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1981“…Early stages of encystation were marked by a striking decrease of endoplasmic reticulum-targeted variant-specific surface proteins and significant increases in cytoskeleton regulatory components, NEK protein kinases and proteins involved in protein folding and glycolysis. This was in stark contrast to cells in the later stages of encystation which presented a surprisingly similar proteome composition to non-encysting trophozoites. …”
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1982por Tsai, Pui-Jen“…The difference between males and females in the spatial distributions was stark. Furthermore, areas with a high morbidity of gastric cancer were clustered in aboriginal townships where the occurrence of Helicobacter pylori is frequent. …”
Publicado 2011
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1983“…A client library provides high-level distribution templates including MapReduce. This stark departure from the current reliance on expensive server hardware running “download and install” software has already gathered substantial community interest, as QM received more than 2.2 million API calls from 87 countries in 12 months. …”
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1984por O’Rourke, Brian P., Gomez-Ferreria, Maria Ana, Berk, Robin H., Hackl, Alexandra M. U., Nicholas, Matthew P., O’Rourke, Sean C., Pelletier, Laurence, Sharp, David J.“…The depletion of Cep192 results in a significant decrease in the level of centrosome-associated gamma-tubulin, likely explaining its impact on centrosome microtubule nucleation. However, in stark contrast to mitosis, Cep192 appears to maintain an antagonistic relationship with Pericentrin at interphase centrosomes. …”
Publicado 2014
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1985por Xiong, Hao, Morrison, Juliet, Ferris, Martin T., Gralinski, Lisa E., Whitmore, Alan C., Green, Richard, Thomas, Matthew J., Tisoncik-Go, Jennifer, Schroth, Gary P., Pardo-Manuel de Villena, Fernando, Baric, Ralph S., Heise, Mark T., Peng, Xinxia, Katze, Michael G.“…Host genetic variation drives the complexity and diversity of the host response by eliciting starkly different transcriptional profiles in response to a viral infection.…”
Publicado 2014
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1986por Johansson, Oskar N., Fahlberg, Per, Karimi, Elham, Nilsson, Anders K., Ellerström, Mats, Andersson, Mats X.“…Only knockout of PLDδ caused a loss of MTI-induced cell wall based defense against the non-host powdery mildew Erysiphe pisi. This is thus in stark contrast to the involvement of a multitude of PLD isoforms in the HR triggered by AvrRpm1 recognition.…”
Publicado 2014
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1987por Gardner, Andrew John“…The ground-breaking Leuven trials reported a mortality benefit of approximately 10% when using this technique, which led many to endorse its benefits. In stark contrast, the multi-center normoglycemia in intensive care evaluation–survival using glucose algorithm regulation (NICE-SUGAR) trial, not only failed to replicate this outcome, but showed TGC appeared to be harmful. …”
Publicado 2014
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1988por Parvani, Jenny G., Davuluri, Gangarao, Wendt, Michael K., Espinosa, Christine, Tian, Maozhen, Danielpour, David, Sossey-Alaoui, Khalid, Schiemann, William P.“…Functional disruption of Deptor expression in 4T07 cells significantly inhibited their proliferation and organoid growth in vitro, as well as prevented their colonization and tumor formation in the lungs of mice. In stark contrast, elevated Deptor expression was significantly associated with poorer overall survival of patients harboring estrogen receptor α–negative breast cancers. …”
Publicado 2015
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1989“…However, there was a remarkable decrease in photosynthetic capacity, and chlorosis and browning of leaves. In stark contrast, plantlets grown on Kyoto medium at 10 000 μmol mol(−1) CO(2) under high PPFD had a higher photosynthetic rate than plantlets grown on VW medium, and no chlorosis or browning was observed. …”
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1990por Antunes, Ana T., Goos, Yvonne J., Pereboom, Tamara C., Hermkens, Dorien, Wlodarski, Marcin W., Da Costa, Lydie, MacInnes, Alyson W.“…While the mechanisms underlying the cytopenia phenotype of patients with these mutations are not completely understood, it is believed that stabilization of the p53 tumor suppressor protein may induce apoptosis in the progenitor cells. In stark contrast, tumor cells from zebrafish with RP gene haploinsufficiency are unable to stabilize p53 even when exposed to acute DNA damage despite transcribing wild type p53 normally. …”
Publicado 2015
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1991“…Upon factoring out oligonucleotide composition and phylogenetic inertia, the residual AAC is poorly predictive of the microbes’ ecological preferences, in stark contrast with the original AAC. Moreover, highly expressed genes do not exhibit more prominent environment-related AAC signatures than lowly expressed genes, despite contributing more to the effective proteome. …”
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1992“…These observations are in stark contrast to the much faster expression divergence and acquisition of broad housekeeping roles we previously observed in Drosophila duplicate genes. …”
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1993“…BACKGROUND: Concerns have been raised about physician ownership of onsite advanced imaging equipment as allowed under Stark laws by the in-office ancillary service exception (IOASE). …”
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1994“…Both results stand in stark contrast to Cretaceous-Cenozoic bivalves, which showed significant levels of taxonomic clustering of extinctions in the Cretaceous, including strong clustering in the mass extinction, but taxonomically random extinctions in the Cenozoic. …”
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1995por Hoy, Marjorie A., Waterhouse, Robert M., Wu, Ke, Estep, Alden S., Ioannidis, Panagiotis, Palmer, William J., Pomerantz, Aaron F., Simão, Felipe A., Thomas, Jainy, Jiggins, Francis M., Murphy, Terence D., Pritham, Ellen J., Robertson, Hugh M., Zdobnov, Evgeny M., Gibbs, Richard A., Richards, Stephen“…Its genes exhibit elevated molecular evolution, with strikingly high numbers of intron gains and losses, in stark contrast to the deer tick Ixodes scapularis. …”
Publicado 2016
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1996por Sánchez-Garrido, Miguel Angel, Habegger, Kirk M., Clemmensen, Christoffer, Holleman, Cassie, Müller, Timo D., Perez-Tilve, Diego, Li, Pengyun, Agrawal, Archita S., Finan, Brian, Drucker, Daniel J., Tschöp, Matthias H., DiMarchi, Richard D., Kharitonenkov, Alexei“…Total and intact plasma FGF21 were observed to be elevated in TB-treated DIO mice but not lean animals where the metabolic impact of TB was significantly attenuated. Furthermore, and in stark contrast to naïve DIO mice, the administration of TB to obese FGF21 knockout animals demonstrated no appreciable effect on body weight or any other measures of metabolism. …”
Publicado 2016
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1997“…Illustrative energy transition case studies suggest the feasibility and benefit of empowering approaches, but also indicate there can be conflict between “green” and “just”, as evident though stark inequities in clean energy initiatives. To identify positive pathways forward, we compile priorities for an energy justice research agenda based on interactive and participatory practices aligning advocacy, activism, and academics.…”
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1998“…Their formation was found to be consistent with a ligand-exchange-induced comproportionation mechanism. In stark contrast to these phosphine-derived Ni complexes, the corresponding nitrogen-ligand-derived species were found to be likely competent catalysts in oxidation state I. …”
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1999por Antolík, Ján“…This specific configuration of lateral interactions is however in stark contrast with the known properties of the anatomical substrate, i.e., excitatory connections (mediating reinforcement) having longer reach than inhibitory ones (mediating competition). …”
Publicado 2017
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2000“…Photoluminescence (PL) peak shifts and Raman shifts can provide a relationship between quantum-confined Stark effect (QCSE) and IQE, as well as a comparison between strain and IQE. …”
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