expression of miR-296 and miR-186 via binding to these miRNAs. …”
Publicado 2021
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10722“…Besides, we confirmed that miR-338-3p directly sponged with CHL1 to mediate tumor cells progression. …”
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10723“…LINC00491 facilitated liver cancer progression by sponging miR-324-5p/ROCK1. LINC00491 might be a potential treatment target of liver cancer.…”
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10724por Wang, Zehao, Yang, Lu, Wu, Peng, Li, Xing, Tang, Yuhui, Ou, Xueqi, Zhang, Yue, Xiao, Xiangsheng, Wang, Jin, Tang, Hailin“…Further research revealed that circROBO1 could upregulate KLF5 by sponging miR-217-5p, allowing KLF5 to activate the transcription of FUS, which would promote the back splicing of circROBO1. …”
Publicado 2022
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10725por Chen, Qingshi, Lin, Guofu, Lin, Lanlan, Huang, Jiefeng, Chen, Lida, Lian, Ningfang, Chen, Mengxue, Zeng, Aiming, Lin, Qichang“…The roles of XR_596701 were achieved by sponging miR-344b-5p. And the function of miR-344b-5p was reversed by targeting FAIM3. …”
Publicado 2022
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10726“…LncRNA SND1-IT1 participated in TGF-β1-stimulated EMT in GC by sponging miR-124. MiR-124 attenuated TGF-β1-stimulated EMT in GC by targeting COL4A1. …”
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10727por Guo, Feng, Tang, Chengchun, Huang, Bo, Gu, Lifei, Zhou, Jun, Mo, Zongyang, Liu, Chang, Liu, Yuqing“…The dual luciferase reporter gene assay was carried out to detect the sponging relationship between H19 and miR-29a/b-3p in CFs. …”
Publicado 2022
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10728“…Furthermore, circRbms1 sponged miR-742-3p. MiR-742-3p overexpression alleviated hypoxia-induced cardiomyocyte injury, and its inhibitor reversed the suppressive effect of circRbms1 silencing on hypoxia-induced cardiomyocyte injury. …”
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10729por Zhang, Fangbin, Guo, Changqing, Cao, Xinguang, Yan, Yan, Zhang, Jinping, Lv, Shuai“…GC-derived EVs led to increased HPMC apoptosis and MMT by transferring SNHG12, whereas the knockdown of SNHG12 annulled the aforementioned results. SNHG12 sponged miR-129-5p to boost E2F7 expression and activate the MAPK/ERK signaling, thus inducing HPMC apoptosis and MMT. …”
Publicado 2022
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10730por Xu, Jia, Wang, Qin, Song, Yi-Fan, Xu, Xiao-Hui, Zhu, He, Chen, Pei-Dan, Ren, Ye-Ping“…Mechanistically, XIST sponged miR-15b-5p to regulate TLR4. Silencing XIST inhibited TLR4 by promoting miR-15b-5p. miR-15b-5p inhibition or TLR4 overexpression averted the inhibitory effect of silencing XIST on HG-induced RTEC pyroptosis. …”
Publicado 2022
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10731por Du, Ashuai, Li, Shiqin, Zhou, Yuzheng, Disoma, Cyrollah, Liao, Yujie, Zhang, Yongxing, Chen, Zongpeng, Yang, Qinglong, Liu, Pinjia, Liu, Sixu, Dong, Zijun, Razzaq, Aroona, Tao, Siyi, Chen, Xuan, Liu, Yuxin, Xu, Lunan, Zhang, Qianjun, Li, Shanni, Peng, Jian, Xia, Zanxian“…Mechanistically, circMDK sponged miR-346 and miR-874-3p to upregulate ATG16L1 (Autophagy Related 16 Like 1), resulting to the activation of PI3K/AKT/mTOR signaling pathway to promote cell proliferation, migration and invasion. …”
Publicado 2022
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10732por Zhang, Ling-Xian, Gao, Jian, Long, Xiang, Zhang, Peng-Fei, Yang, Xin, Zhu, Shu-Qiang, Pei, Xu, Qiu, Bai-Quan, Chen, Shi-Wei, Lu, Feng, Lin, Kun, Xu, Jian Jun, Wu, Yong-Bing“…Mechanistically, circHMGB2 relieves the inhibition of downstream CARM1 by sponging miR-181a-5p, thus inactivating the type 1 interferon response in the LUAD and LUSC. …”
Publicado 2022
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10733“…Additionally, HCP5 inhibited IL-13-induced GM-CSF, eotaxin, and MUC5AC production in NECs. HCP5 sponged miR-16 and negatively regulated its expression, and miR-16 targeted ATXN2L and inhibition of miR-16 suppressed IL-13-induced GM-CSF, eotaxin, and MUC5AC expression. …”
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10734por Shen, Siman, Liu, Keyu, Li, Simeng, Rampes, Sanketh, Yang, Yuhui, Huang, Yifeng, Tang, Jing, Xia, Zhengyuan, Ma, Daqing, Zhang, Liangqing“…Based on our MeRIP-qPCR experiment data, both lncGm15328 and lncRNA Zfp597, that were not previously associated with cardiac regeneration, were found to be the most differently methylated at P1-P7. These two lncRNAs sponged several miRNAs which further regulated multiple mRNAs, including some of which have previously been linked with cardiac regeneration ability. …”
Publicado 2022
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10735“…RESULTS: CircDIDO1 inhibited GC progression by regulating the expression of the signal transducer inhibitor SOSC2 through sponging miR-1307-3p. Overexpression of circDIDO1 or SOSC2 antagonized the oncogenic role of miR-1307-3p. …”
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10736por Zhang, Yuanyuan, Wang, Shaojun, Guo, Sicong, Zhang, Xinzhong, Yang, Chuan, Su, Guangsheng, Wan, Jiye“…ROCK2 was the target of miR-942-5p and circ_0004104 regulated the expression of ROCK2 through sponging miR-942-5p. ROCK2 abated the influences of miR-942-5p in ox-LDL-stimulated HUVECs. …”
Publicado 2022
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10737“…However, when juxtaposed to unassisted healing or socket filling using collagen sponges, the application of biologics did contribute to attenuate post‐extraction alveolar ridge atrophy in most investigations. …”
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10738por Thiele, Lisa R., Duryea, Elaine L., Ragsdale, Alexandra S., Berge, Carrie A., McIntire, Donald D., Nelson, David B., Spong, Catherine Y.Enlace del recurso
Publicado 2023
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10739por Zichittella, Chiara, Loria, Marco, Celesia, Adriana, Di Liberto, Diana, Corrado, Chiara, Alessandro, Riccardo, Emanuele, Sonia, Conigliaro, Alice“…Finally, bioinformatics analyses were used to identify miRNAs targeting pro-apoptotic factors that can be sponged by lncH19. Results: ITF2357 increased the expression levels of H19 and reduced HCT-116 cell viability, inducing apoptosis, as demonstrated by the increase in annexin-V positivity, caspase 3 cleavage, and poly (ADP-ribose) polymerase (PARP-1) degradation. …”
Publicado 2023
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10740por Castrén, Eeva, Sillat, Tarvo, Oja, Sofia, Noro, Ariel, Laitinen, Anita, Konttinen, Yrjö T, Lehenkari, Petri, Hukkanen, Mika, Korhonen, Matti“…RESULTS: Three-dimensional culture, where human MSCs were grown on collagen sponges, markedly stimulated osteoblast differentiation; a fourfold increase in calcium deposition could be observed in both PLP and FCS groups. …”
Publicado 2015
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