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  1. 861
    “…We show that polyA runs do not elicit any response from No Go Decay (NGD) or result in the production of frameshifted proteins. This is in stark contrast to what we observe in human cells or T. thermophila, an organism with similar AT-content. …”
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    Plasmodium falciparum translational machinery condones polyadenosine repeats
  2. 862
    “…As the mechanisms responsible for such starkly different outcomes are not sufficiently explained, we aimed to explore what transcriptome rearrangements are used by glioblastoma cells in hypoxic areas. …”
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    Oxidative Stress—Part of the Solution or Part of the Problem in the Hypoxic Environment of a Brain Tumor
  3. 863
    “…The integration of experimental measurements and theoretical predictions reveals the starkly distinct underlying mechanism behind the relaxation dynamics of β-lactoglobulin amyloid fibrils, characterized by slow equilibration achieved through consecutive sigmoidal-like steps, and of cellulose nanocrystals, characterized by fast equilibration obtained through smooth relaxation dynamics. …”
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    Relaxation dynamics in bio-colloidal cholesteric liquid crystals confined to cylindrical geometry
  4. 864
    “…Using tracer particles, we show that the low-viscosity droplets are rapidly rotating internally, with flow velocities greatly exceeding the center-of-mass velocity. This is in stark contrast to the faster moving high-viscosity droplets with nearly vanishing internal flows. …”
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    Viscosity-enhanced droplet motion in sealed superhydrophobic capillaries
  5. 865
    “…By combining static and femtosecond infrared, Raman, and hyper-Raman spectroscopies for isotopically diluted water with ab initio molecular dynamics simulations, we find the vibrational coupling of the bending mode differs significantly from the stretch mode: the intramode intermolecular coupling of the bending mode is very weak, in stark contrast to the stretch mode. Our results elucidate the vibrational energy transfer pathways of water. …”
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    Vibrational couplings and energy transfer pathways of water’s bending mode
  6. 866
    “…Both our regression-based and deep-learning proxy measures provide highly accurate models of GO with training R(2) of 96% and 98%, respectively, along with other desirable qualities—stark improvements over the prevalent FS/S proxy (R(2) = 0.68). …”
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    From Regression Analysis to Deep Learning: Development of Improved Proxy Measures of State-Level Household Gun Ownership
  7. 867
    “…The ease with which normal hearing people perform this challenging task is in stark contrast to the difficulties that hearing-impaired subjects face in these situations. …”
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    Multichannel acoustic source and image dataset for the cocktail party effect in hearing aid and implant users
  8. 868
    “…Sulfonated cyclodextrins and nanoparticles that have recently shown broad-spectrum non-toxic virucidal activity against many heparan sulfates binding viruses showed inhibitory activity in the micromolar and nanomolar ranges, respectively. In stark contrast with the mechanisms that these compounds present for these other viruses, the inhibition against SARS-CoV-2 was found to be simply reversible.…”
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    SARS-CoV-2 Inhibition by Sulfonated Compounds
  9. 869
    “…We observe significant population decline in a majority of species examined, show decline was particularly severe, albeit size-dependent, among subalpine tree species, and provide evidence of widespread shifts in the size-structure of montane forests. Our findings offer a stark warning of changing forest composition and structure across the western US, and suggest that sustained anthropogenic and natural stress will likely result in broad-scale transformation of temperate forests globally.…”
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    Over half of western United States' most abundant tree species in decline
  10. 870
    “…Experimental validation via serial, high-content, and noninvasive assessments quantitatively confirmed that the MPS platform retained organoid viability and functionality for at least 10 days, in stark contrast to the acute decline observed overnight under static conditions. …”
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    Organoid microphysiological system preserves pancreatic islet function within 3D matrix
  11. 871
    “…[Image: see text] Mordenite (MOR)-type zeolites with a Si/Al molar ratio of up to 13 with crystallite sizes of ca. 60 nm were successfully synthesized from Al-rich aluminosilicates with a Si/Al ratio of 2 and additional SiO(2) under seed-assisted hydrothermal conditions for 6 h or longer without any organic structure-directing agents (OSDAs). In stark contrast, under the same hydrothermal conditions for 6 h, control experiments using starting reagent(s), such as Al-poor aluminosilicate, pure SiO(2), tetraethyl orthosilicate, and Al(NO(3))(3), all of which are typically employed for zeolite synthesis, failed to yield MOR-type zeolites. …”
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    Organic Structure-Directing Agent-Free Synthesis of Mordenite-Type Zeolites Driven by Al-Rich Amorphous Aluminosilicates
  12. 872
    “…In this review, we attempt to comprehensively outline the current advances revealing microglial sex differences in rodent and their potential implications for specific CNS diseases with a stark sex difference. A detailed understanding of molecular processes underlying microglial sex differences is of major importance in design of translational sex- and microglia-specific therapeutic approaches.…”
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    Uncovering sex differences of rodent microglia
  13. 873
    “…This problem is particularly intriguing as human behavior often proceeds on a time scale of seconds, which is in stark contrast to the much faster millisecond time-scale of neuronal processing in our brains. …”
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    Synaptic learning rules for sequence learning
  14. 874
    “…Interestingly, most muscularis macrophages span multiple gut layers in stark contrast to their mammalian counterparts typically restricted to a single layer. …”
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    Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes
  15. 875
    “…As largely documented in the literature, the stark restrictions enforced worldwide in 2020 to curb the COVID-19 pandemic also curtailed the production of air pollutants to some extent. …”
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    Air pollution perception in ten countries during the COVID-19 pandemic
  16. 876
    “…While several platforms exist to facilitate the development of virtual lab experiments, they typically present researchers with a stark trade-off between usability and functionality. …”
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    Empirica: a virtual lab for high-throughput macro-level experiments
  17. 877
    “…Utilizing a detailed kinetic analysis and the vibrational Stark effect, we quantify the changes in rates and electric fields in the Michaelis and acyl-enzyme complexes for penicillin G and cefotaxime to ascertain the evolutionary role of electric fields to modulate function. …”
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    The Interplay of Electrostatics and Chemical Positioning in the Evolution of Antibiotic Resistance in TEM β-Lactamases
  18. 878
    “…The small microbial community subsisted with high potential cell-specific rates of energy metabolism, which approach the rates of active surface sediments and laboratory cultures. Our discovery is in stark contrast to the extremely low metabolic rates otherwise observed in the deep subseafloor. …”
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    Rapid metabolism fosters microbial survival in the deep, hot subseafloor biosphere
  19. 879
    “…Surprisingly, cone opsin–deficient cones survive for at least 12 mo, which is in stark contrast to the rapid rod degeneration observed in rhodopsin-deficient mice, suggesting that cone opsins are dispensable for cone viability. …”
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    Visual pigment–deficient cones survive and mediate visual signaling despite the lack of outer segments
  20. 880
    “…Here, we will first review the initial discovery of artemisinin, an extraordinary journey that was in stark contrast with many drugs in western medicine. …”
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    Discovery and repurposing of artemisinin
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