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  1. 1301
  2. 1302
    por Matoba, Kazuma
    Publicado 2022
    “…In the twenty-first century the world faces the stark reality that’s far from any visions of an ideal world, accompanied by an epidemic of social inequality and global injustice. …”
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  3. 1303
    “…This NK-mediated cytotoxicity is often restricted by cellular defects caused by disease-associated mechanisms, which can lead to disease progression. A stark feature of AML is the low/no expression of the cognate HLA ligands for the activating KIR receptors, due to which these tumor cells evade NK-mediated lysis. …”
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  4. 1304
    por Patwardhan, Avinash
    Publicado 2023
    “…There seems to be a great diversity in viewpoints and visions regarding how AI would affect human destiny—right from confident optimism to stark doomsaying and all in between. However, not much attention is being paid to the insidious long-term effects on human societies, many of them being unintended consequences, that AI has the potential to create over a short period of time. …”
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  5. 1305
    “…Exposure risk decreased as household income and neighborhood collective efficacy increased, though stark racial/ethnic inequities remained. Across racial/ethnic groups, adolescents in poor households in moderate or high collective efficacy neighborhoods had a similar risk of past-year firearm homicide exposure as middle-to-high income adolescents in low collective efficacy neighborhoods. …”
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  6. 1306
    “…Mortality due to complications from so-called ‘long COVID’ is a stark illustration of this potential, but the impacts of such post-infection mortality (PIM) on epidemic dynamics are not known. …”
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  7. 1307
    “…In this commentary, we aim to shed light on these racial disparities, focusing specifically on the stark inequities related to the timely diagnosis and subsequent dermatological care of HS in the United States. …”
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  8. 1308
    “…Large delays are typically destabilizing but, surprisingly, short delays can substantially increase community stability. Moreover, in stark contrast to delay-free systems, delays dictate that communities with more abundant species can be less stable than ones with less abundant species. …”
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  9. 1309
    “…In this paper, a MEMS north-finding system (NFS) based on virtual maytagging (VM) is presented for the first time. In stark contrast to previous schemes of MEMS-based NFSs (e.g., carouseling, maytagging) and the abandoning rate table, we developed a honeycomb disk resonator gyroscope (HDRG) and two commercial accelerometers for azimuth detection. …”
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  10. 1310
    “…Besides structurally supporting the PH domain, the BAR domain also contributes to Rab binding through a small surface region in the vicinity of the PH domain. In stark contrast to the helix-dominated, Rab-binding domains previously reported, APPL1 PH domain employs β-strands to interact with Rab5. …”
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  11. 1311
    por Holt, James B
    Publicado 2007
    “…The analysis revealed significant and stark patterns of poverty. A distinctive north–south demarcation of low versus high poverty concentrations was found, along with isolated pockets of high and low poverty within areas in which the predominant poverty rates were opposite. …”
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  12. 1312
    “…Furthermore, there were dramatic alterations in striatal plasticity during the acquisition of a motor skill, with most neurons in mutants showing negative modulation of firing rate, starkly contrasting with the predominantly positive modulation seen in control animals. …”
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  13. 1313
    por Malizia, Nicholas
    Publicado 2013
    “…Additionally, they show that weaker signals of space-time interaction are those most affected by the introduced deficiencies. However, in stark contrast to previous investigations into the impact of these input data problems on global tests of space-time interaction, this local metric is revealed to be only minimally affected by the degree of inaccuracy and incompleteness introduced in these experiments.…”
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  14. 1314
    “…The use of medical marijuana has continued to gain support among states, and is currently legal in 16 states and the District of Columbia. This is in stark contrast to the federal government’s stance of zero-tolerance, which has led to a heated legal debate in the United States. …”
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  15. 1315
  16. 1316
    “…Analyses of these isolated catalytic fragments have revealed stark contrasts in their amenability to recombinant expression and their physical properties: e.g., a >16°C variance in thermal stability, a 3-fold difference in catalytic activity and disparities in their inhibitor binding profiles. …”
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  17. 1317
    “…In addition, the rate of PHA-DCOI weight loss, post-onset, reduced by about 150%; in contrast a recorded weight loss of only 0.05% per day for P(HB-co-HV) with a 10% DCOI loading was observed. This is in stark contrast to the unmodified PHB film, where a recorded weight loss of only 0.75% per day was made. …”
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  18. 1318
    “…Protein expression levels of Kirrel B are inverse to the occurrence of cell fusion events during in vitro myogenesis which is in stark contrast to the expression profile of Rst and Kirre during myogenesis in Drosophila. …”
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  19. 1319
    “…Simulation of mechanical trauma of a wound by scratching a monolayer of fibroblasts from CERK(+/+) mice demonstrated steadily increasing levels of arachidonic acid in a time-dependent manner in stark contrast to CERK(−/−) fibroblasts. This observed difference was reflected in scratch-induced eicosanoid levels. …”
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  20. 1320
    “…In the history of vaccine development, the synthetic vaccine is a milestone that is in stark contrast with traditional vaccines based on live-attenuated or inactivated microorganisms. …”
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