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7581por Lengerke, Claudia, Fehm, Tanja, Kurth, Ralf, Neubauer, Hans, Scheble, Veit, Müller, Friederike, Schneider, Friederike, Petersen, Karen, Wallwiener, Diethelm, Kanz, Lothar, Fend, Falko, Perner, Sven, Bareiss, Petra M, Staebler, Annette“…BACKGROUND: The SRY-related HMG-box family of transcription factors member SOX2 has been mainly studied in embryonic stem cells as well as early foregut and neural development. …”
Publicado 2011
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7582por Ribas, Laia, Pardo, Belén G, Fernández, Carlos, Álvarez-Diós, José Antonio, Gómez-Tato, Antonio, Quiroga, María Isabel, Planas, Josep V, Sitjà-Bobadilla, Ariadna, Martínez, Paulino, Piferrer, Francesc“…A total of 1,410 sequences were confirmed to be related to reproduction and key genes involved in sex differentiation and maturation were identified for the first time in turbot (AR, AMH, SRY-related genes, CYP19A, ZPGs, STAR FSHR, etc.). …”
Publicado 2013
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7583por Ma, Kelong, Pan, Xiaorong, Fan, Pingsheng, He, Yinghua, Gu, Jun, Wang, Wei, Zhang, Tengyue, Li, Zonghai, Luo, Xiaoying“…The aberrant expression of several microRNAs is associated with CRC progression; however, the molecular mechanisms underlying this phenomenon are unclear. METHODS: miR-638 and SRY-box 2 (SOX2) expression levels were detected in 36 tumor samples and their adjacent, non-tumor tissues from patients with CRC, as well as in 4 CRC cell lines, using real-time quantitative RT-PCR (qRT-PCR). …”
Publicado 2014
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7584por van den Akker, Guus GH, Surtel, Don AM, Cremers, Andy, Rodrigues-Pinto, Ricardo, Richardson, Stephen M, Hoyland, Judith A, van Rhijn, Lodewijk W, Welting, Tim JM, Voncken, Jan Willem“…Immortalized cells were clonally expanded and characterized based on collagen type I, collagen type II, α1 (COL2A1), and SRY-box 9 (SOX9) protein expression profiles, as well as on expression of a subset of established in vivo NP cell lineage markers. …”
Publicado 2014
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7585por Pavlistova, Lenka, Izakova, Silvia, Zemanova, Zuzana, Bartuskova, Lucie, Langova, Martina, Malikova, Pavlina, Michalova, Kyra“…The cell line 45,X was confirmed with FISH in 35 % of interphase nuclei. The SRY locus was present on the dicentric chromosome. …”
Publicado 2016
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7586“…METHODS: We conducted immunohistochemical staining of C-MYC, Programmed cell death ligand 1 (PD-L1), CD8, Ki-67, p53 and SRY (sex determining region Y) -11 (SOX11) to investigate their expression in 64 patients with MCL. …”
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7587“…Moreover, the expression of SRY-related high-mobility group box 9 (SOX-9), aggrecan and col2α1 was suppressed. …”
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7588por Gao, Yang, Fang, Xin, Vincent, David F., Threadgill, David W., Bartholin, Laurent, Li, Qinglei“…Hematoxylin and eosin (H & E) staining, follicle counting, and immunohistochemistry and immunofluorescence analyses using antibodies directed to Ki67, forkhead box L2 (FOXL2), forkhead box O1 (FOXO1), inhibin alpha (INHA), and SRY (sex determining region Y)-box 9 were performed to determine the characteristics of the TGFBR1-CA(G9Cre) ovary. …”
Publicado 2017
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7589por Stadnicka, Katarzyna, Sławińska, Anna, Dunisławska, Aleksandra, Pain, Bertrand, Bednarczyk, Marek“…In quail, we found significant expression of four progenitor markers (LGR5 gene, SRY sex determining region Y-box 9, OCT4/cPOUV gene, and CD44 glycoprotein) that were largely present in the distal oviduct. …”
Publicado 2018
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7590por Tulake, Wuniqiemu, Yuemaier, Reziwanguli, Sheng, Lei, Ru, Mingfang, Lidifu, Dilare, Abudula, Abulizi“…The mRNA expression levels of aldehyde dehydrogenase 1 family member A1 (ALDH1A1), nanog homeobox (NANOG), POU class 5 homeobox 1 (OCT4), SRY-box 2 (SOX2) and twist family BHLH transcription factor 1 (Twist1) were determined using reverse transcription-quantitative PCR (RT-qPCR). …”
Publicado 2018
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7591por Bhat, Muzaffer A., Sharma, Jai B., Roy, Kallol K., Sengupta, Jayasree, Ghosh, Debabrata“…RESULTS: Six coding (AMELY, PCDH11, SRY, TGIF2LY, TSPY3, and USP9Y) and 10 non-coding (TTTY2, TTTY4C, TTTY5, TTTYY6, TTTY8, TTTY10, TTTY14, TTTY21, TTTY22, and TTTY23) genes exhibited a bimodal pattern of expression characterised by low expression in samples from fertile patients and high expression in samples from infertile patients. …”
Publicado 2019
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7592por Xu, Yang, Huang, Yan, Guo, Yibing, Xiong, Yicheng, Zhu, Shajun, Xu, Liancheng, Lu, Jingjing, Li, Xiaohong, Wan, Jian, Lu, Yuhua, Wang, Zhiwei“…Bioinformatic prediction and mechanistic analysis revealed that miR-690 plays a pivotal role during the differentiation of IPCs by directly targeting the transcription factor sex-determining region Y (SRY)-box9. Furthermore, downstream experiments indicated that miR-690 is likely to act as an inactivated regulator of the Wnt signaling pathway in this process. …”
Publicado 2019
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7593por Zhang, Hao, Zhang, Zhenya, Gao, Lili, Qiao, Zhengdong, Yu, Minghua, Yu, Bo, Yang, Tao“…TargetScan7.1 (http://www.targetscan.org/vert_71/) was used to predict the potential targets of miR-1-3p. SRY (sex determining region Y)-box 9 (SOX9), which has been previously shown to play an important role in HCC, was found to be a target of miR-1-3p. …”
Publicado 2019
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7594“…Bioinformatics analysis and luciferase reporter assay confirmed that miR-155-5p contributed to the progression of LSCC by directly binding to the 3′ untranslated region of SRY-related-HMG-box 10 (SOX10). In addition, MIR155HG and miR-155-5p were upregulated by the induction of transforming growth factor-β (TGF-β) and promoted the expression of mesenchymal markers synergistically. …”
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7595por Li, Ting, Hu, Pei-Shan, Zuo, Zhixiang, Lin, Jin-Fei, Li, Xingyang, Wu, Qi-Nian, Chen, Zhan-Hong, Zeng, Zhao-Lei, Wang, Feng, Zheng, Jian, Chen, Demeng, Li, Bo, Kang, Tie-Bang, Xie, Dan, Lin, Dongxin, Ju, Huai-Qiang, Xu, Rui-Hua“…MeRIP-seq revealed that SRY (sex determining region Y)-box 2 (SOX2) was the downstream gene of METTL3. …”
Publicado 2019
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7596por Nawas, Afshan F., Kanchwala, Mohammed, Thomas-Jardin, Shayna E., Dahl, Haley, Daescu, Kelly, Bautista, Monica, Anunobi, Vanessa, Wong, Ally, Meade, Rachel, Mistry, Ragini, Ghatwai, Nisha, Bayerl, Felix, Xing, Chao, Delk, Nikki A.“…Among these genes, we identified Sequestome-1 (SQSTM1/p62) and SRY (Sex-Determining Region Y)-Box 9 (SOX9) to be essential for survival of HR(−) BCa and PCa cell lines. …”
Publicado 2020
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7597por Chen, Xiaoxiang, Xu, Mu, Xu, Xueni, Zeng, Kaixuan, Liu, Xiangxiang, Pan, Bei, Li, Chenmeng, Sun, Li, Qin, Jian, Xu, Tao, He, Bangshun, Pan, Yuqin, Sun, Huilin, Wang, Shukui“…Furthermore, we identified SRY-related high-mobility-group box 4(SOX4) as a target of METTL14-mediated m6A modification. …”
Publicado 2020
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7598por Zhang, Jian, He, Haining, Wang, Kana, Xie, Yao, Yang, Zhongmei, Qie, Mingrong, Liao, Zhi, Zheng, Zhenrong“…Immunohistochemistry was employed to analyze the protein expression levels of Ki-67, proliferating cell nuclear antigen (PCNA), CD44, and SRY-box 4 (SOX4). RESULT: Downregulation of the mRNA expression levels of miR-326 was observed in cervical cancer cell lines and tumor tissue, while the levels of TCF4 were upregulated. …”
Publicado 2020
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7599por Kong, Desheng, Feng, Baofeng, Amponsah, Asiamah Ernest, He, Jingjing, Guo, Ruiyun, Liu, Boxin, Du, Xiaofeng, Liu, Xin, Zhang, Shuhan, Lv, Fei, Ma, Jun, Cui, Huixian“…At dpo 14, the immunostained hiPSC-NSCs were positive for SRY-related high-mobility-group (HMG)-box protein-2 (SOX2). …”
Publicado 2021
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7600por Huang, Jian-Lv, Wang, Xiang-Kun, Liao, Xi-Wen, Han, Chuang-Ye, Yu, Ting-Dong, Huang, Ke-Tuan, Yang, Cheng-Kun, Liu, Xiao-Guang, Yu, Long, Zhu, Guang-Zhi, Su, Hao, Qin, Wei, Han, Quan-Fa, Liu, Zheng-Qian, Zhou, Xin, Liu, Jun-Qi, Ye, Xin-Ping, Peng, Tao“…In this study, we assessed the power of sex-determining region Y (SRY)-related high-mobility group (HMG)-box 4(SOX4) gene to predict the clinical course of hepatocellular carcinoma (HCC). …”
Publicado 2021
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