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141“…Drawing from an ever-expanding compendium of experimental and clinical studies, this review details the current state-of-play and provides a perspective of chromatin-dependent mechanisms implicated in diabetic complications, with a special focus on diabetic nephropathy. …”
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142“…In order to both understand the ongoing disagreement about avian origins and generate a prediction about the future of the debate, here we use a revised model of scientific practice to assess the current and historical state of play surrounding the topic of bird evolutionary origins. …”
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143“…The analysis of the current state of play of the sector suggests that a large potential can be foreseen for near future; the expected increase in biomethane production is based also on the possibility to convert residual feedstocks, such as Municipal Solid Wastes. …”
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144por Khalili, Khadijeh, Inhester, Ludger, Arnold, Caroline, Gertsen, Anders S., Andreasen, Jens Wenzel, Santra, Robin“…To date, alternating co-polymers based on electron-rich and electron-poor units are the most attractive materials to control functionality of organic semiconductor layers in which ultrafast excited-state processes play a key role. We present a computational study of the photoinduced excited-state dynamics of the 4-(2-thienyl)-2,1,3-benzothiadiazole (BT-1T) molecule, which is a common building block in the backbone of π-conjugated polymers used for organic electronics. …”
Publicado 2020
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145“…In this review we give a snapshot of the current state of play in this field of research and the available information about the clinical trials. …”
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146por D'Angelo, Carla S., Hermes, Azure, McMaster, Christopher R., Prichep, Elissa, Richer, Étienne, van der Westhuizen, Francois H., Repetto, Gabriela M., Mengchun, Gong, Malherbe, Helen, Reichardt, Juergen K. V., Arbour, Laura, Hudson, Maui, du Plessis, Kelly, Haendel, Melissa, Wilcox, Phillip, Lynch, Sally Ann, Rind, Shamir, Easteal, Simon, Estivill, Xavier, Thomas, Yarlalu, Baynam, Gareth“…Herein, we provide an overview of the state of play of current barriers and considerations identified by the taskforce, to further stimulate awareness of these issues and the passage toward solutions. …”
Publicado 2020
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147“…Saudi Arabia’s Vision 2030 encourages the state to play a renewed role in development in light of the UN’s declaration of the “right to development.” …”
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148“…Avoidance of increasing anti-microbial resistance with astute anti-microbial stewardship is paramount if we are to successfully manage M. genitalium infection. We examine the state of play regarding anti-microbial resistance and how to combat this, including currently available anti-microbials, resistance-guided therapy and novel therapeutic approaches. …”
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149por Nielsen, Søren Saxmose, Bicout, Dominique Joseph, Calistri, Paolo, Canali, Elisabetta, Drewe, Julian Ashley, Garin‐Bastuji, Bruno, Gonzales Rojas, Jose Luis, Gortazar Schmidt, Christian, Herskin, Mette, Michel, Virginie, Miranda Chueca, Miguel Angel, Padalino, Barbara, Pasquali, Paolo, Roberts, Helen Clare, Sihvonen, Liisa Helena, Spoolder, Hans, Stahl, Karl, Velarde, Antonio, Viltrop, Arvo, Winckler, Christoph, Guardabassi, Luca, Hilbert, Friederike, Mader, Rodolphe, Aznar, Inma, Baldinelli, Francesca, Alvarez, Julio“…Details of the methodology used for this assessment are explained in a separate opinion. A global state of play of antimicrobial resistant Staphylococcus pseudintermedius, Staphylococcus aureus, Staphylococcus schleiferi, Escherichia coli, Proteus mirabilis, Klebsiella spp., Enterobacter spp., Pseudomonas aeruginosa, Clostridium perfringens, Clostridioides difficile, Enterococcus faecalis and Enterococcus faecium has been provided. …”
Publicado 2021
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150“…We reviewed over 300 biomarkers with the aim to provide an in-depth summary of the current state-of-play regarding diagnostic biomarkers in PC (serum, urinary, salivary, faecal, pancreatic juice and biliary fluid).…”
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151por Nielsen, Søren Saxmose, Bicout, Dominique Joseph, Calistri, Paolo, Canali, Elisabetta, Drewe, Julian Ashley, Garin‐Bastuji, Bruno, Gonzales Rojas, Jose Luis, Gortazar Schmidt, Christian, Herskin, Mette, Michel, Virginie, Miranda Chueca, Miguel Angel, Padalino, Barbara, Pasquali, Paolo, Roberts, Helen Clare, Spoolder, Hans, Stahl, Karl, Velarde, Antonio, Viltrop, Arvo, Winckler, Christoph, Dewulf, Jeroen, Guardabassi, Luca, Hilbert, Friederike, Mader, Rodolphe, Baldinelli, Francesca, Alvarez, Julio“…Details of the methodology used for this assessment are explained in a separate opinion. A global state of play on antimicrobial resistance in clinical isolates of Staphylococcus aureus, Escherichia coli (non‐VTEC), Pseudomonas aeruginosa, Dichelobacter nodosus, Moraxella ovis, Mannheimia haemolytica, Pasteurella multocida, Mycoplasma ovipneumoniae, Mycoplasma agalactiae, Trueperella pyogenes, Streptococcus uberis, Bibersteinia trehalosi, Campylobacter fetus, Mycoplasma mycoides subsp. capri, Mycoplasma capricolum subsp. capricolum, Fusobacterium necrophorum is provided. …”
Publicado 2021
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152por Nielsen, Søren Saxmose, Bicout, Dominique Joseph, Calistri, Paolo, Canali, Elisabetta, Drewe, Julian Ashley, Garin‐Bastuji, Bruno, Gonzales Rojas, Jose Luis, Gortazar Schmidt, Christian, Herskin, Mette, Michel, Virginie, Miranda Chueca, Miguel Angel, Padalino, Barbara, Pasquali, Paolo, Roberts, Helen Clare, Sihvonen, Liisa Helena, Spoolder, Hans, Stahl, Karl, Velarde, Antonio, Viltrop, Arvo, Winckler, Christoph, Dewulf, Jeroen, Guardabassi, Luca, Hilbert, Friederike, Mader, Rodolphe, Baldinelli, Francesca, Alvarez, Julio“…Details of the methodology used for this assessment are explained in a separate opinion. A global state of play of antimicrobial resistant Escherichia coli, Streptococcus suis, Actinobacillus pleuropneumoniae, Pasteurella multocida, Glaeserella parasuis, Bordetella bronchiseptica, Staphylococcus aureus, Staphylococcus hyicus, Brachyspira hyodysenteriae, Trueperella pyogenes, Erysipelothrix rhusiopathiae, Streptococcus dysgalactiae, Mycoplasma hyosynoviae, Mycoplasma hyorhinis, Mycoplasma hyopneumoniae and Brachyspira pilosicoli has been provided. …”
Publicado 2021
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153por Nielsen, Søren Saxmose, Bicout, Dominique Joseph, Calistri, Paolo, Canali, Elisabetta, Drewe, Julian Ashley, Garin‐Bastuji, Bruno, Gonzales Rojas, Jose Luis, Gortazar Schmidt, Christian, Herskin, Mette, Michel, Virginie, Miranda Chueca, Miguel Angel, Padalino, Barbara, Pasquali, Paolo, Roberts, Helen Clare, Sihvonen, Liisa Helena, Spoolder, Hans, Stahl, Karl, Velarde, Antonio, Viltrop, Arvo, Winckler, Christoph, Dewulf, Jeroen, Guardabassi, Luca, Hilbert, Friederike, Mader, Rodolphe, Baldinelli, Francesca, Alvarez, Julio“…Details on the methodology used for this assessment are explained in a separate opinion. A global state of play of antimicrobial‐resistant Actinobacillus equuli, Dermatophilus congolensis, Enterococcus spp., Escherichia coli, Klebsiella pneumoniae, Pasteurella spp., Pseudomonas aeruginosa, Rhodococcus equi, Staphylococcus aureus and Streptococcus dysgalactiae subsp. dysgalactiae/equisimilis and Streptococcus equi subsp. equi and subsp. zooepidemicus has been provided. …”
Publicado 2021
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154“…While the reasons for this are many, a significant factor contributing to the current state of play is the pressing need for methodological innovation and relevant scientific approaches that have the capacity to support the translation of novel solutions into ‘real world’ rural contexts. …”
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155por Drogba, Landry, Diaby, Raïssa, Djondé, Grace, Konan, Landry, Okamon, Jean-Marcel, Meuga, Wilfried, N'Dri, Dominique“…This study should continue with the inclusion of a larger number of patients in order to review the state of play of the management of high-grade gliomas in Côte d'Ivoire.…”
Publicado 2023
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156por Bagnato, Gianluca, Bitto, Alessandra, Irrera, Natasha, Pizzino, Gabriele, Sangari, Donatella, Cinquegrani, Maurizio, Roberts, William Neal, Atteritano, Marco, Altavilla, Domenica, Squadrito, Francesco, Bagnato, Gianfilippo, Saitta, Antonino“…INTRODUCTION: Recent advances suggest that the cellular redox state may play a significant role in the progression of fibrosis in systemic sclerosis (SSc). …”
Publicado 2013
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157por An, Soo Jeong, Lee, Seung-Hwan, Lee, Seo-Young, Kwon, Jae-Woo, Lee, Seung-Joon, Kim, Young-Ju“…It is necessary to consider how factors associated with the amount of ambulatory activity–even in an early diagnosed state–can play an important role in femur fracture in subjects with parkinsonism.…”
Publicado 2017
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158por Kumar, Shaji, Larson, Dirk R., Dispenzieri, Angela, Therneau, Terry M., Murray, David L., Leif Bergsagel, P., Kyle, Robert A., Vincent Rajkumar, S.“…We demonstrate for the first time, the increased risk of developing MG in patients with elevated serum FLC, suggesting that an underlying inflammatory state may play an etiologic role.…”
Publicado 2019
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159por Ferguson, Caleb, Inglis, Sally C, Breen, Paul P, Gargiulo, Gaetano D, Byiers, Victoria, Macdonald, Peter S, Hickman, Louise D“…The focus groups generated the following 3 overarching, interrelated themes: (1) the current state of play, understanding the perceived challenges of patient cardiac monitoring in hospitals, (2) priorities in cardiac monitoring, what parameters new technologies should measure, and (3) cardiac monitoring of the future, “the ideal device.” …”
Publicado 2020
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160por Osaka, Natsuki, Hirota, Yoshihisa, Ito, Doshun, Ikeda, Yoshiki, Kamata, Ryo, Fujii, Yuki, Chirasani, Venkat R., Campbell, Sharon L., Takeuchi, Koh, Senda, Toshiya, Sasaki, Atsuo T.“…The Switch regions lie within or proximal to the G2 and G3 motifs, and undergo dynamic conformational changes between the GDP-bound “OFF” state and GTP-bound “ON” state. They play an important role in the recognition of regulatory factors (GEFs and GAPs) and effectors. …”
Publicado 2021
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