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10861por Kołat, Damian, Kałuzińska-Kołat, Żaneta, Kośla, Katarzyna, Orzechowska, Magdalena, Płuciennik, Elżbieta, Bednarek, Andrzej K.“…Conclusion: WWOX is implicated in the positive feedback loop with LINC01137 that sponges WWOX-targeting miR-186-5p. This novel WWOX-containing lncRNA/miRNA/mRNA axis should be further investigated to depict its relationships in a broader context, which could contribute to BLCA research and treatment.…”
Publicado 2023
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10862por Buchmann, Kurt“…This ability is in multicellular animals associated with presence of phagocytes, bearing different names (amebocytes, hemocytes, coelomocytes) in various groups including animal sponges, worms, cnidarians, mollusks, crustaceans, chelicerates, insects, and echinoderms (sea stars and urchins). …”
Publicado 2014
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10863“…MEG3 was demonstrated to regulate the NF-κB signaling pathway by sponging miR-149-3p in CSE-treated HBE cells. In conclusion, these findings suggested that MEG3 promoted proliferation and inhibited apoptosis by regulating the NF-κB signal pathway via miR-149-3p in CSE-treated HBE cells. …”
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10864por Du, Xian-Fa, Cui, Hai-Tao, Pan, He-Hai, Long, Jun, Cui, Hao-Wen, Chen, Shun-Lun, Wang, Jian-Ru, Li, Ze-Min, Liu, Hui, Huang, Yong-Can, Wang, Hua, Zheng, Zhao-Min“…CONCLUSION: miR-133a-5p was upregulated by IL-1β to aggravate intervertebral disc degeneration via sponging FBXO6. Inhibiting miR-133a-5p expression or rescuing FBXO6 expression may be promising strategies for the treatment of IVDD. …”
Publicado 2021
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10865por Kubick, Norwin, Klimovich, Pavel, Bieńkowska, Irmina, Poznanski, Piotr, Łazarczyk, Marzena, Sacharczuk, Mariusz, Mickael, Michel-Edwar“…We found that opsin is the nearest receptor to have a common ancestor with the Tre1 family that has diverged in sponges. We investigated the positive selection of the Tre1 family using PAML. …”
Publicado 2021
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10866por Gu, Wenli, Jiang, Xiao, Wang, Wei, Mujagond, Prabhakar, Liu, Jingpeng, Mai, Zhaoyi, Tang, Hai, li, Simin, Xiao, Hui, Zhao, Jianjiang“…Rescue experiments illustrated that LINC01485 could promote osteogenesis by increasing RUNX2 expression by sponging miR-619-5p. CONCLUSION: LINC01485 could influence RUNX2 expression by acting as a ceRNA of miR-619-5p, thereby promoting osteogenic differentiation of hBMSCs. …”
Publicado 2022
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10867por Nelson, David B., Lafferty, Ashlyn, Venkatraman, Chinmayee, McDonald, Jeffrey G., Eckert, Kaitlyn M., McIntire, Donald D., Spong, Catherine Y.Enlace del recurso
Publicado 2022
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10868por Yu, Jianfeng, Luo, Jiawei, Li, Pengfei, Chen, Xiaojuan, Zhang, Guowei, Guan, Huaijin“…We found that hsa_circ_0002406 might upregulate FN1 and ADAM12 by sponging miR-26b-5p and miR-1-3p, respectively, thus promoting EMT in pterygium. …”
Publicado 2022
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10869por Lianou, Daphne T., Vasileiou, Natalia G. C., Michael, Charalambia K., Valasi, Irene, Mavrogianni, Vasia S., Caroprese, Mariangela, Fthenakis, George C.“…Control of reproduction was applied in 33.2% and 16.8% of sheep and goat farms, respectively, mostly by intravaginal progestagen sponges and less often by melatonin implants; multivariable analysis indicated five (availability of milking parlour, number of ewes in a farm, number of daily milkings, daily period spent by farmers at the farm, farming tradition in the family) and two (number of daily milkings, availability of milking parlour) predictors in sheep and goat farms, respectively. …”
Publicado 2022
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10870por Huang, Xianwei, Pan, Mandong, Du, Penghui, Chen, Yinrong, Zhang, Caixia, Lu, Wang, Lin, Jiyan“…In response to OGD treatment in vitro, MEG3 also activated the expression of sirtuin 1 (SIRT1) by Caco-2 cells via sponging miR-34a-3p. Furthermore, MEG3 relieved CA-induced intestinal barrier dysfunction through NF-κB signaling in vivo. …”
Publicado 2021
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10871“…Most clusters are regulated by several transcription factors, and miRNAs are also sponged by specific long non-coding RNAs. In some cases, co-expression of miRNA with other cluster members or host gene has been proven. miRNA expression patterns in cancer tissue, blood and faeces were compared. …”
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10872por Jing, Wang, Tuxiu, Xie, Xiaobing, Long, Guijun, Jiang, Lulu, Kang, Jie, Jiang, Lu, Ye, Liying, Zhan, Xiaoxing, Xiong, Jingjun, Lyu“…Bioinformatic analysis revealed that miR-137 was sponged by lncRNA GAS5, targeting INPP4B, and the result was confirmed by Luciferase activity assay. qRT-PCR and Western blotting showed that lncRNA GAS5 and INPP4B were over-expressed whereas miR-137 was downregulated in the blood of CA/CPR patients, OGD/R-stimulated astrocytes, and brain tissue of CA/CPR mice. …”
Publicado 2022
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10873por Xu, XiaoQiang, Sun, Rui, Li, YuanZhang, Wang, JiaXi, Zhang, Meng, Xiong, Xia, Xie, DanNi, Jin, Xin, Zhao, MingFeng“…Functional enrichment analysis indicated that TSC22D3 might promote AML progression. MIR143-3p sponging TSC22D3 might have anti-leukemia effect in adult AML. …”
Publicado 2023
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10874por Hsieh, Yu-Tung, Chen, Yi-Cheng, Chou, Yu-Chi, Kuo, Pin‑Yu, Yen, Yi-Ting, Tsai, Hung-Wen, Wang, Chrong-Reen“…SNHG16, a lncRNA, can enhance pulmonary inflammation by sponging microRNAs, and upregulate toll-like receptor 4 (TLR4) expression via stabilizing its mRNAs. …”
Publicado 2023
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10875“…CONCLUSIONS: In macrophages, lncGBP9 sponges miR-34a to rescue SOCS3 expression, therefore modulating macrophage polarization through STAT1/STAT6 signaling. …”
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10876por Zhang, Dong-Yan, Sun, Qing-Can, Zou, Xue-Jing, Song, Yang, Li, Wen-Wen, Guo, Ze-Qin, Liu, Shan-Shan, Liu, Li, Wu, De-Hua“…CONCLUSIONS: Our study revealed that UPK1A-AS1 promotes HCC development by accelerating cell cycle progression through interaction with EZH2 and sponging of miR-138-5p, suggesting that UPK1A-AS1 possesses substantial potential as a novel biomarker for HCC prognosis and therapy. …”
Publicado 2020
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10877“…MiR-365a-3p targeted signal transducer and activator of transcription 3 (STAT3) in breast cancer cells and circNOLC1 enhanced STAT3 expression by sponging miR-365a-3p. The overexpression of STAT3 could reverse miR-365a-3p or circNOLC1 depletion-inhibited proliferation and cancer stem cell properties of breast cancer. …”
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10878“…Competing endogenous RNAs (ceRNAs) play vital roles in oncogenesis and tumor progression by sponging microRNAs (miRNAs). Nevertheless, the regulatory mechanisms of survival-related ceRNA networks in CLL remain to be uncovered. …”
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10879por Yoshida, Sachiyo, Martines, José, Lawn, Joy E, Wall, Stephen, Souza, Joăo Paulo, Rudan, Igor, Cousens, Simon, Aaby, Peter, Adam, Ishag, Adhikari, Ramesh Kant, Ambalavanan, Namasivayam, Arifeen, Shams EI, Aryal, Dhana Raj, Asiruddin, Sk, Baqui, Abdullah, Barros, Aluisio JD, Benn, Christine S, Bhandari, Vineet, Bhatnagar, Shinjini, Bhattacharya, Sohinee, Bhutta, Zulfiqar A, Black, Robert E, Blencowe, Hannah, Bose, Carl, Brown, Justin, Bührer, Christoph, Carlo, Wally, Cecatti, Jose Guilherme, Cheung, Po–Yin, Clark, Robert, Colbourn, Tim, Conde–Agudelo, Agustin, Corbett, Erica, Czeizel, Andrew E, Das, Abhik, Day, Louise Tina, Deal, Carolyn, Deorari, Ashok, Dilmen, Uğur, English, Mike, Engmann, Cyril, Esamai, Fabian, Fall, Caroline, Ferriero, Donna M, Gisore, Peter, Hazir, Tabish, Higgins, Rosemary D, Homer, Caroline SE, Hoque, DE, Irgens, Lorentz, Islam, MT, de Graft–Johnson, Joseph, Joshua, Martias Alice, Keenan, William, Khatoon, Soofia, Kieler, Helle, Kramer, Michael S, Lackritz, Eve M, Lavender, Tina, Lawintono, Laurensia, Luhanga, Richard, Marsh, David, McMillan, Douglas, McNamara, Patrick J, Mol, Ben Willem J, Molyneux, Elizabeth, Mukasa, G. K, Mutabazi, Miriam, Nacul, Luis Carlos, Nakakeeto, Margaret, Narayanan, Indira, Olusanya, Bolajoko, Osrin, David, Paul, Vinod, Poets, Christian, Reddy, Uma M, Santosham, Mathuram, Sayed, Rubayet, Schlabritz–Loutsevitch, Natalia E, Singhal, Nalini, Smith, Mary Alice, Smith, Peter G, Soofi, Sajid, Spong, Catherine Y, Sultana, Shahin, Tshefu, Antoinette, van Bel, Frank, Gray, Lauren Vestewig, Waiswa, Peter, Wang, Wei, Williams, Sarah LA, Wright, Linda, Zaidi, Anita, Zhang, Yanfeng, Zhong, Nanbert, Zuniga, Isabel, Bahl, RajivEnlace del recurso
Publicado 2016
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10880por Zheng, Xiao, Chen, Lujun, Zhou, You, Wang, Qi, Zheng, Zhuojun, Xu, Bin, Wu, Chen, Zhou, Qi, Hu, Wenwei, Wu, Changping, Jiang, Jingting“…Recent studies have indicated that even though circRNAs generally regulate gene expression through miRNA sponges, they may encode small peptides in tumor pathogenesis. …”
Publicado 2019
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