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841por Navas-Moreno, Maria, Mehrpouyan, Majid, Chernenko, Tatyana, Candas, Demet, Fan, Ming, Li, Jian Jian, Yan, Ming, Chan, James W.“…However, when labeling live cells to monitor surface biomarker expression and dynamics, the nanoparticles are rapidly uptaken by the cells and become compartmentalized into different cellular regions. This behavior is in stark contrast to that of fluorescent antibody conjugates. …”
Publicado 2017
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842por Ball, Claudia R, Oppel, Felix, Ehrenberg, Karl Roland, Dubash, Taronish D, Dieter, Sebastian M, Hoffmann, Christopher M, Abel, Ulrich, Herbst, Friederike, Koch, Moritz, Werner, Jens, Bergmann, Frank, Ishaque, Naveed, Schmidt, Manfred, von Kalle, Christof, Scholl, Claudia, Fröhling, Stefan, Brors, Benedikt, Weichert, Wilko, Weitz, Jürgen, Glimm, Hanno“…The observed clonal succession of TIC activity in serial xenotransplantation is in stark contrast to the continuous activity of limited numbers of self‐renewing TICs within a fixed cellular hierarchy observed in other epithelial cancers and emphasizes the need to target TIC activation, rather than a fixed TIC population, in PDAC.…”
Publicado 2017
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843por Gao, Zhi, Vogels, Sjoerd N., Besemer, Matthieu, Karman, Tijs, Groenenboom, Gerrit C., van der Avoird, Ad, van de Meerakker, Sebastiaan Y. T.“…The angular scattering distributions for various final states of the NO radical are measured with high resolution using a crossed molecular beam apparatus that employs the combination of Stark deceleration and velocity map imaging. Rotational rainbows as well as diffraction oscillations are fully resolved in the scattering images. …”
Publicado 2017
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844por Sharp, Gemma C, Arathimos, Ryan, Reese, Sarah E, Page, Christian M, Felix, Janine, Küpers, Leanne K, Rifas-Shiman, Sheryl L, Liu, Chunyu, Burrows, Kimberley, Zhao, Shanshan, Magnus, Maria C, Duijts, Liesbeth, Corpeleijn, Eva, DeMeo, Dawn L, Litonjua, Augusto, Baccarelli, Andrea, Hivert, Marie-France, Oken, Emily, Snieder, Harold, Jaddoe, Vincent, Nystad, Wenche, London, Stephanie J, Relton, Caroline L, Zuccolo, Luisa“…CONCLUSION: Our findings suggest no association between maternal alcohol consumption and offspring cord blood DNA methylation. This is in stark contrast to the multiple strong associations previous studies have found for maternal smoking, which is similarly socially patterned. …”
Publicado 2018
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845por Steinchen, Wieland, Vogt, Marian S., Altegoer, Florian, Giammarinaro, Pietro I., Horvatek, Petra, Wolz, Christiane, Bange, Gert“…Here we present a structural and mechanistic characterization of RelP. In stark contrast to RelQ, RelP is not allosterically regulated by pppGpp and displays a different enzyme kinetic behavior. …”
Publicado 2018
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846por Diehl, Anne, Roske, Yvette, Ball, Linda, Chowdhury, Anup, Hiller, Matthias, Molière, Noel, Kramer, Regina, Stöppler, Daniel, Worth, Catherine L., Schlegel, Brigitte, Leidert, Martina, Cremer, Nils, Erdmann, Natalja, Lopez, Daniel, Stephanowitz, Heike, Krause, Eberhard, van Rossum, Barth-Jan, Schmieder, Peter, Heinemann, Udo, Turgay, Kürşad, Akbey, Ümit, Oschkinat, Hartmut“…Bacillus subtilis biofilms contain TasA as major proteinaceous component in addition to exopolysaccharides. In stark contrast to the initially unfolded biofilm proteins of other bacteria, TasA is a soluble, stably folded monomer, whose structure we have determined by X-ray crystallography. …”
Publicado 2018
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847“…We observe an APT-symmetric exceptional point (EP), inverse PT-symmetry breaking transition, and counterintuitive energy-difference conserving dynamics in stark contrast to the standard Hermitian dynamics keeping the system’s total energy constant. …”
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848por Flemer, Stevenson“…Greene's Protecting Groups in Organic Synthesis, the standard reference for the state of the art in this arena, offers no entries for selenium protective methodology, in stark comparison to its mention of the great variety of protecting groups germane to its chalcogen cousin sulfur. …”
Publicado 2011
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849“…We find that the IGHV and TRBV gene families exhibit starkly different patterns of variation. In addition to providing insight into the different evolutionary paths of the IGHV and TRBV loci, our results are also important to the adaptive immune repertoire sequencing community, where the lack of frequencies of common alleles and copy number variants is hampering existing analytical pipelines.…”
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850“…For a single ion we show that in this effective picture the quadrupole interaction is replaced by rescaled laser intensities and additional Stark shifts of the Rydberg levels. Hence this detrimental quadrupole coupling can be efficiently compensated by an appropriate increase of the Rabi frequencies. …”
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851por Cook, Timothy D., Tyler, Sarah F., McGuire, Caitlyn M., Zeller, Matthias, Fanwick, Phillip E., Evans, Dennis H., Peters, Dennis G., Ren, Tong“…The gaseous-product distribution for the active complexes was determined by means of controlled-potential electrolysis (CPE) and revealed that the phenyl derivative is the most active as well as the most selective for CO(2) reduction over proton reduction. Stark differences in the activity of the complexes studied are rationalized through comparison of their X-ray structures, absorption spectra, and CPE profiles. …”
Publicado 2017
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852“…Tree mortality during hot and dry conditions presents a stark reminder of the vulnerability of plant species to climatic extremes. …”
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853por Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Wang, Zheng, Dahlman, James E., Malagon-Lopez, Jose, Gujja, Sharvari, Cilfone, Nicholas A., Kauffman, Kevin J., Sun, Lele, Sun, Hongye, Zhang, Xinbo, Aryal, Binod, Canfran-Duque, Alberto, Liu, Rebecca, Kusters, Pascal, Sehgal, Alfica, Jiao, Yang, Anderson, Daniel G., Gulcher, Jeffrey, Fernandez-Hernando, Carlos, Lutgens, Esther, Schwartz, Martin A., Pober, Jordan S., Chittenden, Thomas W., Tellides, George, Simons, Michael“…These pro-inflammatory effects of endothelial TGFβ signaling are in stark contrast with its effects in other cell types and identify it as an important driver of atherosclerotic plaque growth and show the potential of cell-type specific therapeutic intervention aimed at control of this disease.…”
Publicado 2019
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854“…The surprisingly small band gap of Og moreover means that, in stark contrast to all other noble‐gas solids, the solid form of Og is a semiconductor.…”
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855por Zhan, Zhibing, ElKabbash, Mohamed, Cheng, JinLuo, Zhang, Jihua, Singh, Subhash, Guo, Chunlei“…More strikingly, the assembly maintains its floating ability even after severe damage and piercing in stark contrast to conventional watercrafts and aquatic devices. …”
Publicado 2019
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856por Li, Qiushi, Ramasamy, Sukanya, Singh, Pooja, Hagel, Jillian M., Dunemann, Sonja M., Chen, Xue, Chen, Rongji, Yu, Lisa, Tucker, Joseph E., Facchini, Peter J., Yeaman, Sam“…Copy number variation in critical BIA genes correlates with stark differences in alkaloid production, linking noscapine production with an 11-gene deletion, and increased thebaine/decreased morphine production with deletion of a T6ODM cluster. …”
Publicado 2020
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857“…The dramatic increase in survival rates is associated with enhancements in overall quality of life, which reflect a multidisciplinary, holistic approach to care. Current optimism starkly contrasts with the outlook and prognosis two decades ago, when failure to thrive and wasting syndrome from uncontrolled pediatric HIV infection resulted from poor oral intake, malabsorption, chronic diarrhea, and a persistently catabolic state. …”
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858“…An important improvement is the enhanced detection efficiency by resonant excitation to autoionizing [Formula: see text] electronic Rydberg states, resulting in narrow transitions due to reduced ac-Stark effects. Using known EF level energies, the level energies of X(v = 11, J = 1, 3–5) states are derived with accuracies of typically 0.002 cm(−1). …”
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859“…Vor allem in der Folge der verstärkten Globalisierung der Wertschöpfungsnetzwerke sowie die Verschlankung derartiger Netzwerke ist die Risikoexponierung vieler produzierender Unternehmen in den vergangenen Jahren stark angestiegen. Das Kapitel "Risiko-Management in der Produktion" bietet eine Einführung in Methoden zum Aufbau eines wirksamens Risiko-Managements im Bereich der Produktion. …”
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860por Kim, Ryung Il, Shin, Ju Ho, Lee, Jong Suk, Lee, Jung-Hyun, Lee, Albert S., Hwang, Seung Sang“…At a composite weight ratio of polyimide above 50 wt.%, a stark shift from amorphous to crystalline polyethylene glycol (PEG) phases were observed, accompanied by a drastic increase in both surface moduli and brittleness index. …”
Publicado 2020
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